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Published in: Lung 6/2015

01-12-2015

Clinical Features and Outcomes of Respiratory Complications in Patients with Thoracic Hyperkyphosis

Authors: Seok Jeong Lee, Ji Young Chang, Yon Ju Ryu, Jin Hwa Lee, Jung Hyun Chang, Sung Shine Shim, Ji Young Hwang

Published in: Lung | Issue 6/2015

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Abstract

Introduction

There are few data about thoracic hyperkyphosis which focused on respiratory events and prognoses. We investigated the clinical features and outcomes of respiratory complications requiring hospitalization in patients with thoracic hyperkyphosis.

Methods

Following a retrospective review of the medical records between 2002 and 2011, we included 51 patients with thoracic hyperkyphosis who had visited the respiratory department due to respiratory symptoms.

Results

Of total 51 patients, 35 patients were hospitalized due to respiratory events. Among 56 total hospitalized events, acute respiratory failure (ARF) (n = 18) and exacerbation of a chronic airway disorder (n = 18) were the most common causes. Respiratory events related mortality was 13.7 % (7/51). The median value of the thoracic kyphosis angle was 89.0°. The ratio of the measured kyphosis angle to the normal value according to age and sex showed the median value of 2.38 (interquartile range 1.61–2.87). This ratio was negatively correlated with both predicted forced vital capacity (γ = −0.647, p < 0.0001) and predicted forced expiratory volume for 1 s (γ = −0.518, p = 0.008). After adjustments for age and sex, hyperkyphosis (angle ≥90°) was not found to influence the development of ARF (hazard ratio 3.2; 95 % confidence interval, 0.86–12.14; p = 0.082).

Conclusions

Patients with thoracic hyperkyphosis presenting to a respiratory department with respiratory issues commonly experienced respiratory events requiring hospitalization and had a poor prognosis. In addition, the severity of the kyphosis angle was correlated with respiratory insufficiency although it was not a risk factor for the development of ARF.
Literature
2.
go back to reference Culham EG, Jimenez HA, King CE (1994) Thoracic kyphosis, rib mobility, and lung volumes in normal women and women with osteoporosis. Spine (Phila Pa 1976) 19(11):1250–1255CrossRef Culham EG, Jimenez HA, King CE (1994) Thoracic kyphosis, rib mobility, and lung volumes in normal women and women with osteoporosis. Spine (Phila Pa 1976) 19(11):1250–1255CrossRef
3.
go back to reference Yuan N, Skaggs DL, Dorey F et al (2005) Preoperative predictors of prolonged postoperative mechanical ventilation in children following scoliosis repair. Pediatr Pulmonol 40(5):414–419. doi:10.1002/ppul.20291 CrossRefPubMed Yuan N, Skaggs DL, Dorey F et al (2005) Preoperative predictors of prolonged postoperative mechanical ventilation in children following scoliosis repair. Pediatr Pulmonol 40(5):414–419. doi:10.​1002/​ppul.​20291 CrossRefPubMed
4.
go back to reference Libby DM, Briscoe WA, Boyce B et al (1982) Acute respiratory failure in scoliosis or kyphosis: prolonged survival and treatment. Am J Med 73(4):532–538CrossRefPubMed Libby DM, Briscoe WA, Boyce B et al (1982) Acute respiratory failure in scoliosis or kyphosis: prolonged survival and treatment. Am J Med 73(4):532–538CrossRefPubMed
5.
go back to reference Buyse B, Meersseman W, Demedts M (2003) Treatment of chronic respiratory failure in kyphoscoliosis: oxygen or ventilation? Eur Respir J 22(3):525–528CrossRefPubMed Buyse B, Meersseman W, Demedts M (2003) Treatment of chronic respiratory failure in kyphoscoliosis: oxygen or ventilation? Eur Respir J 22(3):525–528CrossRefPubMed
6.
go back to reference Terry RY, Lindsay JR (2005) Essentials of Skeletal Radiology, 3rd edn. Lippincott Williams & Wilkins, Philadelphia Terry RY, Lindsay JR (2005) Essentials of Skeletal Radiology, 3rd edn. Lippincott Williams & Wilkins, Philadelphia
8.
go back to reference Cobb JR (1948) Outline for the study of scoliosis. Am Acad Orthop Surg 5:261–275 Cobb JR (1948) Outline for the study of scoliosis. Am Acad Orthop Surg 5:261–275
9.
go back to reference McMaster MJ, Singh H (1999) Natural history of congenital kyphosis and kyphoscoliosis. a study of one hundred and twelve patients. J Bone Joint Surg Am 81(10):1367–1383PubMed McMaster MJ, Singh H (1999) Natural history of congenital kyphosis and kyphoscoliosis. a study of one hundred and twelve patients. J Bone Joint Surg Am 81(10):1367–1383PubMed
10.
go back to reference Campbell RM Jr, Smith MD, Mayes TC et al (2003) The characteristics of thoracic insufficiency syndrome associated with fused ribs and congenital scoliosis. J Bone Joint Surg Am 85-a(3):399–408PubMed Campbell RM Jr, Smith MD, Mayes TC et al (2003) The characteristics of thoracic insufficiency syndrome associated with fused ribs and congenital scoliosis. J Bone Joint Surg Am 85-a(3):399–408PubMed
13.
go back to reference Christensen ST, Hartvigsen J (2008) Spinal curves and health: a systematic critical review of the epidemiological literature dealing with associations between sagittal spinal curves and health. J Manip Physiol Ther 31(9):690–714. doi:10.1016/j.jmpt.2008.10.004 CrossRef Christensen ST, Hartvigsen J (2008) Spinal curves and health: a systematic critical review of the epidemiological literature dealing with associations between sagittal spinal curves and health. J Manip Physiol Ther 31(9):690–714. doi:10.​1016/​j.​jmpt.​2008.​10.​004 CrossRef
15.
go back to reference Yagi M, Patel R, Boachie-Adjei O (2013) Complications and unfavorable clinical outcomes in obese and overweight patients treated for adult lumbar or thoracolumbar scoliosis with combined anterior/posterior surgery. J Spinal Disord Tech. doi:10.1097/BSD.0b013e3182999526 Yagi M, Patel R, Boachie-Adjei O (2013) Complications and unfavorable clinical outcomes in obese and overweight patients treated for adult lumbar or thoracolumbar scoliosis with combined anterior/posterior surgery. J Spinal Disord Tech. doi:10.​1097/​BSD.​0b013e3182999526​
16.
go back to reference Ergun P, Aydin G, Turay UY et al (2002) Short-term effect of nasal intermittent positive-pressure ventilation in patients with restrictive thoracic disease. Respiration 69(4):303–308. doi:10.1159/000063268 CrossRefPubMed Ergun P, Aydin G, Turay UY et al (2002) Short-term effect of nasal intermittent positive-pressure ventilation in patients with restrictive thoracic disease. Respiration 69(4):303–308. doi:10.​1159/​000063268 CrossRefPubMed
17.
go back to reference Gonzalez C, Ferris G, Diaz J et al (2003) Kyphoscoliotic ventilatory insufficiency: effects of long-term intermittent positive-pressure ventilation. Chest 124(3):857–862CrossRefPubMed Gonzalez C, Ferris G, Diaz J et al (2003) Kyphoscoliotic ventilatory insufficiency: effects of long-term intermittent positive-pressure ventilation. Chest 124(3):857–862CrossRefPubMed
19.
go back to reference Ghanbarzadeh M, Mehdipour A (2009) Study and influence of exercise program on respiratory function of adults with kyphosis. Acta Bioeng Biomech 11(1):11–17PubMed Ghanbarzadeh M, Mehdipour A (2009) Study and influence of exercise program on respiratory function of adults with kyphosis. Acta Bioeng Biomech 11(1):11–17PubMed
Metadata
Title
Clinical Features and Outcomes of Respiratory Complications in Patients with Thoracic Hyperkyphosis
Authors
Seok Jeong Lee
Ji Young Chang
Yon Ju Ryu
Jin Hwa Lee
Jung Hyun Chang
Sung Shine Shim
Ji Young Hwang
Publication date
01-12-2015
Publisher
Springer US
Published in
Lung / Issue 6/2015
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-015-9795-6

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