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Diabetologia
Published in: Diabetologia 7/2007

01-07-2007 | Letter

Comment on: Tchoukalova Y, Koutsari C, Jensen M (2007) Committed subcutaneous preadipocytes are reduced in human obesity. Diabetologia 50:151–157

Authors: R. Monteiro, C. Calhau, I. Azevedo

Published in: Diabetologia | Issue 7/2007

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Excerpt

To the Editor: In their recent paper [1], Tchoukalova et al. provide very interesting data on preadipocyte availability according to the body fat distribution phenotype: preadipocytes of upper-body-obese women exhibited reduced differentiation and were more prone to apoptosis than preadipocytes isolated from adipose tissue of lower-body-obese or lean women. Moreover, in obese women preadipocytes constituted a much lower percentage of adipose tissue stromovascular cells, fat cell size was higher and fat cell number per gram of tissue was lower than in lean women. …
Literature
1.
Tchoukalova Y, Koutsari C, Jensen M (2007) Committed subcutaneous preadipocytes are reduced in human obesity. Diabetologia 50:151–157CrossRefPubMed
2.
Monteiro R, Calhau C, Azevedo I (2006) Adipocyte size and liability to cell death. Obes Surg 16:804–806CrossRefPubMed
3.
Calhau C, Azevedo I, Monteiro R (2007) Obstructive sleep apnoea and adipocyte death. Eur J Heart Fail 9:103–104CrossRefPubMed
4.
Cinti S, Mitchell G, Barbatelli G et al (2005) Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 46:2347–2355CrossRefPubMed
5.
Tanabe Y, Koga M, Saito M et al (2004) Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPARγ2. J Cell Sci 117:3605–3614CrossRefPubMed
Metadata
Title
Comment on: Tchoukalova Y, Koutsari C, Jensen M (2007) Committed subcutaneous preadipocytes are reduced in human obesity. Diabetologia 50:151–157
Authors
R. Monteiro
C. Calhau
I. Azevedo
Publication date
01-07-2007
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 7/2007
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-007-0636-x

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