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Open Access 01-12-2022 | Ciprofloxacin | Case report

First case of a renal cyst infection caused by Desulfovibrio: a case report and literature review

Authors: Yoshiki Okamoto, Yoei Miyabe, Momoko Seki, Yusuke Ushio, Keisuke Sato, Eri Kasama, Kenichi Akiyama, Kazunori Karasawa, Keiko Uchida, Ken Kikuchi, Kosaku Nitta, Takahito Moriyama, Junichi Hoshino

Published in: BMC Nephrology | Issue 1/2022

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Abstract

Background

Genus Desulfovibrio species is a sulphate-reducing anaerobic gram-negative rod that resides in the human oral cavity and intestinal tract. It was reported as the causative pathogen of bacteraemia and abdominal infections, but not renal cyst infection, and Desulfovibrio fairfieldensis has higher pathogenicity than other Desulfovibrio species.

Case presentation

A 63-year-old man was on haemodialysis for end-stage renal failure due to autosomal dominant polycystic kidney disease. On admission, he had a persistent high-grade fever, right lumbar back pain, and elevated C-reactive protein levels. His blood and urine cultures were negative. He received ciprofloxacin and meropenem; however, there was no clinical improvement. Contrast-enhanced computed tomography and plain magnetic resonance imaging revealed a haemorrhagic cyst at the upper pole of the right kidney. The lesion was drained. Although the drainage fluid culture was negative, D. fairfieldensis was detected in a renal cyst using a polymerase chain reaction. After the renal cyst drainage, he was treated with oral metronidazole and improved without any relapse.

Conclusions

To the best of our knowledge, this is the first reported case of a renal cyst infection with Desulfovibrio species. D. fairfieldensis is difficult to detect, and polymerase chain reaction tests can detect this bacterium and ensure better management for a successful recovery.
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Metadata
Title
First case of a renal cyst infection caused by Desulfovibrio: a case report and literature review
Authors
Yoshiki Okamoto
Yoei Miyabe
Momoko Seki
Yusuke Ushio
Keisuke Sato
Eri Kasama
Kenichi Akiyama
Kazunori Karasawa
Keiko Uchida
Ken Kikuchi
Kosaku Nitta
Takahito Moriyama
Junichi Hoshino
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Nephrology / Issue 1/2022
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/s12882-022-02803-w

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