A 10-year-old male with steroid-resistant nephrotic syndrome presented with abdominal pain, vomiting and massive ascites. An X-ray of the abdomen and chest showed air-filled dilated bowel loops in the subdiaphragmatic area with haustral markings (Fig. 1), which is the classic ‘Chilaiditi’s sign’ [1]. Hepatodiaphragmatic interposition of the colon is mostly diagnosed as an incidental finding on an erect chest or abdominal roentgenogram. Sometimes the patient may present with abdominal pain, nausea, vomiting, bloating, anorexia, diaphoresis, constipation, substernal pain, and even cardiac arrhythmias or respiratory distress [2]. When symptomatic, it is known as Chilaiditi’s syndrome. Predisposing factors include chronic constipation, shrunken liver, ascites, phrenic nerve injury and excessive aerophagia [3]. Laxity of suspensory ligaments and elevation of hemidiaphragm due to massive ascites were predisposing factors for redundancy of colon in our patient. This condition can be confused with pneumoperitoneum and subphrenic abscess radiologically. Features that point towards the diagnosis of Chilaiditi’s sign on radiography are the presence of haustra or valvulae conniventes and the fixation of the position of the radiolucency when the position of the patient is changed. In some cases computed tomography of the abdomen may be required if diagnosis is uncertain. Symptomatic patients usually improve on conservative management; however, colopexy may be required in patients with worsening of symptoms.
WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.