28-04-2024 | Cholangiocarcinoma | Hepatobiliary Tumors
Is Repeat Resection for Recurrent Intrahepatic Cholangiocarcinoma Warranted?
Author:
Lavanya Yohanathan, MD
Published in:
Annals of Surgical Oncology
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Excerpt
Intrahepatic cholangiocarcinoma (ICCA) is the second most common liver cancer (following hepatocellular cancer), accounting for 5–10% of all liver cancers.
1 The incidence continues to rise in the US and worldwide and can be attributed to increased utility of cross-sectional imaging.
2‐4 Surgical resection remains the only curative intent modality for this disease. Only 10–40% of patients are considered candidates for surgical resection, and 5 year survival rates are poor (25–40%) despite R0 resection.
5‐8 This corroborates that despite optimal treatment and surgical resection with negative margins, ICCA continues to have an aggressive clinical course, natural history, and tumor biology.
9‐12 …