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Archives of Virology
Published in: Archives of Virology 2/2019

01-02-2019 | Annotated Sequence Record

Characterization of the L genome segment of an orthohantavirus isolated from Niviventer confucianus

Authors: Xiaoxia Dai, Can Jian, Na Li, Dexin Li

Published in: Archives of Virology | Issue 2/2019

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Abstract

We sequenced and analyzed the L segment of the RNA genome of Hantaan virus (HTNV) strain NC167. This segment is 6,533 nucleotides in length and contains a single open reading frame (ORF) of 6,456 nucleotides in the antigenome sense that encodes the viral RNA-dependent RNA polymerase, which is 2,153 amino acids long with a predicted molecular mass of 246 kDa. The 5′ terminus of the viral RNA was found to contain the expected sequences that are conserved in orthohantaviruses. According to the phylogenetics and levels of sequence similarity, the L segment of HTNV NC167 is similar to but clearly distinct from the L segments of other orthohantaviruses.
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Metadata
Title
Characterization of the L genome segment of an orthohantavirus isolated from Niviventer confucianus
Authors
Xiaoxia Dai
Can Jian
Na Li
Dexin Li
Publication date
01-02-2019
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 2/2019
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-018-4074-5

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