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Published in: Insights into Imaging 1/2019

Open Access 01-12-2019 | Computed Tomography | Original Article

CT density of cervical thymus, in comparison with mediastinal thymus

Authors: Anitha Sen, Jiji Valsalamony, Jubie Raj

Published in: Insights into Imaging | Issue 1/2019

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Abstract

Objectives

Cervical component of thymus is noted more in children and young adults than in older age group. CT texture (lobules of soft tissue interspersed with fat), similarity with CT density of mediastinal thymus and continuity with mediastinal thymus on sagittal/coronal images, are given as the criteria for diagnosis of the cervical thymus. But CT densities of cervical and mediastinal components of the thymus may vary. The purpose of our study was to compare CT densities of cervical and mediastinal parts of the thymus, in cases where ultrasonography correlation was available.

Methods

We retrospectively identified 22 patients who had undergone CT between May 2015 and May 2017 and in whom ultrasonography (USG) correlation was available. CT densities of cervical and mediastinal components of thymus were measured.

Results

1.
CT density of cervical thymus is lower than the CT density of mediastinal thymus by ~ 25 HU.
 
2.
There is a moderate positive correlation between CT densities of cervical and mediastinal parts of the thymus.
 
3.
CT densities of both cervical and mediastinal thymus were found to reduce with age, but the reduction was statistically significant only in the cervical thymus in this study.
 

Conclusions

  • CT densities of cervical and mediastinal components of the thymus may vary, with CT density of cervical thymus being lower. There is a positive correlation between CT densities of cervical and mediastinal parts of the thymus.
  • CT density of cervical thymus reduces with age.
Understanding these may help avoid confusion on CT and avoid the need for correlative USG, saving time and effort.
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Literature
1.
go back to reference Prabhu AV, Kale HA, Branstetter BF 4th (2015) Residual cervical thymus: a normal CT finding that may be present throughout patients’ lives. AJNR Am J Neuroradiol 36(8):1525–1528CrossRef Prabhu AV, Kale HA, Branstetter BF 4th (2015) Residual cervical thymus: a normal CT finding that may be present throughout patients’ lives. AJNR Am J Neuroradiol 36(8):1525–1528CrossRef
2.
go back to reference Costa NS, Laor T, Donnelly LF (2010) Superior cervical extension of the thymus: a normal finding that should not be mistaken for a mass. Radiology 256:238–242CrossRef Costa NS, Laor T, Donnelly LF (2010) Superior cervical extension of the thymus: a normal finding that should not be mistaken for a mass. Radiology 256:238–242CrossRef
3.
go back to reference Liu ME, Branstetter BF 4th, Whetstone J, Escott EJ (2006) Normal CT appearance of the distal thoracic duct. AJR Am J Roentgenol 187(6):1615–1620CrossRef Liu ME, Branstetter BF 4th, Whetstone J, Escott EJ (2006) Normal CT appearance of the distal thoracic duct. AJR Am J Roentgenol 187(6):1615–1620CrossRef
4.
go back to reference Bansal AG, Oudsema R, Masseaux JA, Rosenberg HK (2018) US of pediatric superficial masses of the head and neck. Radiographics. 38(4):1239–1263CrossRef Bansal AG, Oudsema R, Masseaux JA, Rosenberg HK (2018) US of pediatric superficial masses of the head and neck. Radiographics. 38(4):1239–1263CrossRef
5.
go back to reference Dua SG, Purandare NC, Shah S, Maitra R, Rangarajan V (2010) Cervical extension of the thymus mimicking metastatic recurrence of Ewing sarcoma on PET/CT. Indian J Nucl Med 25(4):176PubMedPubMedCentral Dua SG, Purandare NC, Shah S, Maitra R, Rangarajan V (2010) Cervical extension of the thymus mimicking metastatic recurrence of Ewing sarcoma on PET/CT. Indian J Nucl Med 25(4):176PubMedPubMedCentral
6.
go back to reference Han BK, Babcock DS, Oestreich AE (1989) Normal thymus in infancy: sonographic characteristics. Radiology. 170(2):471–474CrossRef Han BK, Babcock DS, Oestreich AE (1989) Normal thymus in infancy: sonographic characteristics. Radiology. 170(2):471–474CrossRef
7.
go back to reference Han BK, Yoon HK, Suh YL (2001) Thymic ultrasound. II. Diagnosis of aberrant cervical thymus. Pediatr Radiol 31(7):480–487CrossRef Han BK, Yoon HK, Suh YL (2001) Thymic ultrasound. II. Diagnosis of aberrant cervical thymus. Pediatr Radiol 31(7):480–487CrossRef
8.
go back to reference Nasseri F, Eftekhari F (2010) Clinical and radiologic review of the normal and abnormal thymus: pearls and pitfalls. Radiographics. 30(2):413–428CrossRef Nasseri F, Eftekhari F (2010) Clinical and radiologic review of the normal and abnormal thymus: pearls and pitfalls. Radiographics. 30(2):413–428CrossRef
9.
go back to reference Zielke AM, Swischuk LE, Hernandez JA (2007) Ectopic cervical thymic tissue: can imaging obviate biopsy and surgical removal? Pediatr Radiol 37(11):1174–1177CrossRef Zielke AM, Swischuk LE, Hernandez JA (2007) Ectopic cervical thymic tissue: can imaging obviate biopsy and surgical removal? Pediatr Radiol 37(11):1174–1177CrossRef
10.
go back to reference Kissin CM, Husband JE, Nicholas D, Eversman W (1987) Benign thymic enlargement in adults after chemotherapy: CT demonstration. Radiology 163:67–70CrossRef Kissin CM, Husband JE, Nicholas D, Eversman W (1987) Benign thymic enlargement in adults after chemotherapy: CT demonstration. Radiology 163:67–70CrossRef
11.
go back to reference Araki T, Nishino M, Gao W et al (2016) Normal thymus in adults: appearance on CT and associations with age, sex, BMI and smoking. Eur Radiol 26(1):15–24CrossRef Araki T, Nishino M, Gao W et al (2016) Normal thymus in adults: appearance on CT and associations with age, sex, BMI and smoking. Eur Radiol 26(1):15–24CrossRef
12.
go back to reference Araki T, Sholl LM, Gerbaudo VH, Hatabu H, Nishino M (2014) Imaging characteristics of pathologically proven thymic hyperplasia: identifying features that can differentiate true from lymphoid hyperplasia. AJR Am J Roentgenol 202(3):471–478CrossRef Araki T, Sholl LM, Gerbaudo VH, Hatabu H, Nishino M (2014) Imaging characteristics of pathologically proven thymic hyperplasia: identifying features that can differentiate true from lymphoid hyperplasia. AJR Am J Roentgenol 202(3):471–478CrossRef
13.
go back to reference Ackman JB, Kovacina B, Carter BW et al (2013) Sex difference in normal thymic appearance in adults 20-30 years of age. Radiology. 268(1):245–253CrossRef Ackman JB, Kovacina B, Carter BW et al (2013) Sex difference in normal thymic appearance in adults 20-30 years of age. Radiology. 268(1):245–253CrossRef
14.
go back to reference Araki T, Sholl LM, Gerbaudo VH, Hatabu H, Nishino M (2014) Thymic measurements in pathologically proven normal thymus and thymic hyperplasia: intraobserver and interobserver variabilities. Acad Radiol 21(6):733–742CrossRef Araki T, Sholl LM, Gerbaudo VH, Hatabu H, Nishino M (2014) Thymic measurements in pathologically proven normal thymus and thymic hyperplasia: intraobserver and interobserver variabilities. Acad Radiol 21(6):733–742CrossRef
Metadata
Title
CT density of cervical thymus, in comparison with mediastinal thymus
Authors
Anitha Sen
Jiji Valsalamony
Jubie Raj
Publication date
01-12-2019
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 1/2019
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1186/s13244-019-0781-z

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