Issue 9/2007
Content (8 Articles)
Leading Article
Integrated Pharmacokinetics and Pharmacodynamics in Drug Development
Jasper Dingemanse, Silke Appel-Dingemanse
Original Research Article
Phase I Evaluation of the Safety, Pharmacokinetics and Pharmacodynamics of CP-481,715
Alan T. Clucas, Ajit Shah, Yuanchao (Derek) Zhang, Vincent F. Chow, Ronald P. Gladue
Original Research Article
Pharmacokinetics and Tolerability of Duloxetine following Oral Administration to Healthy Chinese Subjects
Si Tianmei, Mary Pat Knadler, Ming T. Lim, Kwee Poo Yeo, Leyan Teng, Shu Liang, Alan X. Pan, Evelyn D. Lobo
Original Research Article
Increased Absorption of Digoxin from the Human Jejunum Due to Inhibition of Intestinal Transporter-Mediated Efflux
Svitlana Igel, Siegfried Drescher, Thomas Mürdter, Ute Hofmann, Georg Heinkele, Heike Tegude, Hartmut Glaeser, Stefanie S. Brenner, Andrew A. Somogyi, Taher Omari, Christian Schäfer, Michel Eichelbaum, Martin F. Fromm
Original Research Article
The Absolute Oral Bioavailability and Population-Based Pharmacokinetic Modelling of a Novel Dipeptidylpeptidase-IV Inhibitor, Vildagliptin, in Healthy Volunteers
Yan-Ling He, Brian M. Sadler, Ron Sabo, Sebastien Balez, Yibin Wang, Joelle Campestrini, Aziz Laurent, Monica Ligueros-Saylan, Dan Howard
Correspondence
Thiopurine Treatment in Inflammatory Bowel Disease
Sharon J. Gardiner, Evan J. Begg, Ashis Sau, Anthony Marinaki, Richard B. Gearry, Murray L. Barclay