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European Journal of Nuclear Medicine and Molecular Imaging

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01-10-2006 | Editorial commentary

Cholescintigraphic measurement of liver function: how is it different from other methods?

Authors: Gerbail T. Krishnamurthy, Shakuntala Krishnamurthy

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 10/2006

Excerpt

To carry out the complex synthetic (albumin) and excretory (bilirubin) functions, the liver has a unique structure with many different types of cells (hepatocytes, Kupffer cells, stellate cells, cholangiocytes, macrophages) and architecture (endothelial space, space of Disse, canaliculi). Assessment of liver function is usually made indirectly by measurement of its products circulating in blood. Liver function is carried out through release of small protein molecules that bind to their specific receptors, which upon activation release transporter proteins that either stimulate or inhibit gene expression. Liver physiology is reviewed briefly here to emphasize the unique features of measuring cell function directly with cholescintigraphy. …

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Title: Cholescintigraphic measurement of liver function: how is it different from other methods?
Authors: Gerbail T. Krishnamurthy
Shakuntala Krishnamurthy
Publication date: 01-10-2006
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 10/2006
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-006-0182-7

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Cholescintigraphic measurement of liver function: how is it different from other methods?

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