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Published in: Internal and Emergency Medicine 3/2021

01-04-2021 | Chloroquin | IM - COMMENTARY

Adverse drug reactions in the era of COVID-19

Author: Angela P. Cornelius

Published in: Internal and Emergency Medicine | Issue 3/2021

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Excerpt

As I read the article by Crescioli et al. [1] entitled adverse drug reactions in SARS-CoV-2 hospitalised patients: a case-series with a focus on drug-drug interactions, several thoughts came to mind. This article studied all reported COVID-19 medication adverse drug reactions in the COVID-19 units in a single center in Italy from January to May 2020. They collected data on 23 patients with reported COVID-19 treatment ADRs. These 23 patients were all Caucasian, 56% male and had a mean age over 76 years. This study showed that all patients were exposed to more than one suspected drug and 50% had more than 3 suspected medications. All but one patient had at least one drug–drug interaction. Almost 70% of patients were receiving more than 6 medications. …
Literature
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go back to reference Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, de Castilla DL, Finberg RW, Dierberg K, Tapson V, Hsieh L, Patterson TF, Paredes R, Sweeney DA, Short WR, Touloumi G, Lye DC, Ohmagari N, Oh MD, Ruiz-Palacios GM, Benfield T, Fätkenheuer G, Kortepeter MG, Atmar RL, Creech CB, Lundgren J, Babiker AG, Pett S, Neaton JD, Burgess TH, Bonnett T, Green M, Makowski M, Osinusi A, Nayak S, Lane HC, ACTT-1 Study Group Members (2020) Remdesivir for the treatment of Covid-19—final report. N Engl J Med. 383(19):1813–1826. https://doi.org/10.1056/NEJMoa2007764 (PMID: 32445440; PMCID: PMC7262788)CrossRefPubMed Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, de Castilla DL, Finberg RW, Dierberg K, Tapson V, Hsieh L, Patterson TF, Paredes R, Sweeney DA, Short WR, Touloumi G, Lye DC, Ohmagari N, Oh MD, Ruiz-Palacios GM, Benfield T, Fätkenheuer G, Kortepeter MG, Atmar RL, Creech CB, Lundgren J, Babiker AG, Pett S, Neaton JD, Burgess TH, Bonnett T, Green M, Makowski M, Osinusi A, Nayak S, Lane HC, ACTT-1 Study Group Members (2020) Remdesivir for the treatment of Covid-19—final report. N Engl J Med. 383(19):1813–1826. https://​doi.​org/​10.​1056/​NEJMoa2007764 (PMID: 32445440; PMCID: PMC7262788)CrossRefPubMed
Metadata
Title
Adverse drug reactions in the era of COVID-19
Author
Angela P. Cornelius
Publication date
01-04-2021
Publisher
Springer International Publishing
Published in
Internal and Emergency Medicine / Issue 3/2021
Print ISSN: 1828-0447
Electronic ISSN: 1970-9366
DOI
https://doi.org/10.1007/s11739-020-02603-w

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