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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2015

Open Access 01-12-2015 | Endocrine Tumors

Clinicopathological Significance of Minimal Extrathyroid Extension in Solitary Papillary Thyroid Carcinomas

Authors: Chang Gok Woo, MD, Chang Ohk Sung, MD, Yun Mi Choi, MD, Won Gu Kim, MD, Tae Yong Kim, MD, Young Kee Shong, MD, Won Bae Kim, MD, Suck Joon Hong, MD, Dong Eun Song, MD

Published in: Annals of Surgical Oncology | Special Issue 3/2015

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Abstract

Background

The definitive diagnosis of minimal extrathyroid extension (ETE) is subjective because a well-defined true capsule is absent in the thyroid gland. We subclassified the extent of minimal ETE and investigated the clinicopathological significance of the presence of minimal ETE in patients with solitary papillary thyroid carcinomas (PTCs) and solitary papillary thyroid microcarcinomas (PTMCs).

Methods

A series of 546 patients with solitary PTCs, including 144 patients with solitary PTMCs, were retrospectively analyzed. Whether the presence of minimal ETE had an effect on recurrence-free survival (RFS) along with other clinicopathological parameters was investigated.

Results

The only independent prognostic factor found to be associated with recurrence was the presence of LN metastasis in solitary PTC (p = 0.002) but not in solitary PTMC groups (p = 0.073). The presence of minimal ETE had no effect on RFS in both solitary PTC (p = 0.053) and solitary PTMC (p = 0.816).

Conclusions

The presence of minimal ETE has no significant influence on RFS in solitary PTC and PTMC. There is a risk of overrepresenting the T3 category in solitary PTC and PTMC patients with minimal ETE.
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Metadata
Title
Clinicopathological Significance of Minimal Extrathyroid Extension in Solitary Papillary Thyroid Carcinomas
Authors
Chang Gok Woo, MD
Chang Ohk Sung, MD
Yun Mi Choi, MD
Won Gu Kim, MD
Tae Yong Kim, MD
Young Kee Shong, MD
Won Bae Kim, MD
Suck Joon Hong, MD
Dong Eun Song, MD
Publication date
01-12-2015
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2015
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-015-4659-0

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