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BMC Pulmonary Medicine

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Open Access 01-12-2024 | Chronic Obstructive Lung Disease | Research

Associations between different body mass index and lung function impairment in Chinese people aged over 40 years: a multicenter cross-sectional study

Authors: Yumeng Tang, Lan Zhang, Shuzhen Zhu, Miaoyan Shen, Maowei Cheng, Fei Peng

Published in: BMC Pulmonary Medicine | Issue 1/2024

Abstract

Objective

The aim of this study was to explore the associations between different body mass index (BMI) levels and different lung function impairment (LFI) in Chinese people aged over 40 years.

Methods

We used a multi-stage stratified cluster random sampling method to investigate 3000 residents aged over 40 years from 5 areas in Hubei province of China in 2019-20. The data on questionnaire, physical measurements, and spirometry of the participants were collected. The associations of different BMI levels with different LFI were analyzed using multivariate logistic regressions after complex weighting. The spirometry data were analyzed using one-factor analysis of variance (ANOVA), and post-hoc was performed using the least significance difference (LSD)-t test.

Results

A total of 2860 subjects were included. The prevalence (95%CI) of obstructive lung disease (OLD), restrictive lung disease (RLD), mixed lung disease (MLD), chronic obstructive pulmonary disease (COPD), COPD mild, and COPD moderate/severe/very severe were 24.1% (95% CI: 22.2–26.2), 11.6% (95% CI: 10.3–12.9), 4.0% (95% CI: 3.3–4.8), 12.6% (95% CI: 11.0-14.1), 7.2% (95% CI: 6.0-8.4), and 5.3% (95% CI: 4.3–6.4) respectively. After multivariate adjustment, the risk of OLD, COPD, and COPD mild decreased with the increment of BMI levels (both P for trend < 0.05). When compared to the normal weight group, the overweight group and obese group were at lower risk of experiencing OLD than normal group, the ORs were 0.77 (95% CI: 0.59–0.99) and 0.59 (95% CI: 0.40–0.86) respectively. The obese group was at lower risk for people with COPD mild (OR: 0.42, 95%CI: 0.21–0.85). Participants in underweight group were more likely to experience COPD and COPD moderate/severe/very severe, the ORs were 2.82 (95% CI: 1.07–7.39) and 3.89 (95% CI: 1.28–11.87) respectively.

Conclusion

Higher BMI levels were associated with an decreased risk of OLD and COPD. Obesity had a protective effect on lung function in OLD patients and COPD patients. However, there was no significant difference in RLD and MLD prevalence between different BMI groups.

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Title: Associations between different body mass index and lung function impairment in Chinese people aged over 40 years: a multicenter cross-sectional study
Authors: Yumeng Tang
Lan Zhang
Shuzhen Zhu
Miaoyan Shen
Maowei Cheng
Fei Peng
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Chronic Obstructive Lung Disease
Obstructive Lung Diseases
Spirometry
Underweight
Underweight
Overweight
Published in: BMC Pulmonary Medicine / Issue 1/2024
Electronic ISSN: 1471-2466
DOI: https://doi.org/10.1186/s12890-024-02844-x

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