Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Radiation Oncology
Published in: Radiation Oncology 1/2012

Open Access 01-12-2012 | Review

Iodine-125 brachytherapy for brain tumours - a review

Authors: Silke B Schwarz, Niklas Thon, Katharina Nikolajek, Maximilian Niyazi, Joerg-Christian Tonn, Claus Belka, Friedrich-Wilhelm Kreth

Published in: Radiation Oncology | Issue 1/2012

Login to get access

Abstract

Iodine-125 brachytherapy has been applied to brain tumours since 1979. Even though the physical and biological characteristics make these implants particularly attractive for minimal invasive treatment, the place for stereotactic brachytherapy is still poorly defined.
An extensive review of the literature has been performed, especially concerning indications, results and complications. Iodine-125 seeds have been implanted in astrocytomas I-III, glioblastomas, metastases and several other tumour entities. Outcome data given in the literature are summarized. Complications are rare in carefully selected patients.
All in all, for highly selected patients with newly diagnosed or recurrent primary or metastatic tumours, this method provides encouraging survival rates with relatively low complication rates and a good quality of life.
Appendix
Available only for authorised users
Literature
1.
Holm HH, Stroyer I, Hansen H, Stadil F: ULTRASONICALLY GUIDED PERCUTANEOUS INTERSTITIAL IMPLANTATION OF I125 SEEDS IN CANCER-THERAPY. British Journal of Radiology 1981,54(644):665-670. 10.1259/0007-1285-54-644-665PubMed
2.
Matthews CME: HALF-LIFE OF IODINE-125. Physics in Medicine and Biology 1960,5(1):45-47. 10.1088/0031-9155/5/1/305PubMed
3.
Kim JH, Hilaris B: IODINE 125 SOURCE IN INTERSTITIAL TUMOR THERAPY - CLINICAL AND BIOLOGIC CONSIDERATIONS. American Journal of Roentgenology 1975,123(1):163-169.
4.
Mundinger F, Ostertag CB, Birg W, Weigel K: STEREOTACTIC TREATMENT OF BRAIN-LESIONS - BIOPSY, INTERSTITIAL RADIOTHERAPY (IR-192 AND I125) AND DRAINAGE PROCEDURES. Applied Neurophysiology 1980,43(3-5):198-204.PubMed
5.
Bernstein M, Gutin PH: Interstitial irradiation of brain tumors: a review. Neurosurgery 1981,9(6):741-750. 10.1227/00006123-198112000-00022PubMed
6.
Jani SK, Hitchon PW, Vangilder JC, Wen BC: NORMAL BRAIN IRRADIATION DURING STEREOTACTIC BRAIN IMPLANTS USING RADIOACTIVE I-125. Applied Neurophysiology 1987,50(1-6):310-313.PubMed
7.
Viola A, Major T, Julow J: Comparison of I-125 stereotactic brachytherapy and LINAC radiosurgery modalities based on physical dose distribution and radiobiological efficacy. Radiation Research 2006,165(6):695-702. 10.1667/RR3529.1PubMed
8.
Luxton G, Petrovich Z, Jozsef G, Nedzi LA, Apuzzo ML: Stereotactic radiosurgery: principles and comparison of treatment methods. Neurosurgery 1993,32(2):241-259. discussion 259 10.1227/00006123-199302000-00014PubMed
9.
Larson DA, Flickinger JC, Loeffler JS: The radiobiology of radiosurgery. Int J Radiat Oncol Biol Phys 1993,25(3):557-561. 10.1016/0360-3016(93)90080-FPubMed
10.
Larsson B: Radiobiological Fundamentals in Radiosurgery. Radiosurgery 1992, 3-14.
11.
Krishnaswamy V: DOSE DISTRIBUTION AROUND AN I125 SEED SOURCE IN TISSUE. Radiology 1978,126(2):489-491.PubMed
12.
Sneed PK, McDermott MW, Gutin PH: Interstitial brachytherapy procedures for brain tumors. Seminars in Surgical Oncology 1997,13(3):157-166. 10.1002/(SICI)1098-2388(199705/06)13:3<157::AID-SSU2>3.0.CO;2-6PubMed
13.
McDermott MW, Sneed PK, Gutin PH: Interstitial brachytherapy for malignant brain tumors. Seminars in Surgical Oncology 1998,14(1):79-87. 10.1002/(SICI)1098-2388(199801/02)14:1<79::AID-SSU10>3.0.CO;2-4PubMed
14.
Nath R, Anderson LL, Luxton G, Weaver KA, Williamson JF, Meigooni AS: DOSIMETRY OF INTERSTITIAL BRACHYTHERAPY SOURCES - RECOMMENDATIONS OF THE AAPM RADIATION-THERAPY COMMITTEE TASK GROUP NO 43. Medical Physics 1995,22(2):209-234. 10.1118/1.597458PubMed
15.
Sewchand W, Drzymala RE, Amin PP, Salcman M, Salazar OM: RADIATION CONTROL IN THE INTENSIVE-CARE UNIT FOR HIGH-INTENSITY IR-192 BRAIN IMPLANTS. Neurosurgery 1987,20(4):584-588. 10.1227/00006123-198704000-00013PubMed
16.
Kreth FW, Thon N, Siefert A, Tonn JC: The place of interstitial brachytherapy and radiosurgery for low-grade gliomas. Adv Tech Stand Neurosurg 2010, 35: 183-212. 10.1007/978-3-211-99481-8_7PubMed
17.
Mundinger F: [Stereotaxic interstitial therapy of non-resectable intracranial tumors with iridium-192 and iodine-125]. Strahlentherapie [Sonderb] 1981, 76: 90-112.
18.
Fike JR, Cann CE, Phillips TL, Bernstein M, Gutin PH, Turowski K, Weaver KA, Davis RL, Higgins RJ, Dasilva V: Radiation Brain-Damage Induced by Interstitial I125 Sources - a Canine Model Evaluated by Quantitative Computed-Tomography. Neurosurgery 1985,16(4):530-537. 10.1227/00006123-198504000-00015PubMed
19.
Groothuis DR, Wright DC, Ostertag CB: The Effect of I-125 Interstitial Radiotherapy on Blood-Brain-Barrier Function in Normal Canine Brain. J Neurosurg 1987,67(6):895-902. 10.3171/jns.1987.67.6.0895PubMed
20.
Ostertag CB: Brachytherapy - Interstitial Implant Radiosurgery. Acta Neurochir 1993, 79-84.
21.
Meli JA, Dicker CS, Schulz RJ: COMPUTER-APPLICATIONS TO RADIOACTIVE-SEED - BRAIN-TUMOR IMPLANTS. Computerized Medical Imaging and Graphics 1989,13(3):269-274. 10.1016/0895-6111(89)90133-XPubMed
22.
Hosobuchi Y, Phillips TL, Stupar TA, Gutin PH: INTERSTITIAL BRACHYTHERAPY OF PRIMARY BRAIN-TUMORS - PRELIMINARY-REPORT. J Neurosurg 1980,53(5):613-617. 10.3171/jns.1980.53.5.0613PubMed
23.
Gutin PH, Prados MD, Phillips TL, Wara WM, Larson DA, Leibel SA, Sneed PK, Levin VA, Weaver KA, Silver P, et al.: EXTERNAL IRRADIATION FOLLOWED BY AN INTERSTITIAL HIGH-ACTIVITY I-125 IMPLANT BOOST IN THE INITIAL TREATMENT OF MALIGNANT GLIOMAS - NCOG STUDY 6G-82-2. International Journal of Radiation Oncology Biology Physics 1991,21(3):601-606. 10.1016/0360-3016(91)90676-U
24.
Laperriere NJ, Leung PMK, McKenzie S, Milosevic M, Wong S, Glen J, Pintilie M, Bernstein M: Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma. International Journal of Radiation Oncology Biology Physics 1998,41(5):1005-1011. 10.1016/S0360-3016(98)00159-X
25.
Scharfen CO, Sneed PK, Wara WM, Larson DA, Phillips TL, Prados MD, Weaver KA, Malec M, Acord P, Lamborn KR, et al.: HIGH-ACTIVITY I-125 INTERSTITIAL IMPLANT FOR GLIOMAS. International Journal of Radiation Oncology Biology Physics 1992,24(4):583-591. 10.1016/0360-3016(92)90702-J
26.
Kumar PP, Good RR, Patil AA, Leibrock LG: PERMANENT HIGH-ACTIVITY I-125 IN THE MANAGEMENT OF PETROCLIVAL MENINGIOMAS - CASE-REPORTS. Neurosurgery 1989,25(3):436-442. 10.1227/00006123-198909000-00019PubMed
27.
Ling CC: GOLD-198 PALLADIUM-103 AND IODINE-125 PERMANENT IMPLANTS RADIOBIOPHYSICAL CONSIDERATIONS. Medical Physics (Woodbury) 1991,18(3):637.
28.
Bauerkirpes B, Sturm V, Schlegel W, Lorenz WJ: COMPUTERIZED OPTIMIZATION OF I125 IMPLANTS IN BRAIN-TUMORS. International Journal of Radiation Oncology Biology Physics 1988,14(5):1013-1023. 10.1016/0360-3016(88)90027-2
29.
Meningher H, Benary V, Chaitchick S, Akselrod S: A PLANNING METHOD FOR I-125 IMPLANTS IN CANCER-THERAPY. Physics in Medicine and Biology 1990,35(12):1633-1640. 10.1088/0031-9155/35/12/004PubMed
30.
Rosenow UF, Findlay PA, Wright DC: THE NCI-ATLAS OF DOSE DISTRIBUTIONS FOR REGULAR I-125 BRAIN IMPLANTS. Radiotherapy and Oncology 1987,10(2):127-139. 10.1016/S0167-8140(87)80055-5PubMed
31.
Saw CB, Suntharalingam N, Ayyangar KM, Tupchong L: DOSIMETRIC CONSIDERATIONS OF STEREOTACTIC BRAIN IMPLANTS. International Journal of Radiation Oncology Biology Physics 1989,17(4):887-891. 10.1016/0360-3016(89)90083-7
32.
Weaver K, Smith V, Lewis JD, Lulu B, Barnett CM, Leibel SA, Gutin P, Larson D, Phillips T: A CT-BASED COMPUTERIZED TREATMENT PLANNING SYSTEM FOR I-125 STEREOTACTIC BRAIN IMPLANTS. International Journal of Radiation Oncology Biology Physics 1990,18(2):445-454. 10.1016/0360-3016(90)90114-Y
33.
Zamorano L, Dujovny M, Malik G, Yakar D, Mehta B: MULTIPLANAR CT-GUIDED STEREOTAXIS AND I125 INTERSTITIAL RADIOTHERAPY - IMAGE-GUIDED TUMOR VOLUME ASSESSMENT, PLANNING, DOSIMETRIC CALCULATIONS, STEREOTACTIC BIOPSY AND IMPLANTATION OF REMOVABLE CATHETERS. Applied Neurophysiology 1987,50(1-6):281-286.PubMed
34.
Ahmad M, Fontenla DP, Tsao STC, Chui CS, Reiff JE, Anderson LL, Huang DYC, Schell MC: DIODE DOSIMETRY OF MODEL-6711 AND MODEL-6712 I-125 SEEDS IN A WATER PHANTOM. Medical Physics 1992,19(2):391-399. 10.1118/1.596872PubMed
35.
Dale RG: SOME THEORETICAL DERIVATIONS RELATING TO THE TISSUE DOSIMETRY OF BRACHYTHERAPY NUCLIDES, WITH PARTICULAR REFERENCE TO I125. Medical Physics 1983,10(2):176-183. 10.1118/1.595297PubMed
36.
Hartmann GH, Schlegel W, Scharfenberg H: THE 3-DIMENSIONAL DOSE DISTRIBUTION OF I-125 SEEDS IN TISSUE. Physics in Medicine and Biology 1983,28(6):693-699. 10.1088/0031-9155/28/6/009PubMed
37.
Krishnaswamy V: DOSE TABLES FOR I125 SEED IMPLANTS. Radiology 1979,132(3):727-730.PubMed
38.
Mainegra E, Capote R, Lopez E: Dose rate constants for I-125, Pd-103, Ir-192 and Yb-169 brachytherapy sources: an EGS4 Monte Carlo study. Physics in Medicine and Biology 1998,43(6):1557-1566. 10.1088/0031-9155/43/6/014PubMed
39.
Mobit P, Badragan I: An evaluation of the AAPM-TG43 dosimetry protocol for I-125 brachytherapy seed. Physics in Medicine and Biology 2004.,49(14): DOI 10.1088/0031-9155/1049/1014/1010PII S0031-9155(1004)72823-72827
40.
Rodriguez EAV, Alcon EPQ, Rodriguez ML, Gutt F, de Almeida E: Dosimetric parameters estimation using PENELOPE Monte-Carlo simulation code: Model 6711 a I-125 brachytherapy seed. Applied Radiation and Isotopes 2005,63(1):41-48. 10.1016/j.apradiso.2005.02.004PubMed
41.
Anderson LL, Harrington PJ, Osian AD, Arbit E, Leibel SA, Malkin MG: A VERSATILE METHOD FOR PLANNING STEREOTAXIC BRAIN IMPLANTS. Medical Physics 1993,20(5):1457-1464. 10.1118/1.597109PubMed
42.
Kall BA, Kelly PJ, Stiving SO, Goerss SJ: Preoperative computer-assisted simulation of interstitial iodine-125 source placements into CNS lesion volumes. Stereotactic and Functional Neurosurgery 1992,59(1-4):205.
43.
Bernstein M, Lumley M, Davidson G, Laperriere N, Leung P: INTRACRANIAL ARTERIAL-OCCLUSION ASSOCIATED WITH HIGH-ACTIVITY I-125 BRACHYTHERAPY FOR GLIOBLASTOMA. J Neuro-Oncol 1993,17(3):253-260. 10.1007/BF01049980
44.
Leibel S, Gutin P, Wara W, Silver P, Hannigan J, Lamb S, Weaver K, Phillips T: SURVIVAL AND QUALITY OF LIFE FOLLOWING INTERSTITIAL IMPLANTATION OF REMOVABLE HIGH-ACTIVITY IODINE-125 SOURCES FOR RECURRENT MALIGNANT GLIOMAS. International Journal of Radiation Oncology, Biology, Physics 1988,15(SUPPL. 1):155-156.
45.
Leibel SA, Gutin PH, Wara WM, Silver PS, Larson DA, Edwards MSB, Lamb SA, Ham B, Weaver KA, Barnett C, et al.: SURVIVAL AND QUALITY OF LIFE AFTER INTERSTITIAL IMPLANTATION OF REMOVABLE HIGH-ACTIVITY I-125 SOURCES FOR THE TREATMENT OF PATIENTS WITH RECURRENT MALIGNANT GLIOMAS. International Journal of Radiation Oncology Biology Physics 1989,17(6):1129-1139. 10.1016/0360-3016(89)90518-X
46.
Willis BK, Heilbrun MP, Sapozink MD, McDonald PR: STEREOTACTIC INTERSTITIAL BRACHYTHERAPY OF MALIGNANT ASTROCYTOMAS WITH REMARKS ON POSTIMPLANTATION COMPUTED TOMOGRAPHIC APPEARANCE. Neurosurgery 1988,23(3):348-354. 10.1227/00006123-198809000-00011PubMed
47.
Wright DC, Findlay P, Rosenow U, Orr K, Miller R, Harrington F, Kinsella T: IODINE-125 INTERSTITIAL BRACHYTHERAPY FOR PRIMARY MALIGNANT BRAIN TUMORS A PHASE I-II STUDY. International Journal of Radiation Oncology, Biology, Physics 1987,13(SUPPL. 1):148-149.
48.
Schupak KD, Fass D, Malkin M, Arbit E, Anderson L, Lindsley K, Leibel S: RELATIONSHIP OF THE PATTERNS OF RECURRENCE TO THE TECHNICAL ACCURACY OF STEREOTACTIC INTERSTITIAL IMPLANTATION FOR HIGH GRADE GLIOMAS. International Journal of Radiation Oncology, Biology, Physics 1991,21(SUPPL. 1):221-222.
49.
Eddy M, Deutsch M, Selker R: QUALITY ASSURANCE FOR IODINE-125 BRAIN IMPLANTS PROGRAM DESCRIPTION AND PRELIMINARY RESULTS. Medical Physics (Woodbury) 1991,18(3):605.
50.
Dale RG: THE APPLICATION OF THE LINEAR-QUADRATIC DOSE-EFFECT EQUATION TO FRACTIONATED AND PROTRACTED RADIOTHERAPY. British Journal of Radiology 1985,58(690):515-528. 10.1259/0007-1285-58-690-515PubMed
51.
Dale RG: RADIOBIOLOGICAL ASSESSMENT OF PERMANENT IMPLANTS USING TUMOR REPOPULATION FACTORS IN THE LINEAR-QUADRATIC MODEL. British Journal of Radiology 1989,62(735):241-244. 10.1259/0007-1285-62-735-241PubMed
52.
Dale RG, Jones B, Coles IP: EFFECT OF TUMOR SHRINKAGE ON THE BIOLOGICAL EFFECTIVENESS OF PERMANENT BRACHYTHERAPY IMPLANTS. British Journal of Radiology 1994,67(799):639-645. 10.1259/0007-1285-67-799-639PubMed
53.
Gaspar LE, Zamorano LJ, Shamsa F, Fontanesi J, Ezzell GE, Yakar DA: Permanent (125)iodine implants for recurrent malignant gliomas. International Journal of Radiation Oncology Biology Physics 1999,43(5):977-982. 10.1016/S0360-3016(98)00494-5
54.
Yaes RJ: Late normal tissue injury from permanent interstitial implants. International Journal of Radiation Oncology Biology Physics 2001,49(4):1163-1169. 10.1016/S0360-3016(00)01425-5
55.
Julow J, Szeifert GT, Balint K, Nyary I, Nemes Z: The role of microglia/macrophage system in the tissue response to I-125 interstitial brachytherapy of cerebral gliomas. Neurological Research 2007,29(3):233-238. 10.1179/016164107X158875PubMed
56.
Janzer RC, Kleihues P, Ostertag CB: Early and Late Effects on the Normal Dog Brain of Permanent Interstitial Ir-192 Irradiation. Acta Neuropathol 1986,70(2):91-102. 10.1007/BF00691426PubMed
57.
Lehnert S, Reniers B, Verhaegen F: Relative biologic effectiveness in terms of tumor response of I-125 implants compared with Co-60 gamma rays. International Journal of Radiation Oncology Biology Physics 2005,63(1):224-229. 10.1016/j.ijrobp.2005.05.009
58.
Ling CC, Li WX, Anderson LL: THE RELATIVE BIOLOGICAL EFFECTIVENESS OF I-125 AND PD-103. International Journal of Radiation Oncology Biology Physics 1995,32(2):373-378. 10.1016/0360-3016(95)00530-C
59.
Zeitz L, Kim SH, Kim JH: RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF X-RAYS SIMULATING RADIATION FROM ENCAPSULATED I125 SOURCES. Radiation Research 1976,67(3):549-549.
60.
Da Silva VF, Gutin PH, Deen DF, Weaver KA: RELATIVE BIOLOGICAL EFFECTIVENESS OF IODINE-125 SOURCES IN A MURINE BRACHYTHERAPY MODEL. International Journal of Radiation Oncology, Biology, Physics 1984,10(11):2109-2112. 10.1016/0360-3016(84)90209-8PubMed
61.
Siddiqi SN, Provias J, Laperriere N, Bernstein M: Effects of iodine-125 brachytherapy on the proliferative capacity and histopathological features of glioblastoma recurring after initial therapy. Neurosurgery 1997,40(5):910-917. 10.1097/00006123-199705000-00005PubMed
62.
Cron GO, Beghein N, Crokart N, Chavee E, Bernard S, Vynckier S, Scalliet P, Gallez B: Changes in the tumor microenvironment during low-dose-rate permanent seed implantation iodine-125 brachytherapy. International Journal of Radiation Oncology Biology Physics 2005,63(4):1245-1251. 10.1016/j.ijrobp.2005.07.971
63.
Julow J, Szeifert GT, Balint K, Nyary I, Nemes Z: Tissue response to iodine-125 interstitial brachytherapy of cerebral gliomas. Prog Neurol Surg 2007, 20: 312-323.PubMed
64.
Fike JR, Cann CE, Bernstein M, Davis RL, Phillips TL, Gutin PH, Weaver KA: RADIATION-DAMAGE TO THE CANINE BRAIN AFTER I-125 IMPLANTATION. Radiation Research 1982,91(2):370-370.
65.
Kunz M, Thon N, Eigenbrod S, Hartmann C, Geisler J, Kretzschmar H, von Deimling A, Popperl G, Tonn J, Kreth F: Hot Spots in 18 Fet-Pet Delineate Malignant Tumor Parts within Suspected Who Grade Ii Glioma. Neuro-Oncology 2010, 12: 12-12.
66.
Kunz M, Thon N, Eigenbrod S, Hartmann C, Egensperger R, Herms J, Geisler J, la Fougere C, Lutz J, Linn J, et al.: Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas. Neuro Oncol 2011,13(3):307-316. 10.1093/neuonc/noq196PubMedCentralPubMed
67.
Kreth FW, Faist M, Grau S, Ostertag CB: Interstitial I-125 radiosurgery of supratentorial De Novo WHO grade 2 astrocytorna and oligoastrocytorna in adults - Long-term results and prognostic factors. Cancer 2006,106(6):1372-1381. 10.1002/cncr.21750PubMed
68.
Kreth FW, Faist M, Warnke PC, Rossner R, Volk B, Ostertag CB: INTERSTITIAL RADIOSURGERY OF LOW-GRADE GLIOMAS. J Neurosurg 1995,82(3):418-429. 10.3171/jns.1995.82.3.0418PubMed
69.
Findlay PA, Wright DC, Harrington FS, Miller RW, Glatstein E: IODINE-125 INTERSTITIAL BRACHYTHERAPY FOR PRIMARY MALIGNANT BRAIN TUMORS TECHNICAL ASPECTS OF TREATMENT PLANNING AND IMPLANTATION METHODS. International Journal of Radiation Oncology, Biology, Physics 1984,10(SUPPL. 2):93-94.
70.
Gutin PH, Phillips TL, Wara WM, Leibel SA, Hosobuchi Y, Levin VA, Weaver KA, Lamb S: BRACHYTHERAPY OF RECURRENT MALIGNANT BRAIN-TUMORS WITH REMOVABLE HIGH-ACTIVITY I125 SOURCES. J Neurosurg 1984,60(1):61-68. 10.3171/jns.1984.60.1.0061PubMed
71.
Julow J, Major T, Emri M, Valalik I, Sagi S, Mangel L, Nemeth G, Tron L, Varallyay G, Solymosi D, et al.: The application of image fusion in stereotactic brachytherapy of brain tumours. Acta Neurochir 2000,142(11):1253-1258. 10.1007/s007010070022PubMed
72.
Peraud A, Goetz C, Siefert A, Tonn JC, Kreth FW: Interstitial iodine-125 radiosurgery alone or in combination with microsurgery for pediatric patients with eloquently located low-grade glioma: a pilot study. Childs Nervous System 2007,23(1):39-46.
73.
Ten Haken RK, Diaz RF, McShan DL, Fraass BA, Taren JA, Hood TW: FROM MANUAL TO 3-D COMPUTERIZED TREATMENT PLANNING FOR IODINE-125 STEREOTACTIC BRAIN IMPLANTS. International Journal of Radiation Oncology, Biology, Physics 1988,15(2):467-480. 10.1016/S0360-3016(98)90032-3PubMed
74.
Viola A, Major T, Julow J: The importance of postoperative CT image fusion verification of stereotactic interstitial irradiation for brain tumors. International Journal of Radiation Oncology Biology Physics 2004,60(1):322-328. 10.1016/j.ijrobp.2004.04.045
75.
Knuefermann H, Wannenmacher M, Sommerkamp H, Fiedler L, Brobmann G: INDICATIONS AND LIMITS OF INTERSTITIAL RADIO THERAPY WITH IODINE-125 SEEDS. J Cancer Res Clin 1984,107(SUPPL):S60.
76.
Loeffler JS, Kooy HM, Wen PY, Fine HA, Cheng CW, Mannarino EG, Tsai JS, Alexander E: THE TREATMENT OF RECURRENT BRAIN METASTASES WITH STEREOTACTIC RADIOSURGERY. Journal of Clinical Oncology 1990,8(4):576-582.PubMed
77.
Healey EA, Shamberger RC, Grier HE, Loeffler JS, Tarbell NJ: A 10-YEAR EXPERIENCE OF PEDIATRIC BRACHYTHERAPY. International Journal of Radiation Oncology Biology Physics 1995,32(2):451-455. 10.1016/0360-3016(95)00520-9
78.
Stowe SM, Littman P, Wara W, Raney RB, Tefft M: THE USE OF IMPLANTATION IN CHILDHOOD TUMORS - THE EXPERIENCE OF CHILDRENS CANCER STUDY-GROUP MEMBER INSTITUTIONS. American Journal of Clinical Oncology-Cancer Clinical Trials 1982,5(2):129-129.
79.
Bernstein M, Laperriere N, Glen J, Leung P, Thomason C, Landon AE: BRACHYTHERAPY FOR RECURRENT MALIGNANT ASTROCYTOMA. International Journal of Radiation Oncology Biology Physics 1994,30(5):1213-1217.
80.
Frank F, Fabrizi AP, Gaist G, Frankricci R, Piazzi M, Spagnolli F: LATE CONSIDERATIONS IN THE TREATMENT OF LOW-GRADE MALIGNANCY CEREBRAL-TUMORS WITH I-125 BRACHYTHERAPY. Applied Neurophysiology 1987,50(1-6):302-309.PubMed
81.
Larson DA, Gutin PH, Leibel SA, Phillips TL, Sneed PK, Wara WM: STEREOTAXIC IRRADIATION OF BRAIN-TUMORS. Cancer 1990,65(3):792-799. 10.1002/1097-0142(19900201)65:3+<792::AID-CNCR2820651327>3.0.CO;2-PPubMed
82.
Voges J, Gaus C, Schlegel W, Pastyr O, Wowra B, Sturm V: INTERSTITIAL IRRADIATION OF A LARGE, LOW-GRADE EPENDYMOMA WITH STEREOTAXICALLY IMPLANTED I-125 SEEDS. Acta Neurochir 1993,122(1-2):127-129. 10.1007/BF01446999PubMed
83.
Mundinger F, Braus DF, Krauss JK, Birg W: LONG-TERM OUTCOME OF 89 LOW-GRADE BRAIN-STEM GLIOMAS AFTER INTERSTITIAL RADIATION-THERAPY. J Neurosurg 1991,75(5):740-746. 10.3171/jns.1991.75.5.0740PubMed
84.
Julow J, Viola A, Major T, Valalik I, Sagi S, Mangel L, Kovacs BR, Repa I, Bajzik G, Zoltan TN, et al.: Iodine-125 brachytherapy of brain stem tumors. Strahlenther Onkol 2004,180(7):449-454.PubMed
85.
Wowra B, Schmitt HP, Sturm V: INCIDENCE OF LATE RADIATION NECROSIS WITH TRANSIENT MASS EFFECT AFTER INTERSTITIAL LOW-DOSE RATE RADIOTHERAPY FOR CEREBRAL GLIOMAS. Acta Neurochir 1989,99(3-4):104-108. 10.1007/BF01402316PubMed
86.
Julow J, Kolumban Z, Viola A, Major T, Kolumban G: Prediction of volumetric change in the "triple ring" caused by glioma I-125 brachytherapy. Neuro-Oncology 2008,10(4):583-592. 10.1215/15228517-2008-027PubMedCentralPubMed
87.
Voges J, Herholz K, Holzer T, Wurker M, Bauer B, Pietrzyk U, Treuer H, Schroder R, Sturm V, Heiss WD: C-11-methionine and F-18-2-fluorodeoxy-glucose positron emission tomography: A tool for diagnosis of cerebral glioma and monitoring after brachytherapy with I-125 seeds. Stereotactic and Functional Neurosurgery 1997,69(1-4):129-135. 10.1159/000099864PubMed
88.
Wurker M, Herholz K, Voges J, Pietrzyk U, Treuer H, Bauer B, Sturm V, Heiss WD: Glucose consumption and methionine uptake in low-grade gliomas after iodine-125 brachytherapy. European Journal of Nuclear Medicine 1996,23(5):583-586. 10.1007/BF00833397PubMed
89.
Aiken AH, Chang SM, Larson D, Butowski N, Cha S: LONGITUDINAL MAGNETIC RESONANCE IMAGING FEATURES OF GLIOBLASTOMA MULTIFORME TREATED WITH RADIOTHERAPY WITH OR WITHOUT BRACHYTHERAPY. International Journal of Radiation Oncology Biology Physics 2008,72(5):1340-1346. 10.1016/j.ijrobp.2008.02.078
90.
Aarsen FK, Paquier PF, Reddingius RE, Streng IC, Arts WF, Evera-Preesman M, Catsman-Berrevoets CE: Functional outcome after low-grade astrocytoma treatment in childhood. Cancer 2006,106(2):396-402. 10.1002/cncr.21612PubMed
91.
Steinbok P: Management and outcome of low-grade astrocytomas of the midline in children: A retrospective review. Neurosurgery 1994,35(2):342-343.PubMed
92.
Sutton LN, Molloy PT, Sernyak H, Goldwein J, Phillips PL, Rorke LB, Moshang T Jr, Lange B, Packer RJ: Long-term outcome of hypothalamic/chiasmatic astrocytomas in children treated with conservative surgery. J Neurosurg 1995,83(4):583-589. 10.3171/jns.1995.83.4.0583PubMed
93.
Etou A, Mundinger F, Mohadjer M, Birg W: STEREOTACTIC INTERSTITIAL IRRADIATION OF DIENCEPHALIC TUMORS WITH IR-192 AND I-125 - 10 YEARS FOLLOW-UP AND COMPARISON WITH OTHER TREATMENTS. Childs Nervous System 1989,5(3):140-143. 10.1007/BF00272114
94.
Herrera EJ, Viano JC, Gomez JM, Surur A, Suarez JC: Interstitial stereotactic radiosurgery of pilocytic astrocytomas in paediatric patients. Acta Neurochir 2007,149(9):887-896. 10.1007/s00701-007-1237-7PubMed
95.
Ostertag CB, Kreth FW: I-125 INTERSTITIAL IRRADIATION FOR CEREBRAL GLIOMAS. Acta Neurochir 1992,119(1-4):53-61. 10.1007/BF01541782PubMed
96.
Kreth FW, Faist M, Rossner R, Birg W, Volk B, Ostertag CB: The risk of interstitial radiotherapy of low-grade gliomas. Radiotherapy and Oncology 1997,43(3):253-260. 10.1016/S0167-8140(97)01948-8PubMed
97.
Vitaz TW, Warnke PC, Tabar V, Gutin PH: Brachytherapy for brain tumors. J Neurooncol 2005,73(1):71-86. 10.1007/s11060-004-2352-4PubMed
98.
Julow J, Viola A, Balint K, Szeifert GT: Image fusion-guided stereotactic iodine-125 interstitial irradiation of inoperable and recurrent gliomas. Prog Neurol Surg 2007, 20: 303-311.PubMed
99.
Kreth FW, Faist M, Rossner R, Volk B, Ostertag CB: Supratentorial world health organization grade 2 astrocytomas and oligoastrocytomas - A new pattern of prognostic factors. Cancer 1997,79(2):370-379. 10.1002/(SICI)1097-0142(19970115)79:2<370::AID-CNCR21>3.0.CO;2-XPubMed
100.
Kreth FW, Warnke PC, Ostertag CB: INTERSTITIAL RADIOSURGERY IN TREATMENT OF LOW-GRADE GLIOMAS. Nervenarzt 1993,64(10):633-639.PubMed
101.
Mehrkens JH, Kreth FW, Muacevic A, Ostertag CB: Long term course of WHO grade II astrocytomas of the Insula of Reil after I-125 interstitial irradiation. J Neurol 2004,251(12):1455-1464. 10.1007/s00415-004-0561-6PubMed
102.
Schnell O, Scholler K, Ruge M, Siefert A, Tonn JC, Kreth FW: Surgical resection plus stereotactic I-125 brachytherapy in adult patients with eloquently located supratentorial WHO grade II glioma - Feasibility and outcome of a combined local treatment concept. J Neurol 2008,255(10):1495-1502. 10.1007/s00415-008-0948-xPubMed
103.
Warnke PC, Berlis A, Weyerbrock A, Ostertag CB: Significant reduction of seizure incidence and increase of benzodiazepine receptor density after interstitial radiosurgery in low-grade gliomas. Acta Neurochir Suppl 1997, 68: 90-92.PubMed
104.
Kreth FW, Warnke PC, Ostertag CB: INTERSTITIAL IMPLANT RADIOSURGERY FOR CEREBRAL METASTASES. Acta Neurochir 1993, 112-114.
105.
Scerrati M, Montemaggi P, Iacoangeli M, Roselli R, Rossi GF: INTERSTITIAL BRACHYTHERAPY FOR LOW-GRADE CEREBRAL GLIOMAS - ANALYSIS OF RESULTS IN A SERIES OF 36 CASES. Acta Neurochir 1994,131(1-2):97-105. 10.1007/BF01401459PubMed
106.
Suchorska B, Ruge M, Treuer H, Sturm V, Voges J: Stereotactic brachytherapy of low-grade cerebral glioma after tumor resection. Neuro Oncol 2011,13(10):1133-1142. 10.1093/neuonc/nor100PubMedCentralPubMed
107.
Bernstein M, Laperriere N, Leung P, McKenzie S: INTERSTITIAL BRACHYTHERAPY FOR MALIGNANT BRAIN-TUMORS - PRELIMINARY-RESULTS. Neurosurgery 1990,26(3):371-380. 10.1227/00006123-199003000-00001PubMed
108.
Clark WC, Fontanesi J, Patterson K, Kun L, Robertson JT: CT-GUIDED STEREOTACTIC BRACHYTHERAPY WITH IODINE-125 SEEDS FOR INITIAL TREATMENT OF MALIGNANT ASTROCYTOMA AND GLIOBLASTOMA MULTIFORME. Southern Medical Journal 1991,84(9):2S42-42S43.
109.
Gutin P, Wara W, Larson D, Leibel S, Prados M, Levin V, Sneed P, Weaver K, Silver P, et al.: STEREOTAXIC INTERSTITIAL IODINE-125 BOOST IN THE INITIAL MANAGEMENT OF MALIGNANT GLIOMAS. International Journal of Radiation Oncology, Biology, Physics 1990,19(SUPPL. 1):204.
110.
Gutin PH, Leibel SA, Wara WM, Choucair A, Levin VA, Philips TL, Silver P, Dasilva V, Edwards MSB, Davis RL, et al.: RECURRENT MALIGNANT GLIOMAS - SURVIVAL FOLLOWING INTERSTITIAL BRACHYTHERAPY WITH HIGH-ACTIVITY I-125 SOURCES. J Neurosurg 1987,67(6):864-873. 10.3171/jns.1987.67.6.0864PubMed
111.
Leibel S, Gutin P, Phillips T, Wara W, Choucair A, Weaver K, Lamb S, Silver P, Barnett C: IMPROVED SURVIVAL FOLLOWING INTERSTITIAL IMPLANTATION OF REMOVABLE HIGH-ACTIVITY IODINE-125 SOURCES FOR MALIGNANT RECURRENT GLIOMAS. International Journal of Radiation Oncology, Biology, Physics 1986,12(SUPPL. 1):146.
112.
Prados MD, Gutin PH, Phillips TL, Wara WM, Sneed PK, Larson DA, Lamb SA, Ham B, Malec MK, Wilson CB: INTERSTITIAL BRACHYTHERAPY FOR NEWLY DIAGNOSED PATIENTS WITH MALIGNANT GLIOMAS - THE UCSF EXPERIENCE. International Journal of Radiation Oncology Biology Physics 1992,24(4):593-597. 10.1016/0360-3016(92)90703-K
113.
Scharfen CO, Sneed PK, Wara WM, Larson DA, Phillips TL, Weaver KA, Prados MD, Gutin PH: STEREOTAXIC IODINE-125 BRAIN IMPLANTS FOR MALIGNANT GLIOMAS. International Journal of Radiation Oncology, Biology, Physics 1991,21(SUPPL. 1):119.
114.
Sneed PK, Gutin PH, Stauffer PR, Phillips TL, Prados MD, Weaver KA, Suen S, Lamb SA, Ham B, Ahn DK, et al.: THERMORADIOTHERAPY OF RECURRENT MALIGNANT BRAIN-TUMORS. International Journal of Radiation Oncology Biology Physics 1992,23(4):853-861. 10.1016/0360-3016(92)90659-6
115.
Yakar D, Zamorano L, Dujovny M, Sheehan M, Kim JH: Interstitial iodine-125 irradiation for malignant brain tumors: Advantage of permanent implant (PI) over temporary implants (TI). International Journal of Radiation Oncology Biology Physics 1992,24(SUPPL. 1):143.
116.
Fernandez P, Zamorano L, Gaspar L, Yakar D, Heilbrun LK: Permanent 125I implant therapy with concurrent external beam radiation in the up-front treatment of malignant gliomas. Stereotactic and Functional Neurosurgery 1994,63(1-4):287-288.
117.
Fernandez PM, Zamorano L, Yakar D, Gaspar L, Warmelink C: PERMANENT I-125 IMPLANTS IN THE UP-FRONT TREATMENT OF MALIGNANT GLIOMAS. Neurosurgery 1995,36(3):467-473. 10.1227/00006123-199503000-00004PubMed
118.
Fontanesi J, Clark WC, Weir A, Barry A, Kumar P, Miller A, Eddy T, Tai D, Kun LE: INTERSTITIAL I-125 AND CONCOMITANT CISPLATIN FOLLOWED BY HYPERFRACTIONATED EXTERNAL-BEAM IRRADIATION FOR MALIGNANT SUPRATENTORIAL GLIOMA - PRELIMINARY EXPERIENCE AT THE UNIVERSITY-OF-TENNESSEE, MEMPHIS. American Journal of Clinical Oncology-Cancer Clinical Trials 1993,16(5):412-417.
119.
Gaspar L, Zamorano L, Garcia L, Shamsa F, Warmelink C, Yakar D: Malignant gliomas: Permanent iodine-125 implants. International Journal of Radiation Oncology Biology Physics 1994,30(SUPPL 1):295.
120.
Schwarz SB, Siefert A, Ganswindt U, Kunz M, Kreth FW, Tonn JC, Belka C: The combination of percutaneous radiotherapy and (125)iodine-seed-implantation within the framework of multi model therapy concepts for cerebral tumours. Strahlentherapie Und Onkologie 2009, 185: 84-84.
121.
Videtic GMM, Gaspar LE, Zamorano L, Fontanesi J, Levin KJ, Kupsky WJ, Tekyi-Mensah S: Use of the RTOG recursive partitioning analysis to validate the benefit of iodine-125 implants in the primary treatment of malignant gliomas. International Journal of Radiation Oncology Biology Physics 1999,45(3):687-692. 10.1016/S0360-3016(99)00244-8
122.
Videtic GMM, Gaspar LE, Zamorano L, Stitt LW, Fontanesi J, Levin KJ: Implant volume as a prognostic variable in brachytherapy decision-making for malignant gliomas stratified by the RTOG recursive partitioning analysis. International Journal of Radiation Oncology Biology Physics 2001,51(4):963-968. 10.1016/S0360-3016(01)01746-1
123.
Zamorano L, Gaspar L, Garcia L, Yakar D, Shamsa F, Buciuc R, Diaz FG: PERMANENT I-125 IMPLANT IN PRIMARY MALIGNANT GLIOMA. J Neurosurg 1995,82(2):A350-A350.
124.
Zamorano L, Li QH, Tekyi-Mensah S, Gaspar L, Fontanesi J, Levin K: Permanent iodine-125 interstitial radiation therapy in the treatment of non-glioblastoma multiforme high-grade gliomas. Stereotactic and Functional Neurosurgery 2003,81(1-4):10-17. 10.1159/000075098PubMed
125.
Hitchon PW, Vangilder JC, Wen BC, Jani S, Wetjen B, Sawin PD: Brachytherapy in malignant glioma. Stereotactic and Functional Neurosurgery 1994,63(1-4):286-287.
126.
Ryken TC, Hitchon PW, Vangilder JC, Wen BC, Jani S: Interstitial brachytherapy versus cytoreductive surgery in recurrent malignant glioma. Stereotactic and Functional Neurosurgery 1994,63(1-4):241-245. 10.1159/000100320PubMed
127.
Malkin MG, Arbit E, Fass DE, Anderson LL, Osian A, Rosenblum MK, Shapiro JR, Leibel SA, Shapiro WR: STEREOTAXIC IMPLANTATION OF REMOVABLE HIGH-ACTIVITY IODINE-125 SOURCES FOR THE TREATMENT OF MALIGNANT GLIOMA. Neurology 1989,39(3 SUPPL. 1):263.
128.
Halligan JB, Stelzer KJ, Rostomily RC, Spence AM, Griffin TW, Berger MS: Operation and permanent low activity I-125 brachytherapy for recurrent high-grade astrocytomas. International Journal of Radiation Oncology Biology Physics 1996,35(3):541-547. 10.1016/S0360-3016(96)80017-4
129.
Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, Sabel MC, Koeppen S, Ketter R, Meyermann R, et al.: NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol 2009,27(35):5874-5880. 10.1200/JCO.2009.23.6497PubMed
130.
Chen AM, Chang S, Pouliot J, Sneed PK, Prados MD, Lamborn KR, Malec MK, McDermott MW, Berger MS, Larson DA: Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiforme. International Journal of Radiation Oncology Biology Physics 2007, 69: 825-830. 10.1016/j.ijrobp.2007.03.061
131.
Darakchiev BJ, Albright RE, Breneman JC, Warnick RE: Safety and efficacy of permanent iodine-125 seed implants and carmustine wafers in patients with recurrent glioblastoma multiforme. J Neurosurg 2008,108(2):236-242. 10.3171/JNS/2008/108/2/0236PubMed
132.
Keole S, Martinez J, Levin KJ, Frazier AJ, Zamorano L, Sloan A, Forman JD, Fontanesi JN: Survival analysis of patients with Glioblastoma multiforme treated with external radiotherapy followed by gamma knife radiosurgery or permanent Iodine-125 implant boost. International Journal of Radiation Oncology Biology Physics 2001,51(3 Supplement 1):256.
133.
Larson DA, Suplica JM, Chang SM, Lamborn KR, McDermott MW, Sneed PK, Prados MD, Wara WM, Nicholas MK, Berger MS: Permanent iodine 125 brachytherapy in patients with progressive or recurrent glioblastoma multiforme. Neuro-Oncology 2004,6(2):119-126. 10.1215/S1152851703000425PubMedCentralPubMed
134.
Loeffler JS, Alexander E, Wen PY, Shea WM, Coleman CN, Kooy HM, Fine HA, Nedzi LA, Silver B, Riese NE, et al.: RESULTS OF STEREOTAXIC BRACHYTHERAPY USED IN THE INITIAL MANAGEMENT OF PATIENTS WITH GLIOBLASTOMA. J Natl Cancer I 1990,82(24):1918-1921. 10.1093/jnci/82.24.1918
135.
Loeffler JS, Wen P, Alexander E III, Shea M, Black PM: RESULTS OF STEREOTACTIC INTERSTITIAL IRRADIATION USED IN TREATMENT OF RECURRENT GLIOBLASTOMA. Neurology 1991,41(3 SUPPL. 1):411.
136.
Sneed PK, Gutin PH, Larson DA, Malec MK, Phillips TL, Prados MD, Scharfen CO, Weaver KA, Wara WM: PATTERNS OF RECURRENCE OF GLIOBLASTOMA-MULTIFORME AFTER EXTERNAL IRRADIATION FOLLOWED BY IMPLANT BOOST. International Journal of Radiation Oncology Biology Physics 1994,29(4):719-727. 10.1016/0360-3016(94)90559-2
137.
Wen PY, Alexander E, Black PM, Fine HA, Riese N, Levin JM, Coleman CN, Loeffler JS: LONG-TERM RESULTS OF STEREOTAXIC BRACHYTHERAPY USED IN THE INITIAL TREATMENT OF PATIENTS WITH GLIOBLASTOMAS. Cancer 1994,73(12):3029-3036. 10.1002/1097-0142(19940615)73:12<3029::AID-CNCR2820731222>3.0.CO;2-4PubMed
138.
Chamberlain MC, Kormanik P: Concurrent carboplatin and iodine-125 brachytherapy for recurrent glioblastoma multiforme. Ann Neurol 1997,42(3):M152-M152.
139.
Koot RW, Maarouf M, Hulshof M, Voges J, Treuer H, Koedooder C, Sturm V, Bosch DA: Brachytherapy - Results of two different therapy strategies for patients with primary glioblastoma multiforme. Cancer 2000,88(12):2796-2802. 10.1002/1097-0142(20000615)88:12<2796::AID-CNCR19>3.0.CO;2-1PubMed
140.
Patel S, Breneman JC, Warnick RE, Albright RE, Tobler WD, van Loveren HR, Tew JM: Permanent iodine-125 interstitial implants for the treatment of recurrent glioblastoma multiforme. Neurosurgery 2000,46(5):1123-1128. 10.1097/00006123-200005000-00019PubMed
141.
Sneed PK, Prados MD, McDermott MW, Larson DA, Malec MK, Lamborn KR, Davis RL, Weaver KA, Wara WM, Phillips TL, et al.: LARGE EFFECT OF AGE ON THE SURVIVAL OF PATIENTS WITH GLIOBLASTOMA TREATED WITH RADIOTHERAPY AND BRACHYTHERAPY ROOST. Neurosurgery 1995,36(5):898-903. 10.1227/00006123-199505000-00002PubMed
142.
Suplica JM, Berger MS, McDermott MW, Chang SM, Prados MD, Sneed PK, Tsao MN, Wara WM, Larson DA: Total resection and permanent high-dose I-125 brachytherapy for recurrent or progressive glioblastoma. International Journal of Radiation Oncology Biology Physics 1999,45(3 SUPPL.):321.
143.
Heideman RL, Douglass EC, Krance RA, Fontanesi J, Langston JA, Sanford RA, Kovnar EH, Ochs J, Kuttesch J, Jenkins JJ, et al.: HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS BONE-MARROW RESCUE FOLLOWED BY INTERSTITIAL AND EXTERNAL-BEAM RADIOTHERAPY IN NEWLY-DIAGNOSED PEDIATRIC MALIGNANT GLIOMAS. Journal of Clinical Oncology 1993,11(8):1458-1465.PubMed
144.
Kitchen ND, Hughes SW, Taub NA, Sofat A, Beaney RP, Thomas DGT: SURVIVAL FOLLOWING INTERSTITIAL BRACHYTHERAPY FOR RECURRENT MALIGNANT GLIOMA. J Neuro-Oncol 1994,18(1):33-39. 10.1007/BF01324601
145.
Sneed PK, Gutin PH, Prados MD, Phillips TL, Weaver KA, Wara WM, Larson DA: BRACHYTHERAPY OF BRAIN-TUMORS. Stereotactic and Functional Neurosurgery 1992,59(1-4):157-165. 10.1159/000098934PubMed
146.
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJB, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, et al.: Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009,10(5):459-466. 10.1016/S1470-2045(09)70025-7PubMed
147.
Combs S, Debus J, Schulz-Ertner D: Radiotherapeutic alternatives for previously irradiated recurrent gliomas. BMC Cancer 2007, 7: 167. 10.1186/1471-2407-7-167PubMedCentralPubMed
148.
Chavantes MC, Zamorano L, Dujovny M, Milik G, Ausman JI: A NEW APPROACH FOR BRAIN METASTASES FROM LUNG CANCER IMAGE-GUIDED STEREOTAXIS AND IODINE-125 BRACHYTHERAPY. Chest 1988,94(1 SUPPL):85S.
149.
Ruge MI, Kocher M, Maarouf M, Hamisch C, Treuer H, Voges J, Sturm V: Comparison of Stereotactic Brachytherapy ((125)Iodine Seeds) with Stereotactic Radiosurgery (LINAC) for the Treatment of Singular Cerebral Metastases. Strahlentherapie Und Onkologie 2011,187(1):7-14. 10.1007/s00066-010-2168-4PubMed
150.
Ostertag CB, Kreth FW: INTERSTITIAL I-125 RADIOSURGERY FOR CEREBRAL METASTASES. British Journal of Neurosurgery 1995,9(5):593-603. 10.1080/02688699550040873PubMed
151.
Schulder M, Black PM, Shrieve DC, Alexander E, Loeffler JS: Permanent low-activity iodine-125 implants for cerebral metastases. J Neuro-Oncol 1997,33(3):213-221. 10.1023/A:1005798027813
152.
Alesch F, Hawliczek R, Koos WT: Interstitial irradiation of brain metastases. Acta Neurochirurgica Supplement; Stereotactic neuro-radio-surgery 1995, 29-34.
153.
Huang K, Sneed PK, Berger MS, Kunwar S, Larson DA, Wara WM, McDermott MW: Permanent iodine-125 brachytherapy for brain metastasis resection cavities. International Journal of Radiation Oncology Biology Physics 2002,54(2 Supplement):238.
154.
Ruge MI, Suchorska B, Maarouf M, Runge M, Treuer H, Voges J, Sturm V: Stereotactic (125)Iodine Brachytherapy for the Treatment of Singular Brain Metastases: Closing a Gap? Neurosurgery 2011,68(5):1209-1218.PubMed
155.
Dagnew E, Kanski J, McDermott MW, Sneed PK, McPherson C, Breneman JC, Warnick RE: Management of newly diagnosed single brain metastasis using resection and permanent iodine-125 seeds without initial whole-brain radiotherapy: a two institution experience. Neurosurg Focus 2007,22(3):E3.PubMed
156.
Huang K, Sneed PK, Kunwar S, Kragten A, Larson DA, Berger MS, Chan A, Pouliot J, McDermott MW: Surgical resection and permanent iodine-125 brachytherapy for brain metastases. J Neuro-Oncol 2009,91(1):83-93. 10.1007/s11060-008-9686-2
157.
Petr MJ, McPherson CM, Breneman JC, Warnick RE: Management of newly diagnosed single brain metastasis with surgical resection and permanent I-125 seeds without upfront whole brain radiotherapy. J Neuro-Oncol 2009,92(3):393-400. 10.1007/s11060-009-9868-6
158.
Prados M, Leibel S, Barnett CM, Gutin P: INTERSTITIAL BRACHYTHERAPY FOR METASTATIC BRAIN-TUMORS. Cancer 1989,63(4):657-660. 10.1002/1097-0142(19890215)63:4<657::AID-CNCR2820630410>3.0.CO;2-QPubMed
159.
Yakar D, Zamorano L, Dujovny M, Cooper M, Grandhe R, Martin F, Sheehan M: INTERSTITIAL TEMPORARY IMPLANTATION OF HIGH ACTIVITY IODINE-125 SOURCES FOR MALIGNANT GLIOMA AND BRAIN METASTASES. International Journal of Radiation Oncology, Biology, Physics 1989,17(SUPPL. 1):228.
160.
Zamorano L, Yakar D, Dujovny M, Sheehan M, Kim J: PERMANENT I-125 IMPLANT AND EXTERNAL BEAM RADIATION-THERAPY FOR THE TREATMENT OF MALIGNANT BRAIN-TUMORS. Stereotactic and Functional Neurosurgery 1992,59(1-4):183-192. 10.1159/000098940PubMed
161.
Zamorano L, Yakar D, Dujovny M, Sheehan M, Kim JH: Interstitial temporary implantation of high-activity iodine-125 sources for malignant glioma and brain metastases. Stereotactic and Functional Neurosurgery 1992,59(1-4):182.
162.
Kreth FW, Warnke PC, Ostertag CB: STEREOTAXIC INTERSTITIAL RADIOSURGERY AND PERCUTANEOUS RADIOTHERAPY FOR TREATMENT OF CEREBRAL METASTASES. Nervenarzt 1993,64(2):108-113.PubMed
163.
Ruge MI, Kickingereder P, Grau S, Hoevels M, Treuer H, Sturm V: Stereotactic biopsy combined with stereotactic (125)iodine brachytherapy for diagnosis and treatment of locally recurrent single brain metastases. J Neurooncol 2011,105(1):109-118. 10.1007/s11060-011-0571-zPubMed
164.
Barlas O, Bayindir C, Imer M, Ayan I, Darendeliler E: Non-resective management of pineoblastoma. Minimally Invasive Neurosurgery 2000,43(3):163-170. 10.1055/s-2000-14509PubMed
165.
Maarouf M, El Majdoub F, Buhrle C, Voges J, Lehrke R, Kocher M, Hunsche S, Treuer H, Sturm V: Pineal Parenchymal Tumors Management with Interstitial Iodine-125 Radiosurgery. Strahlentherapie Und Onkologie 2010,186(3):127-134. 10.1007/s00066-010-2096-3PubMed
166.
Kumar PP, Patil AA, Leibrock LG, Chu WK, Syh HW, McCaul GF, Reeves MA: CONTINUOUS LOW-DOSE RATE BRACHYTHERAPY WITH HIGH-ACTIVITY I-125 SEEDS IN THE MANAGEMENT OF MENINGIOMAS. International Journal of Radiation Oncology Biology Physics 1993,25(2):325-328. 10.1016/0360-3016(93)90355-Y
167.
Kumar PP, Patil AA, Leibrock LG, Chu WK, Syh J, McCaul GF, Reeves MA: BRACHYTHERAPY - A VIABLE ALTERNATIVE IN THE MANAGEMENT OF BASAL MENINGIOMAS. Neurosurgery 1991,29(5):676-680. 10.1227/00006123-199111000-00006PubMed
168.
Kumar PP, Patil AA, Syh HW, Chu WK, Reeves MA: ROLE OF BRACHYTHERAPY IN THE MANAGEMENT OF THE SKULL BASE MENINGIOMA - TREATMENT OF SKULL BASE MENINGIOMAS. Cancer 1993,71(11):3726-3731. 10.1002/1097-0142(19930601)71:11<3726::AID-CNCR2820711141>3.0.CO;2-HPubMed
169.
Obasi PC, Barnett GH, Suh JH: Brachytherapy for intracranial meningioma using a permanently implanted iodine-125 seed. Stereotactic and Functional Neurosurgery 2002,79(1):33-43. 10.1159/000069502PubMed
170.
Patil AA, Kumar P, Leibrock LG: Response of extra-axial tumors to stereotactically implanted high-activity I-125 seeds. Stereotactic and Functional Neurosurgery 1995,64(3):139-152.PubMed
171.
Vuorinen V, Heikkonen J, Brander A, Setala K, Sane T, Randell T, Paetau A, Pohjola J, Mantyla M, Jaaskelainen J: Interstitial radiotherapy of 25 parasellar/clival meningiomas and 19 meningiomas in the elderly - Analysis of short-term tolerance and responses. Acta Neurochir 1996,138(5):495-508. 10.1007/BF01411167PubMed
172.
Kumar PP, Good RR, Cox TA, Leibrock LG, Skultety FM: REVERSAL OF VISUAL IMPAIRMENT AFTER INTERSTITIAL IRRADIATION OF PITUITARY-TUMOR. Neurosurgery 1986,18(1):82-84. 10.1227/00006123-198601000-00014PubMed
173.
Kumar PP, Good RR, Skultety FM, Leibrock LG, Severson GS: RADIATION-INDUCED NEOPLASMS OF THE BRAIN. Cancer 1987,59(7):1274-1282. 10.1002/1097-0142(19870401)59:7<1274::AID-CNCR2820590708>3.0.CO;2-HPubMed
174.
Kumar PP, Good RR, Skultety FM, Leibrock LG: LOCAL-CONTROL OF RECURRENT CLIVAL AND SACRAL CHORDOMA AFTER INTERSTITIAL IRRADIATION WITH I-125 - NEW TECHNIQUES FOR TREATMENT OF RECURRENT OR UNRESECTABLE CHORDOMAS. Neurosurgery 1988,22(3):479-483. 10.1227/00006123-198803000-00005PubMed
175.
Kumar PP: HIGH ACTIVITY IODINE-125 ENDOCURIETHERAPY FOR SKULL BASE TUMORS. International Journal of Radiation Oncology, Biology, Physics 1990,19(SUPPL. 1):226.
176.
Kumar PP, Good RR, Leibrock LG, Mawk JR, Yonkers AJ, Ogren FP: HIGH-ACTIVITY IODINE 125 ENDOCURIETHERAPY FOR RECURRENT SKULL BASE TUMORS. Cancer 1988,61(8):1518-1527. 10.1002/1097-0142(19880415)61:8<1518::AID-CNCR2820610807>3.0.CO;2-DPubMed
177.
Collins SP, Coppa ND, Zhang Y, Collins BT, McRae DA, Jean WC: CyberKnife (R) radiosurgery in the treatment of complex skull base tumors: analysis of treatment planning parameters. Radiation Oncology 2006., 1:
178.
Minniti G, Amichetti M, Enrici RM: Radiotherapy and radiosurgery for benign skull base meningiomas. Radiat Oncol 2009, 4: 42. 10.1186/1748-717X-4-42PubMedCentralPubMed
179.
El Majdoub F, Brunn A, Berthold F, Sturm V, Maarouf M: Stereotaktische interstitielle Radiochirurgie zur Behandlung des intrakraniellen Rosai-Dorfman-Syndroms. Ein neuer therapeutischer Ansatz. Strahlentherapie Und Onkologie 2009,185(2):109-112. 10.1007/s00066-009-1911-1PubMed
180.
Suarez JC, Viano JC, Zunino S, Herrera EJ, Gomez J, Tramunt B, Marengo I, Hiramatzu E, Miras M, Pena M, et al.: Management of child optic pathway gliomas: new therapeutical option. Childs Nervous System 2006,22(7):679-684. 10.1007/s00381-005-0021-3
181.
Barlas O, Bayindir C, Can M: Interstitial irradiation for craniopharyngioma. Acta Neurochir 2000,142(4):389-395. 10.1007/s007010050447PubMed
182.
Frank F, Fabrizi AP, Frank G, Fioravanti A: Stereotactic management of craniopharyngiomas. Stereotactic and Functional Neurosurgery 1995,65(1-4):176-183. 10.1159/000098691PubMed
183.
El Majdoub F, Simon T, Hoevels M, Berthold F, Sturm V, Maarouf M: Interstitial Brachytherapy using Stereotactic Implanted 125Iodine Seeds for Recurrent Medulloblastoma. Clinical Oncology, in press. Corrected Proof
184.
Chalifoux R, Elisevich K: Effect of ionizing radiation on partial seizures attributable to malignant cerebral tumors. Stereotactic and Functional Neurosurgery 1996,67(3-4):169-182.PubMed
185.
Chamberlain MC, Barba D, Kormanik P, Berson AM, Saunders WM, Shea MC: CONCURRENT CISPLATIN THERAPY AND IODINE-125 BRACHYTHERAPY FOR RECURRENT MALIGNANT BRAIN-TUMORS. Archives of Neurology 1995,52(2):162-167. 10.1001/archneur.1995.00540260066018PubMed
186.
Tacke U, Karger D, Spreer J, Berlis A, Nikkhah G, Korinthenberg R: Incidence of vasculopathy in children with hypothalamic/chiasmatic gliomas treated with brachytherapy. Childs Nervous System 2011,27(6):961-966. 10.1007/s00381-010-1370-0
187.
Bampoe J, Nag S, Leung P, Laperriere N, Bernstein M: Brain necrosis after permanent low-activity iodine-125 implants: case report and review of toxicity from focal radiation. Brain Tumor Pathol 2000,17(3):139-145. 10.1007/BF02484285PubMed
188.
Agbi CB, Bernstein M, Laperriere N, Leung P, Lumley M: PATTERNS OF RECURRENCE OF MALIGNANT ASTROCYTOMA FOLLOWING STEREOTAXIC INTERSTITIAL BRACHYTHERAPY WITH I-125 IMPLANTS. International Journal of Radiation Oncology Biology Physics 1992,23(2):321-326. 10.1016/0360-3016(92)90748-7
189.
Wara WM: RADIATION-THERAPY FOR BRAIN-TUMORS. Cancer 1985,55(9):2291-2295. 10.1002/1097-0142(19850501)55:9+<2291::AID-CNCR2820551437>3.0.CO;2-CPubMed
190.
Tihan T, Barletta J, Parney I, Lamborn K, Sneed PK, Chang S: Prognostic value of detecting recurrent glioblastoma multiforme in surgical specimens from patients after radiotherapy: should pathology evaluation atter treatment decisions? Human Pathology 2006,37(3):272-282. 10.1016/j.humpath.2005.11.010PubMed
191.
Frank F, Gaist G, Piazza G, Ricci RF, Sturiale C, Galassi E: STEREOTAXIC BIOPSY AND RADIOACTIVE IMPLANTATION FOR INTERSTITIAL THERAPY OF TUMORS OF THE PINEAL REGION. Surgical Neurology 1985,23(3):275-280. 10.1016/0090-3019(85)90095-3PubMed
192.
Houston SC, Crocker IR, Brat DJ, Olson JJ: Extraneural metastatic glioblastoma after interstitial brachytherapy. International Journal of Radiation Oncology Biology Physics 2000,48(3):831-836. 10.1016/S0360-3016(00)00662-3
193.
Correa CF, Teixeira MJ, Rogano LA, Oliveira S, Miziara M, Gusmao C, Bouza AA: 125 I brachytherapy for treatment of CNS tumors. Stereotactic and Functional Neurosurgery 1996,67(1-2):93.
194.
Leibel SA, Gutin PH, Phillips TL, Wara WM, Weaver KA, Lamb S: INTERSTITIAL IMPLANTATION OF HIGH-ACTIVITY IODINE-125 SOURCES FOR THE TREATMENT OF RECURRENT MALIGNANT BRAIN TUMORS. International Journal of Radiation Oncology, Biology, Physics 1984,10(SUPPL. 2):144-145.
195.
Leibel SA, Gutin PH, Phillips TL, Wara WM, Weaver KA, Lamb S: INTERSTITIAL BRACHYTHERAPY WITH REMOVABLE HIGH-ACTIVITY I-125 SOURCES FOR RECURRENT MALIGNANT BRAIN-TUMORS. American Journal of Clinical Oncology-Cancer Clinical Trials 1985,8(1):20-20.
196.
Vordermark D: Brachytherapy - Results of two different therapy strategies for patients with primary glioblastoma multiforme. Cancer 2001,91(6):1185-1186. 10.1002/1097-0142(20010315)91:6<1185::AID-CNCR1116>3.0.CO;2-QPubMed
197.
Rostomily RC, Halligan J, Geyer R, Stelzer K, Lindsley K, Berger MS: Permanent low-activity I-125 seed placement for the treatment of pediatric brain tumors: Preliminary experience. Pediatric Neurosurgery 2001,34(4):198-205. 10.1159/000056020PubMed
198.
Korinthenberg RND, Trippel M, Ostertag C, Nikkhah G: Long-Term Results of Brachytherapy with temporary iodine-125 Seeds in Children with low-grade gliomas. International Journal Radiation Oncology Biology Physics 2011,79(4):1131-1138. 10.1016/j.ijrobp.2009.12.040
199.
Ruge MI, Simon T, Suchorska B, Lehrke R, Hamisch C, Koerber F, Maarouf M, Treuer H, Berthold F, Sturm V, et al.: Stereotactic brachytherapy with iodine-125 seeds for the treatment of inoperable low-grade gliomas in children: long-term outcome. J Clin Oncol 2011,29(31):4151-4159. 10.1200/JCO.2011.37.3381PubMed
Metadata
Title
Iodine-125 brachytherapy for brain tumours - a review
Authors
Silke B Schwarz
Niklas Thon
Katharina Nikolajek
Maximilian Niyazi
Joerg-Christian Tonn
Claus Belka
Friedrich-Wilhelm Kreth
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2012
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/1748-717X-7-30

Other articles of this Issue 1/2012

Radiation Oncology 1/2012 Go to the issue

Research

Increased Artemis levels confer radioresistance to both high and low LET radiation exposures

Research

Image-Guided Robotic Stereotactic Radiation Therapy with Fiducial-Free Tumor Tracking for Lung Cancer

Research

Comparison of accelerated partial breast irradiation via multicatheter interstitial brachytherapy versus whole breast radiation

Research

Cleavage of ST6Gal I by Radiation-Induced BACE1 Inhibits Golgi-Anchored ST6Gal I-Mediated Sialylation of Integrin β1 and Migration in Colon Cancer Cells

Short report

MUC5B levels in submandibular gland saliva of patients treated with radiotherapy for head-and-neck cancer: A pilot study

Research

Failure patterns and survival in patients with nasopharyngeal carcinoma treated with intensity modulated radiation in Northwest China: A pilot study