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Published in: Archives of Virology 10/2008

01-10-2008 | Brief Report

Complete nucleotide sequence analysis of a Dengue-1 virus isolated on Easter Island, Chile

Authors: C. Cáceres, V. Yung, P. Araya, J. Tognarelli, E. Villagra, L. Vera, J. Fernández

Published in: Archives of Virology | Issue 10/2008

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Abstract

Dengue-1 viruses responsible for the dengue fever outbreak in Easter Island in 2002 were isolated from acute-phase sera of dengue fever patients. In order to analyze the complete genome sequence, we designed primers to amplify contiguous segments across the entire sequence of the viral genome. RT-PCR products obtained were cloned, and complete nucleotide and deduced amino acid sequences were determined. This report constitutes the first complete genetic characterization of a DENV-1 isolate from Chile. Phylogenetic analysis shows that an Easter Island isolate is most closely related to Pacific DENV-1 genotype IV viruses.
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Metadata
Title
Complete nucleotide sequence analysis of a Dengue-1 virus isolated on Easter Island, Chile
Authors
C. Cáceres
V. Yung
P. Araya
J. Tognarelli
E. Villagra
L. Vera
J. Fernández
Publication date
01-10-2008
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 10/2008
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-008-0200-0

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