Published in:
Open Access
01-12-2005 | Hypothesis
Clade, Country and Region-specific HIV-1 Vaccines: Are they necessary?
Authors:
Karen S Slobod, Chris Coleclough, Scott A Brown, John Stambas, Xiaoyan Zhan, Sherri Surman, Bart G Jones, Amy Zirkel, Pamela J Freiden, Brita Brown, Robert Sealy, Mattia Bonsignori, Julia L Hurwitz
Published in:
AIDS Research and Therapy
|
Issue 1/2005
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Abstract
Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary.