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European Radiology
Published in: European Radiology 4/2015

01-04-2015 | Magnetic Resonance

Characterizing the contrast of white matter and grey matter in high-resolution phase difference enhanced imaging of human brain at 3.0 T

Authors: Li Yang, Shanshan Wang, Bin Yao, Lili Li, Xiaofei Xu, Lingfei Guo, Lianxin Zhao, Xinjuan Zhang, Weibo Chen, Queenie Chan, Guangbin Wang

Published in: European Radiology | Issue 4/2015

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Abstract

Objectives

The purpose of this study was to address the feasibility of characterizing the contrast both between and within grey matter and white matter using the phase difference enhanced (PADRE) technique.

Methods

PADRE imaging was performed in 33 healthy volunteers. Vessel enhancement (VE), tissue enhancement (TE), and PADRE images were reconstructed from source images and were evaluated with regard to differentiation of grey-to-white matter interface, the stria of Gennari, and the two layers, internal sagittal stratum (ISS) and external sagittal stratum (ESS), of optic radiation.

Results

White matter regions showed decreased signal intensity compared to grey matter regions. Discrimination was sharper between white matter and cortical grey matter in TE images than in PADRE images, but was poorly displayed in VE images. The stria of Gennari was observed on all three image sets. Low-signal-intensity bands displayed in VE images representing the optic radiation were delineated as two layers of different signal intensities in TE and PADRE images. Statistically significant differences in phase shifts were found between frontal grey and white matter, as well as between ISS and ESS (p < 0.01).

Conclusions

The PADRE technique is capable of identifying grey-to-white matter interface, the stria of Gennari, and ISS and ESS, with improved contrast in PADRE and TE images compared to VE images.

Key Points

• Phase difference enhanced (PADRE) imaging can yield diverse contrasts between tissues
• The PADRE technique utilizes the inherent variety of magnetic susceptibilities
• PADRE MR imaging provides better visualization of certain cerebral anatomy in vivo
• PADRE imaging is able to delineate the stria of Gennari in the primary visual cortex
• PADRE imaging is able to identify the two optic radiation layers
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Metadata
Title
Characterizing the contrast of white matter and grey matter in high-resolution phase difference enhanced imaging of human brain at 3.0 T
Authors
Li Yang
Shanshan Wang
Bin Yao
Lili Li
Xiaofei Xu
Lingfei Guo
Lianxin Zhao
Xinjuan Zhang
Weibo Chen
Queenie Chan
Guangbin Wang
Publication date
01-04-2015
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 4/2015
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3480-7

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