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Open Access 01-12-2010 | Review

Colorectal carcinoma associated with schistosomiasis: a possible causal relationship

Authors: Omer E H Salim, Hytham K S Hamid, Salwa O Mekki, Suleiman H Suleiman, Shakir Z Ibrahim

Published in: World Journal of Surgical Oncology | Issue 1/2010

Abstract

The association between schistosomiasis and colorectal malignancy has long been suggested in the literature, but it is not uniformly accepted. In the Far East, considerable evidence supports an etiological link between Schistosoma japonicum and colorectal cancer. However, the available data regarding the role of Schistosoma mansoni in colorectal carcinogenesis are conflicting and most often do not show causality. We report on a patient with sigmoid colonic cancer coexisting with schistosomiasis, and we provide a comprehensive review of the literature regarding the epidemiology and pathobiology of this association.

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Gryseels B, Polman K, Clerinx J, Kestens L: Human schistosomiasis. Lancet. 2006, 368 (9541): 1106-1118. 10.1016/S0140-6736(06)69440-3.CrossRefPubMed

Yosry A: Schistosomiasis and neoplasia. Contrib Microbiol. 2006, 13: 81-100. full_text.CrossRefPubMed

International Agency for Research on Cancer: Infection with Schistosomes, Liver Flukes and Helicobacter Pylori. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 1994, Lyon, France: IARC Press, 61:

Ross AG, Bartley PB, Sleigh AC, Olds GR, Li Y, Williams GM, McManus DP: Schistosomiasis. N Engl J Med. 2002, 346 (16): 1212-1220. 10.1056/NEJMra012396.CrossRefPubMed

Zhao ES: Cancer of the colon and schistosomiasis. J R Soc Med. 1981, 74 (9): 645-PubMedCentralPubMed

Xu Z, Su D: Schistosoma japonicum and colorectal cancer: an epidemiological study in the People's Republic of China. Int J Cancer. 1984, 34 (3): 315-318. 10.1002/ijc.2910340305.CrossRefPubMed

Chen J, Campbell TC, Li J, Peto R: Diet, Life-style, and Mortality in China. A Study of the Characteristics of 65 Chinese Counties. 1990, Oxford: Oxford University Press

Guo W, Zheng W, Li JY, Chen JS, Blot WJ: Correlations of colon cancer mortality with dietary factors, serum markers, and schistosomiasis in China. Nutr Cancer. 1993, 20 (1): 13-20. 10.1080/01635589309514266.CrossRefPubMed

Inaba Y: A cohort study on the causes of death in an endemic area of schistosomiasis japonica in Japan. Ann Acad Med Singapore. 1984, 13 (2): 142-148.PubMed

10.

Mayer DA, Fried B: The Role of Helminth Infections in Carcinogenesis. Advances in Parasitology. Edited by: Muller R, Rollinson D, Hay SI. 2007, London: Academic Press, 65: 239-296. full_text.

11.

Qiu DC, Hubbard AE, Zhong B, Zhang Y, Spear RC: A matched, case-control study of the association between Schistosoma japonicum and liver and colon cancers, in rural China. Ann Trop Med Parasitol. 2005, 99 (1): 47-52. 10.1179/136485905X19883.CrossRefPubMed

12.

Parkin DM, Arslan A, Bieber A, Bouvy O, Muir CS, Owor R, Whelan S: Cancer Occurrence in Developing Countries. International Agency for Research on Cancer (IARC) Scientific Publication No. 75. 1986, Lyon, France: IARC Press

13.

Waku M, Napolitano L, Clementini E, Staniscia T, Spagnolli C, Andama A, Kasiriye P, Innocenti P: Risk of cancer onset in sub-Saharan Africans affected with chronic gastrointestinal parasitic diseases. Int J Immunopathol Pharmacol. 2005, 18 (3): 503-511.PubMed

14.

Shindo K: Significance of schistosomiasis japonica in the development of cancer of the large intestine: Report of a case and review of the literature. Dis Colon Rectum. 1976, 19 (5): 460-469. 10.1007/BF02590835.CrossRefPubMed

15.

Chen MC, Hu JC, Chang PY, Chuang CY, Tsao PF, Chang SH, Wang FP, Ch'en TL, Chou SC: Pathogenesis of carcinoma of the colon and rectum in schistosomiasis japonica: a study on 90 cases. Chin Med J. 1965, 84 (8): 513-525.

16.

Ming-Chai C, Chi-Yuan C, Pei-Yu C, Jen-Chun H: Evolution of colorectal cancer in schistosomiasis: transitional mucosal changes adjacent to large intestinal carcinoma in colectomy specimens. Cancer. 1980, 46 (7): 1661-1675. 10.1002/1097-0142(19801001)46:7<1661::AID-CNCR2820460728>3.0.CO;2-O.CrossRefPubMed

17.

Matsuda K, Masaki T, Ishii S, Yamashita H, Watanabe T, Nagawa H, Muto T, Hirata Y, Kimura K, Kojima S: Possible associations of rectal carcinoma with schistosoma japonicum infection and membranous nephropathy: a case report with a review. Jpn J Clin Oncol. 1999, 29 (11): 576-578. 10.1093/jjco/29.11.576.CrossRefPubMed

18.

Chen MC, Chang PY, Chuang CY, Chen YJ, Wang FP, Tang YC, Chou SC: Colorectal cancer and schistomiasis. Lancet. 1981, 1 (8227): 971-973.PubMed

19.

Yu XR, Chen PH, Xu JY, Xiao S, Shan ZJ, Zhu SJ: Histological classification of schistosomal egg induced polyps of colon and their clinical significance. An analysis of 272 cases. Chin Med J(Engl). 1991, 104 (1): 64-70.

20.

Uthman S, Farhat B, Farah S, Uwayda M: Association of Schistosoma mansoni with colonic carcinoma. Am J Gastroenterol. 1991, 86 (9): 1283-1284.PubMed

21.

Al-Mashat F, Sibiany A, Radwi A, Bahadur Y, Al-Radi A, Ahmed GE: Rectal cancer associated with schistosomiasis: report of two cases and review of the literature. Ann Saudi Med. 2001, 21 (1-2): 65-67.PubMed

22.

Ameh EA, Nmadu PT: Colorectal Adenocarcinoma in children and adolescents: a report of 8 patients from Zaria, Nigeria. West Afr J Med. 2000, 19 (4): 273-276.PubMed

23.

Ojo OS, Odesanmi WO, Akinola OO: The surgical pathology of colorectal carcinoma in Nigerians. Trop Gastroenterol. 1991, 13 (2): 180-184.

24.

Dimmette RM, Elwi AM, Sproate HF: Relationship of schistosomiasis to polyposis and adenocareinoma of large intestine. Am J Clin Patho. 1956, 26 (3): 266-276.

25.

Madbouly KM, Senagore AJ, Mukerjee A, Hussien AM, Shehata MA, Navine P, Delaney CP, Fazio VW: Colorectal cancer in a population with endemic Schistosoma mansoni: is this an at-risk population?. Int J Colorectal Dis. 2007, 22 (2): 175-181. 10.1007/s00384-006-0144-3.CrossRefPubMed

26.

Mohamed AR, Al Karawi MA, Yasawy MI: Schistosomal colonic disease. Gut. 1990, 31 (4): 439-442. 10.1136/gut.31.4.439.PubMedCentralCrossRefPubMed

27.

Cheever AW, Kamel IA, Elwi AM, Mosimann JE, Danner R, Sippel JE: Schistosoma mansoni and S. haematobium infections in Egypt. III. Extrahepatic pathology. Am J Trop Med Hyg. 1987, 27 (1): 55-75.

28.

Ishii A, Matsuoka H, Aji T, Ohta N, Arimoto S, Wataya Y, Hayatsu H: Parasite infection and cancer: with special emphasis on Schistosoma japonicum infections (Trematoda). A review. Mutat Res. 1994, 305 (2): 273-281.CrossRefPubMed

29.

Lin M, Hanai J, Gui L: Peanut lectin-binding sites and mucins in benign and malignant colorectal tissues associated with schistomatosis. Histol Histopathol. 1998, 13 (4): 961-966.PubMed

30.

Soliman AS, Bondy ML, El-Badawy SA, N Mokhtar, Eissa S, Bayoumy S, Seifeldin IA, Houlihan PS, Lukish JR, Watanabe T, Chan AOO, Zhu D, Amos CI, Levin B, Hamilton SR: Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients. Br J Cancer. 2001, 85 (7): 1037-1046. 10.1054/bjoc.2001.1838.PubMedCentralCrossRefPubMed

31.

Rosin MP, Anwar WA, Ward AJ: Inflammation, chromosomal instability, and cancer: the schistosomiasis model. Cancer Res. 1994, 54 (Suppl 7): 1929-1933.

32.

Van Riet E, Hartgers FC, Yazdanbakhsh M: Chronic helminth infections induce immunomodulation: consequences and mechanisms. Immunobiology. 2007, 212 (6): 475-490. 10.1016/j.imbio.2007.03.009.CrossRefPubMed

33.

Long XC, Bahgat M, Chlichlia K, Ruppel A, Li YL: Detection of inducible nitric oxide synthase in Schistosoma japonicum and S. mansoni. J Helminthol. 2004, 78 (1): 47-50. 10.1079/JOH2003202.CrossRefPubMed

34.

Herrera LA, Benitez-Bribiesca L, Mohar A, Ostrosky-Wegman P: Role of infectious diseases in human carcinogenesis. Environ Mol Mutagen. 2005, 45 (2-3): 284-303. 10.1002/em.20122.CrossRefPubMed

35.

Trakatelli C, Frydas S, Hatzistilianou M, Papadopoulos E, Simeonidou I, Founta A, Paludi D, Petrarca C, Castellani ML, Papaioannou N, Salini V, Conti P, Kempuraj D, Vecchiet J: Chemokines as markers for parasite-induced inflammation and tumors. Int J Biol Markers. 2005, 20 (4): 197-203.PubMed

36.

Chieffi PP: Interrelationship between schistosomiasis and concomitant diseases. Mem Inst Oswaldo Cruz. 1992, 87 (Suppl 4): 291-296.CrossRefPubMed

37.

Tuazon CU, Nash T, Cheever A, Neva F: Interaction of Schistosoma japonicum with Salmonellae and other gram-negative bacteria. J Infect Dis. 1985, 152 (4): 722-726.CrossRefPubMed

38.

Hope ME, Hold GL, Kain R, El-Omar EM: Sporadic colorectal cancer--role of the commensal microbiota. FEMS Microbiol Lett. 2005, 244 (1): 1-7. 10.1016/j.femsle.2005.01.029.CrossRefPubMed

39.

Ishii A, Matsuoka H, Aji T, Hayatsu H, Wataya Y, Arimoto S, Tokuda H: Evaluation of the mutagenicity and the tumor-promoting activity of parasite extracts: Schistosoma japonicum and Clonorchis sinensis. Mutat Res. 1989, 224 (2): 229-233. 10.1016/0165-1218(89)90160-2.CrossRefPubMed

40.

Osada Y, Kumagai T, Masuda K, Suzuki T, Kanazawa T: Mutagenicity evaluation of Schistosoma spp. extracts by the umu-test and V79/HGPRT gene mutation assay. Parasitol Int. 2005, 54 (1): 29-34. 10.1016/j.parint.2004.08.004.CrossRefPubMed

41.

Zhang R, Takahashi S, Orita S, Yoshida A, Maruyama H, Shirai T, Ohta N: p53 gene mutations in rectal cancer associated with schistosomiasis japonica in Chinese patients. Cancer Lett. 1998, 131 (2): 215-221. 10.1016/S0304-3835(98)00154-2.CrossRefPubMed

42.

Goodman JE, Hofseth LJ, Hussain SP, Harris CC: Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease. Environ Mol Mutagen. 2004, 44 (1): 3-9. 10.1002/em.20024.CrossRefPubMed

43.

Itzkowitz SH, Yio X: Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol. 2004, 287 (1): G7-17. 10.1152/ajpgi.00079.2004.CrossRefPubMed

44.

Zalata KR, Nasif WA, Ming SC, Lotfy M, Nada NA, El-Hak NG, Leech SH: p53, Bcl-2 and C-Myc expressions in colorectal carcinoma associated with schistosomiasis in Egypt. Cell Oncol. 2005, 27 (4): 245-253.PubMed

Title: Colorectal carcinoma associated with schistosomiasis: a possible causal relationship
Authors: Omer E H Salim
Hytham K S Hamid
Salwa O Mekki
Suleiman H Suleiman
Shakir Z Ibrahim
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2010
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-8-68

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Colorectal carcinoma associated with schistosomiasis: a possible causal relationship

Abstract

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Abstract

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