Skip to main content
Top
Published in: Pituitary 4/2016

01-08-2016

Chordoid glioma of the third ventricle: a patient presenting with SIADH and a review of this rare tumor

Authors: Matilde Calanchini, Simon Cudlip, Monika Hofer, James Byrne, Andrea Fabbri, Ashley Grossman

Published in: Pituitary | Issue 4/2016

Login to get access

Abstract

Introduction

Chordoid glioma of the third ventricle is a rare and recently described tumor characterized by a unique histomorphology and exclusive association with the suprasellar/third ventricular compartment. Its clinical, radiological and histological features may vary. Despite the fact that chordoid glioma is a low-grade tumor, its prognosis has been relatively poor because of its insidious presentation and the difficulty in obtaining complete surgical resection.

Materials and methods

Here, we report on a new case of chordoid glioma occurring in a 48-year-old woman, presented with hyponatremia, and on the initial work-up with a diagnosis of hyponatremia due at least in part to SIADH. We review the current literature on this rare pathology, discuss the radiological and histopathologic findings, and discuss the optimal management of chordoid glioma in general.

Conclusion

Based on this new case and the previous literature reports, we suggest that chordoid glioma should be included in the differential diagnosis of uncommon masses of the third ventricle, especially in middle-aged women, and we emphasize current management guidelines.
Literature
1.
go back to reference Brat DJ, Scheithauer BW, Staugaitis SM, Cortez SC, Brecher K, Burger PC (1998) Third ventricular chordoid glioma: a distinct clinicopathologic entity. J Neuropathol Exp Neurol 57(3):283–290CrossRefPubMed Brat DJ, Scheithauer BW, Staugaitis SM, Cortez SC, Brecher K, Burger PC (1998) Third ventricular chordoid glioma: a distinct clinicopathologic entity. J Neuropathol Exp Neurol 57(3):283–290CrossRefPubMed
2.
go back to reference Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumors of the central nervous system. Acta Neuropathol 114(2):97–109CrossRefPubMedPubMedCentral Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumors of the central nervous system. Acta Neuropathol 114(2):97–109CrossRefPubMedPubMedCentral
3.
go back to reference Leeds NE, Lang FF, Ribalta T, Sawaya R, Fuller GN (2006) Origin of chordoid glioma of the third ventricle. Arch Pathol Lab Med 130(4):460–464PubMed Leeds NE, Lang FF, Ribalta T, Sawaya R, Fuller GN (2006) Origin of chordoid glioma of the third ventricle. Arch Pathol Lab Med 130(4):460–464PubMed
4.
go back to reference Bielle F, Villa C, Giry M, Bergemer-Fouquet AM, Polivka M, Vasiljevic A, Aubriot-Lorton MH, Bernier M, Lechapt-Zalcman E, Viennet G, Sazdovitch V, Duyckaerts C, Sanson M, Figarella-Branger D, Mokhtari K, RENOP (2015) Chordoid gliomas of the third ventricle share TTF-1 expression with organum vasculosum of the lamina terminalis. Am J Surg Pathol 39(7):948–956CrossRefPubMed Bielle F, Villa C, Giry M, Bergemer-Fouquet AM, Polivka M, Vasiljevic A, Aubriot-Lorton MH, Bernier M, Lechapt-Zalcman E, Viennet G, Sazdovitch V, Duyckaerts C, Sanson M, Figarella-Branger D, Mokhtari K, RENOP (2015) Chordoid gliomas of the third ventricle share TTF-1 expression with organum vasculosum of the lamina terminalis. Am J Surg Pathol 39(7):948–956CrossRefPubMed
5.
go back to reference Desouza RM, Bodi I, Thomas N, Marsh H, Crocker M (2010) Chordoid glioma: ten years of a low-grade tumor with high morbidity. Skull Base 20(2):125–138CrossRefPubMedPubMedCentral Desouza RM, Bodi I, Thomas N, Marsh H, Crocker M (2010) Chordoid glioma: ten years of a low-grade tumor with high morbidity. Skull Base 20(2):125–138CrossRefPubMedPubMedCentral
6.
go back to reference Gallina P, Pansini G, Mouchaty H, Mura R, Buccoliero AM, Di Lorenzo N (2007) An incidentally detected third ventricle chordoid glioma. Neurol India 55(4):406–407CrossRefPubMed Gallina P, Pansini G, Mouchaty H, Mura R, Buccoliero AM, Di Lorenzo N (2007) An incidentally detected third ventricle chordoid glioma. Neurol India 55(4):406–407CrossRefPubMed
7.
go back to reference Jung TY, Jung S (2006) Third ventricular chordoid glioma with unusual aggressive behavior. Neurol Med Chir (Tokyo) 46(12):605–608CrossRef Jung TY, Jung S (2006) Third ventricular chordoid glioma with unusual aggressive behavior. Neurol Med Chir (Tokyo) 46(12):605–608CrossRef
8.
go back to reference Pomper MG, Passe TJ, Burger PC, Scheithauer BW, Brat DJ (2001) Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. Am J Neuroradiol 22(3):464–469PubMed Pomper MG, Passe TJ, Burger PC, Scheithauer BW, Brat DJ (2001) Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle. Am J Neuroradiol 22(3):464–469PubMed
9.
go back to reference Dziurzynski K, Delashaw JB, Gultekin SH, Yedinak CG, Fleseriu M (2009) Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. Endocr Pract 15(3):240–245CrossRefPubMed Dziurzynski K, Delashaw JB, Gultekin SH, Yedinak CG, Fleseriu M (2009) Diabetes insipidus, panhypopituitarism, and severe mental status deterioration in a patient with chordoid glioma: case report and literature review. Endocr Pract 15(3):240–245CrossRefPubMed
10.
11.
go back to reference Ramos-Levi AM, Duran Rodriguez-Hervada A, Mendez-Bailon M, Marco-Martinez J (2014) Drug-induced hyponatremia: an updated review. Minerva Endocrinol 39(1):1–12PubMed Ramos-Levi AM, Duran Rodriguez-Hervada A, Mendez-Bailon M, Marco-Martinez J (2014) Drug-induced hyponatremia: an updated review. Minerva Endocrinol 39(1):1–12PubMed
12.
go back to reference Grant P, Ayuk J, Bouloux PM, Cohen M, Cranston I, Murray RD, Rees A, Thatcher N, Grossman A (2015) The diagnosis and management of inpatient hyponatraemia and SIADH. Eur J Clin Invest 45(8):888–894CrossRefPubMedPubMedCentral Grant P, Ayuk J, Bouloux PM, Cohen M, Cranston I, Murray RD, Rees A, Thatcher N, Grossman A (2015) The diagnosis and management of inpatient hyponatraemia and SIADH. Eur J Clin Invest 45(8):888–894CrossRefPubMedPubMedCentral
13.
go back to reference Bourque CW (2008) Central mechanisms of osmosensation and systemic osmoregulation. Nat Rev Neurosci 9(7):519–531CrossRefPubMed Bourque CW (2008) Central mechanisms of osmosensation and systemic osmoregulation. Nat Rev Neurosci 9(7):519–531CrossRefPubMed
14.
go back to reference Glastonbury CM, Osborn AG, Salzman KL (2011) Masses and malformations of the third ventricle: normal anatomic relationships and differential diagnoses. Radiographics 31(7):1889–1905CrossRefPubMed Glastonbury CM, Osborn AG, Salzman KL (2011) Masses and malformations of the third ventricle: normal anatomic relationships and differential diagnoses. Radiographics 31(7):1889–1905CrossRefPubMed
15.
go back to reference Rees JH (2010) Chordoid glioma of the third ventricle. In: Osborn AG, Salzman KL, Barkovich AJ (eds) Diagnostic imaging: brain, 2nd edn. Lippincott Wiliams and Wilkins, Philadelphia, pp 56–57 Rees JH (2010) Chordoid glioma of the third ventricle. In: Osborn AG, Salzman KL, Barkovich AJ (eds) Diagnostic imaging: brain, 2nd edn. Lippincott Wiliams and Wilkins, Philadelphia, pp 56–57
16.
go back to reference Smith AB, Smirniotopoulos JG, Horkanyne-Szakaly I (2013) From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics 33(1):21–43CrossRefPubMed Smith AB, Smirniotopoulos JG, Horkanyne-Szakaly I (2013) From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics 33(1):21–43CrossRefPubMed
17.
go back to reference Grand S, Pasquier B, Gay E, Kremer S, Remy C, Le Bas JF (2002) Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. Neuroradiology 44:842–846CrossRefPubMed Grand S, Pasquier B, Gay E, Kremer S, Remy C, Le Bas JF (2002) Chordoid glioma of the third ventricle: CT and MRI, including perfusion data. Neuroradiology 44:842–846CrossRefPubMed
18.
go back to reference Reifenberger G, Weber T, Weber RG, Wolter M, Brandis A, Kuchelmeister K, Pilz P, Reusche E, Lichter P, Wiestler OD (1999) Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. Brain Pathol 9(4):617–626CrossRefPubMed Reifenberger G, Weber T, Weber RG, Wolter M, Brandis A, Kuchelmeister K, Pilz P, Reusche E, Lichter P, Wiestler OD (1999) Chordoid glioma of the third ventricle: immunohistochemical and molecular genetic characterization of a novel tumor entity. Brain Pathol 9(4):617–626CrossRefPubMed
19.
go back to reference Horbinski C, Dacic S, McLendon RE, Cieply K, Datto M, Brat DJ, Chu CT (2009) Chordoid glioma: a case report and molecular characterization of five cases. Brain Pathol 19(3):439–448CrossRefPubMed Horbinski C, Dacic S, McLendon RE, Cieply K, Datto M, Brat DJ, Chu CT (2009) Chordoid glioma: a case report and molecular characterization of five cases. Brain Pathol 19(3):439–448CrossRefPubMed
20.
go back to reference Ni HC, Piao YS, Lu DH, Fu YJ, Ma XL, Zhang XJ (2013) Chordoid glioma of the third ventricle: four cases including one case with papillary features. Neuropathology 33(2):134–139CrossRefPubMed Ni HC, Piao YS, Lu DH, Fu YJ, Ma XL, Zhang XJ (2013) Chordoid glioma of the third ventricle: four cases including one case with papillary features. Neuropathology 33(2):134–139CrossRefPubMed
21.
go back to reference Takei H, Bhattacharjee MB, Adesina AM (2006) Chordoid glioma of the third ventricle: report of a case with cytologic features and utility during intraoperative consultation. Acta Cytol 50(6):691–696CrossRefPubMed Takei H, Bhattacharjee MB, Adesina AM (2006) Chordoid glioma of the third ventricle: report of a case with cytologic features and utility during intraoperative consultation. Acta Cytol 50(6):691–696CrossRefPubMed
22.
go back to reference Vanhauwaert DJ, Clement F, Van Dorpe J, Deruytter MJ (2008) Chordoid glioma of the third ventricle. Acta Neurochir 150(11):1183–1191CrossRefPubMed Vanhauwaert DJ, Clement F, Van Dorpe J, Deruytter MJ (2008) Chordoid glioma of the third ventricle. Acta Neurochir 150(11):1183–1191CrossRefPubMed
23.
go back to reference Kurian KM, Summers DM, Statham PF, Smith C, Bell JE, Ironside JW (2005) Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. Neuropathol Appl Neurobiol 31:354–361CrossRefPubMed Kurian KM, Summers DM, Statham PF, Smith C, Bell JE, Ironside JW (2005) Third ventricular chordoid glioma: clinicopathological study of two cases with evidence for a poor clinical outcome despite low grade histological features. Neuropathol Appl Neurobiol 31:354–361CrossRefPubMed
24.
go back to reference Jung TY, Jung S (2006) Third ventricular chordoid glioma with unusual aggressive behavior. Neurol Med Chir 46:605–608CrossRef Jung TY, Jung S (2006) Third ventricular chordoid glioma with unusual aggressive behavior. Neurol Med Chir 46:605–608CrossRef
25.
go back to reference Raizer JJ, Shetty T, Gutin PH, Obbens EA, Holodny AI, Antonescu CR, Rosenblum MK (2003) Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. J Neurooncol 63(1):39–47CrossRefPubMed Raizer JJ, Shetty T, Gutin PH, Obbens EA, Holodny AI, Antonescu CR, Rosenblum MK (2003) Chordoid glioma: report of a case with unusual histologic features, ultrastructural study and review of the literature. J Neurooncol 63(1):39–47CrossRefPubMed
26.
go back to reference Kawasaki K, Kohno M, Inenaga C, Sato A, Hondo H, Miwa A, Fujii Y, Takahashi H (2009) Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. Neuropathology 29:85–90CrossRefPubMed Kawasaki K, Kohno M, Inenaga C, Sato A, Hondo H, Miwa A, Fujii Y, Takahashi H (2009) Chordoid glioma of the third ventricle: a report of two cases, one with ultrastructural findings. Neuropathology 29:85–90CrossRefPubMed
27.
go back to reference Kobayashi T, Tsugawa T, Hashizume C, Arita N, Hatano H, Iwami K, Nakazato Y, Mori Y (2013) Therapeutic approach to chordoid glioma of the third ventricle. Neurol Med Chir (Tokyo) 53(4):249–255CrossRef Kobayashi T, Tsugawa T, Hashizume C, Arita N, Hatano H, Iwami K, Nakazato Y, Mori Y (2013) Therapeutic approach to chordoid glioma of the third ventricle. Neurol Med Chir (Tokyo) 53(4):249–255CrossRef
Metadata
Title
Chordoid glioma of the third ventricle: a patient presenting with SIADH and a review of this rare tumor
Authors
Matilde Calanchini
Simon Cudlip
Monika Hofer
James Byrne
Andrea Fabbri
Ashley Grossman
Publication date
01-08-2016
Publisher
Springer US
Published in
Pituitary / Issue 4/2016
Print ISSN: 1386-341X
Electronic ISSN: 1573-7403
DOI
https://doi.org/10.1007/s11102-016-0711-8

Other articles of this Issue 4/2016

Pituitary 4/2016 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.