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Published in: Journal of Medical Case Reports 1/2024

Open Access 18-03-2024 | Chronic Inflammatory Bowel Disease in Pediatrics | Case report

Infantile inflammatory bowel disease in three Syrian infants: a case series

Authors: Afif Alshwaiki, Ranim M. H. D. Samir Nakhal, Ali Alakbar Nahle, Hussein Hamdar, Nafiza Martini, Jaber Mahmod

Published in: Journal of Medical Case Reports | Issue 1/2024

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Abstract

Background

Inflammatory bowel diseases, consisting of Crohn’s disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders. Inflammatory bowel diseases begin rarely in infants. Approximately 25% of patients with inflammatory bowel diseases present before the age of 20 years. Very early-onset inflammatory bowel disease occurs before the age of 6 years; infantile inflammatory bowel diseases occurs before the age of 2 years, and is extremely rare in infants under 1 year of age.

Case presentation

Herein, we report a case series of 7-month-, 11-month-, and 12-month-old Syrian infants that presented with diarrhea, hematochezia, and pale appearance and were finally diagnosed with infantile inflammatory bowel disease and treated.

Conclusions

Early diagnosis and ruling out infantile inflammatory bowel diseases despite its rarity are recommended. Over and above that, new drugs such as vedolizumab, golimumab, and less invasive treatment methods should also be taken into consideration for better response and adequate remission with improved quality of life.
Literature
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go back to reference Snapper SB. Very-early-onset inflammatory bowel disease. Gastroenterol Hepatol. 2015;11(8):554–6. Snapper SB. Very-early-onset inflammatory bowel disease. Gastroenterol Hepatol. 2015;11(8):554–6.
Metadata
Title
Infantile inflammatory bowel disease in three Syrian infants: a case series
Authors
Afif Alshwaiki
Ranim M. H. D. Samir Nakhal
Ali Alakbar Nahle
Hussein Hamdar
Nafiza Martini
Jaber Mahmod
Publication date
18-03-2024

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