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Open Access 01-12-2012 | Methodology

Clinical target volume delineation including elective nodal irradiation in preoperative and definitive radiotherapy of pancreatic cancer

Authors: Luciana Caravatta, Giuseppina Sallustio, Fabio Pacelli, Gilbert DA Padula, Francesco Deodato, Gabriella Macchia, Mariangela Massaccesi, Vincenzo Picardi, Savino Cilla, Alfonso Marinelli, Numa Cellini, Vincenzo Valentini, Alessio G Morganti

Published in: Radiation Oncology | Issue 1/2012

Abstract

Background

Radiotherapy (RT) is widely used in the treatment of pancreatic cancer. Currently, recommendation has been given for the delineation of the clinical target volume (CTV) in adjuvant RT. Based on recently reviewed pathologic data, the aim of this study is to propose criteria for the CTV definition and delineation including elective nodal irradiation (ENI) in the preoperative and definitive treatment of pancreatic cancer.

Methods

The anatomical structures of interest, as well as the abdominal vasculature were identified on intravenous contrast-enhanced CT scans of two different patients with pancreatic cancer of the head and the body. To delineate the lymph node area, a margin of 10 mm was added to the arteries.

Results

We proposed a set of guidelines for elective treatment of high-risk nodal areas and CTV delineation. Reference CT images were provided.

Conclusions

The proposed guidelines could be used for preoperative or definitive RT for carcinoma of the head and body of the pancreas. Further clinical investigations are needed to validate the defined CTVs.

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Title: Clinical target volume delineation including elective nodal irradiation in preoperative and definitive radiotherapy of pancreatic cancer
Authors: Luciana Caravatta
Giuseppina Sallustio
Fabio Pacelli
Gilbert DA Padula
Francesco Deodato
Gabriella Macchia
Mariangela Massaccesi
Vincenzo Picardi
Savino Cilla
Alfonso Marinelli
Numa Cellini
Vincenzo Valentini
Alessio G Morganti
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2012
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-7-86

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical target volume delineation including elective nodal irradiation in preoperative and definitive radiotherapy of pancreatic cancer

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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