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Italian Journal of Pediatrics
Published in: Italian Journal of Pediatrics 1/2012

Open Access 01-12-2012 | Review

Clinical application of exhaled nitric oxide measurement in pediatric lung diseases

Authors: Angelo Manna, Carlo Caffarelli, Margherita Varini, Carlotta Povesi Dascola, Silvia Montella, Marco Maglione, Francesco Sperlì, Francesca Santamaria

Published in: Italian Journal of Pediatrics | Issue 1/2012

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Summary

Fractional exhaled nitric oxide (FeNO) is a non invasive method for assessing the inflammatory status of children with airway disease. Different ways to measure FeNO levels are currently available. The possibility of measuring FeNO levels in an office setting even in young children, and the commercial availability of portable devices, support the routine use of FeNO determination in the daily pediatric practice. Although many confounding factors may affect its measurement, FeNO is now widely used in the management of children with asthma, and seems to provide significantly higher diagnostic accuracy than lung function or bronchial challenge tests. The role of FeNO in airway infection (e.g. viral bronchiolitis and common acquired pneumonia), in bronchiectasis, or in cases with diffuse lung disease is less clear. This review focuses on the most recent advances and the current clinical applications of FeNO measurement in pediatric lung disease.
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Metadata
Title
Clinical application of exhaled nitric oxide measurement in pediatric lung diseases
Authors
Angelo Manna
Carlo Caffarelli
Margherita Varini
Carlotta Povesi Dascola
Silvia Montella
Marco Maglione
Francesco Sperlì
Francesca Santamaria
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2012
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/1824-7288-38-74

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