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Allergy, Asthma & Clinical Immunology
Published in: Allergy, Asthma & Clinical Immunology 2/2014

Open Access 01-12-2014 | Meeting abstract

Co-exposure to allergen and diesel exhaust enhance inflammatory responses in human airway submucosa

Authors: Ali Hosseini, Tillie L Hackett, Jeremy Hirota, Kelly McNagny, Chris Carlsten

Published in: Allergy, Asthma & Clinical Immunology | Special Issue 2/2014

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Excerpt

Asthma is a chronic condition described by inflammation of the airways and lungs. Diesel exhaust (DE) is a major contributor to ambient particulate matter (PM) air pollution. There is rising evidence that PM acts as adjuvant on the immune responses and may lead to augmentation of allergic inflammation [1, 2]. We aim to elucidate if DE increases allergen-induced inflammation and cellular immune response in the airways of atopic human subjects. …
Literature
1.
Riedl M, Diaz-Sanchez D: Biology of diesel exhaust effects on respiratory function. Journal of Allergy and Clinical Immunology. 2005, 115 (2): 221-228. 10.1016/j.jaci.2004.11.047.CrossRefPubMed
2.
Nel AE, Diaz-Sanchez D, Ng D, Hiura T, Saxon A: Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. Journal of Allergy and Clinical Immunology. 1998, 102 (4): 539-554. 10.1016/S0091-6749(98)70269-6.CrossRefPubMed
Metadata
Title
Co-exposure to allergen and diesel exhaust enhance inflammatory responses in human airway submucosa
Authors
Ali Hosseini
Tillie L Hackett
Jeremy Hirota
Kelly McNagny
Chris Carlsten
Publication date
01-12-2014
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1710-1492-10-S2-A57

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