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World Journal of Surgical Oncology

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Open Access 01-12-2015 | Research

Comparative study of self-expanding metal stent and intraluminal radioactive stent for inoperable esophageal squamous cell carcinoma

Authors: Dong Tian, Hongying Wen, Maoyong Fu

Published in: World Journal of Surgical Oncology | Issue 1/2016

Abstract

Background

We compared the effectiveness of self-expanding metal stent alone vs. radioactive stent embedded with ¹²⁵I seeds implantation insertion in patients of inoperable esophageal squamous cell cancer combined with malignant esophageal stenosis.

Methods

We studied two groups of patients with stenosis attribute to inoperable esophageal squamous cell carcinoma. Group A had placed self-expanding metal stent alone insertion; group B encountered radioactive stent embedded with ¹²⁵I seeds. Patients were followed up by monthly home visits or telephone interview. Survival time was analyzed with Kaplan-Meier analysis. Log rank test was used to analyze factors of survival time for all significant differences.

Results

There was no significant difference between the two groups of all baseline characteristics. There was no statistical difference in complications including massive hematemesis, pain more than 1 month, stent migration, and restenosis. Survival time and causes of death such as tumor metastasis, massive hemorrhage, non-tumor-related factors, and restenosis were comparable between the two groups (P > 0.05). The medical costs were significantly less in group A than those in group B (P < 0.01).

Conclusions

Radioactive stent embedded with ¹²⁵I seeds was not significant in improving survival rate, but showed to increase hospitalization costs compared to self-expandable metal stent alone in treating inoperable esophageal squamous cell carcinoma stricture.

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Title: Comparative study of self-expanding metal stent and intraluminal radioactive stent for inoperable esophageal squamous cell carcinoma
Authors: Dong Tian
Hongying Wen
Maoyong Fu
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2016
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/s12957-016-0768-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Comparative study of self-expanding metal stent and intraluminal radioactive stent for inoperable esophageal squamous cell carcinoma

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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