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Published in: Documenta Ophthalmologica 2/2008

01-03-2008 | Case Report

Changes of electroretinogram without improvement of retinal circulation after radial optic neurotomy for central retinal vein occlusion

ERG changes after RON for CRVO

Authors: Eiju Sato, Shuichi Yamamoto, Kazuha Ogata, Mariko Kubota, Takeshi Sugawara, Satoshi Mizunoya

Published in: Documenta Ophthalmologica | Issue 2/2008

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Abstract

Purpose To evaluate the efficacy of radial optic neurotomy (RON) on retinal function in patients with central retinal vein occlusion (CRVO). Methods Ten eyes of 10 patients with CRVO underwent pars plana vitrectomy and RON. Standardized combined electroretinograms (ERGs) to full-field bright-flash stimuli were recorded preoperatively and, 3 months postoperatively. The best-corrected visual acuity and foveal thickness were also determined, before and 3 months postoperatively. Results The mean best-corrected visual acuity and mean foveal thickness were both significantly improved after vitrectomy and RON. The mean amplitudes of a- and b-waves did not change significantly, but the mean b/a wave ratio was increased significantly after vitrectomy and RON. An improvement of the b/a ratio was observed in six eyes, however, an improvement of retinal circulation was confirmed on postoperative fluorescein angiograms in two of these six eyes. Conclusions Significant improvements were observed in the b/a wave ratio of the standard combined ERGs after surgery in eyes with CRVO. The improvement of retinal function was most likely due to improved oxygenation of retina caused by vitrectomy and not by RON.
Literature
1.
go back to reference Opremcak EM, Bruce RA, Lomeo MD, Ridenour CD, Letson AD, Rehmar AJ (2001) Radial optic neurotomy for central retinal vein occlusion. Retina 21:408–415PubMedCrossRef Opremcak EM, Bruce RA, Lomeo MD, Ridenour CD, Letson AD, Rehmar AJ (2001) Radial optic neurotomy for central retinal vein occlusion. Retina 21:408–415PubMedCrossRef
2.
go back to reference Weizer JS, Stinnett SS, Fekrat S (2003) Radial optic neurotomy as treatment for central retinal vein occlusion. Am J Ophthalmol 136:814–819PubMedCrossRef Weizer JS, Stinnett SS, Fekrat S (2003) Radial optic neurotomy as treatment for central retinal vein occlusion. Am J Ophthalmol 136:814–819PubMedCrossRef
3.
go back to reference Garcia-Arumi J, Boixadera A, Martinez-Castillo V, Castillo R, Dou A, Corcostegui B (2003) Chorioretinal anastomosis after radial optic neurotomy for central retinal vein occlusion. Arch Ophthalmol 121:1385–1391CrossRef Garcia-Arumi J, Boixadera A, Martinez-Castillo V, Castillo R, Dou A, Corcostegui B (2003) Chorioretinal anastomosis after radial optic neurotomy for central retinal vein occlusion. Arch Ophthalmol 121:1385–1391CrossRef
4.
go back to reference Nomoto H, Shiraga F, Yamaji H, Kageyama M, Takenaka H, Baba T, Tsuchida Y (2004) Evaluation of radial optic neurotomy for central retinal vein occlusion by indocyanine green videoangiography and image analysis. Am J Ophthalmol 138:612–619PubMedCrossRef Nomoto H, Shiraga F, Yamaji H, Kageyama M, Takenaka H, Baba T, Tsuchida Y (2004) Evaluation of radial optic neurotomy for central retinal vein occlusion by indocyanine green videoangiography and image analysis. Am J Ophthalmol 138:612–619PubMedCrossRef
5.
go back to reference Karpe G, Uchermann A (1955) The clinical electroretinogram VII The electroretinogram in circulatory disturbances of the retina. Acta Ophthalmol 33:493–516 Karpe G, Uchermann A (1955) The clinical electroretinogram VII The electroretinogram in circulatory disturbances of the retina. Acta Ophthalmol 33:493–516
6.
go back to reference Karpe G, Germanis M (1962) The prognostic value of the electroretinogram in thrombosis of the retinal veins. Acta Ophthalmol Suppl 70:202–229PubMedCrossRef Karpe G, Germanis M (1962) The prognostic value of the electroretinogram in thrombosis of the retinal veins. Acta Ophthalmol Suppl 70:202–229PubMedCrossRef
7.
go back to reference Sabates R, Hirose T, McMeel JW (1983) Electroretinography in the prognosis and classification of central retinal vein occlusion. Arch Ophthalmol 101:232–235PubMed Sabates R, Hirose T, McMeel JW (1983) Electroretinography in the prognosis and classification of central retinal vein occlusion. Arch Ophthalmol 101:232–235PubMed
8.
go back to reference Hayreh SS, Klugman MR, Podhajsky P, Kolder HE (1989) Electroretinography in central retinal vein occlusion. Correlation of electroretinographic changes with pupillary abnormalities. Graefes Arch Clin Exp Ophthalmol 227:549–561PubMedCrossRef Hayreh SS, Klugman MR, Podhajsky P, Kolder HE (1989) Electroretinography in central retinal vein occlusion. Correlation of electroretinographic changes with pupillary abnormalities. Graefes Arch Clin Exp Ophthalmol 227:549–561PubMedCrossRef
9.
go back to reference Central Vein Occlusion Study Group (1995) A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion. Ophthalmology 102:1434–1444 Central Vein Occlusion Study Group (1995) A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion. Ophthalmology 102:1434–1444
10.
go back to reference Shinoda K, Ohde H, Mashima Y, Inoue R, Ishida S, Inoue M, Kawashima S, Oguchi Y (2001) On- and off-responses of the photopic electroretinograms in X-linked juvenile retinoschisis. Am J Ophthalmol 131:489–494PubMedCrossRef Shinoda K, Ohde H, Mashima Y, Inoue R, Ishida S, Inoue M, Kawashima S, Oguchi Y (2001) On- and off-responses of the photopic electroretinograms in X-linked juvenile retinoschisis. Am J Ophthalmol 131:489–494PubMedCrossRef
11.
go back to reference Marmor MF, Holder GE, Seeliger MW, Yamamoto S (2004) International Society for Clinical Electrophysiology of Vision Standard for clinical electroretinography (2004 update). Doc Ophthalmol 108:107–114PubMedCrossRef Marmor MF, Holder GE, Seeliger MW, Yamamoto S (2004) International Society for Clinical Electrophysiology of Vision Standard for clinical electroretinography (2004 update). Doc Ophthalmol 108:107–114PubMedCrossRef
12.
go back to reference Hayreh SS (2004) Radial optic neurotomy for nonischemic central retinal vein occlusion. Arch Ophthalmol 122:1572–1573PubMedCrossRef Hayreh SS (2004) Radial optic neurotomy for nonischemic central retinal vein occlusion. Arch Ophthalmol 122:1572–1573PubMedCrossRef
13.
go back to reference Vogel A, Holz FG, Loeffler KU (2006) Histopathologic findings after radial optic neurotomy in central retinal vein occlusion. Am J Ophthalmol 141:203–205PubMedCrossRef Vogel A, Holz FG, Loeffler KU (2006) Histopathologic findings after radial optic neurotomy in central retinal vein occlusion. Am J Ophthalmol 141:203–205PubMedCrossRef
14.
go back to reference Horio N, Horiguchi M (2005) Central retinal vein occlusion with further reduction of retinal blood flow one year after radial optic neurotomy. Am J Ophthalmol 139:926–927PubMedCrossRef Horio N, Horiguchi M (2005) Central retinal vein occlusion with further reduction of retinal blood flow one year after radial optic neurotomy. Am J Ophthalmol 139:926–927PubMedCrossRef
15.
go back to reference Yamamoto S, Saito W, Yagi F, Takeuchi S, Sato E, Mizunoya S (2004) Vitrectomy with or without arteriovenous adventitial sheathotomy for macular edema associated with branch retinal vein occlusion. Am J Ophthalmol 138:907–914PubMedCrossRef Yamamoto S, Saito W, Yagi F, Takeuchi S, Sato E, Mizunoya S (2004) Vitrectomy with or without arteriovenous adventitial sheathotomy for macular edema associated with branch retinal vein occlusion. Am J Ophthalmol 138:907–914PubMedCrossRef
16.
go back to reference Yamamoto T, Akabane N, Takeuchi S (2001) Vitrectomy for diabetic macular edema: the role of posterior vitreous detachment and epimacular membrane. Am J Ophthalmol 132:369–377PubMedCrossRef Yamamoto T, Akabane N, Takeuchi S (2001) Vitrectomy for diabetic macular edema: the role of posterior vitreous detachment and epimacular membrane. Am J Ophthalmol 132:369–377PubMedCrossRef
17.
go back to reference Stefansson E, Novack RL, Hatchell DL (1990) Vitrectomy prevents retinal hypoxia in branch retinal vein occlusion. Invest Ophthalmol Vis Sci 31:284–289PubMed Stefansson E, Novack RL, Hatchell DL (1990) Vitrectomy prevents retinal hypoxia in branch retinal vein occlusion. Invest Ophthalmol Vis Sci 31:284–289PubMed
18.
go back to reference Mandelcorn MS, Nrusimhadevara RK (2004) Internal limiting membrane peeling for decompression of macular edema in retinal vein occlusion: a report of 14 cases. Retina 24:348–355PubMedCrossRef Mandelcorn MS, Nrusimhadevara RK (2004) Internal limiting membrane peeling for decompression of macular edema in retinal vein occlusion: a report of 14 cases. Retina 24:348–355PubMedCrossRef
19.
go back to reference Radetzky S, Walter P, Fauser S, Koizumi K, Kirchhof B, Joussen AM (2004) Visual outcome of patients with macular edema after pars plana vitrectomy and indocyanine green-assisted peeling of the internal limiting membrane. Graefes Arch Clin Exp Ophthalmol 242:273–278PubMedCrossRef Radetzky S, Walter P, Fauser S, Koizumi K, Kirchhof B, Joussen AM (2004) Visual outcome of patients with macular edema after pars plana vitrectomy and indocyanine green-assisted peeling of the internal limiting membrane. Graefes Arch Clin Exp Ophthalmol 242:273–278PubMedCrossRef
20.
go back to reference Matsui Y, Katsumi O, Sakaue H, Hirose T (1994) Electroretinogram b/a wave ratio improvement in central retinal vein obstruction. Br J Ophthalmol 78:191–198PubMedCrossRef Matsui Y, Katsumi O, Sakaue H, Hirose T (1994) Electroretinogram b/a wave ratio improvement in central retinal vein obstruction. Br J Ophthalmol 78:191–198PubMedCrossRef
21.
go back to reference Yamamoto S, Takatsuna Y, Sato E, Mizunoya S (2005) Central retinal artery occlusion after radial optic neurotomy in a patient with central retinal vein occlusion. Am J Ophthalmol 139:206–207PubMedCrossRef Yamamoto S, Takatsuna Y, Sato E, Mizunoya S (2005) Central retinal artery occlusion after radial optic neurotomy in a patient with central retinal vein occlusion. Am J Ophthalmol 139:206–207PubMedCrossRef
22.
go back to reference Schneider U, Inhoffen W, Grisanti S, Bartz-Schmidt KU (2005) Characteristics of visual field defects by scanning laser ophthalmoscope microperimetry after radial optic neurotomy for central retinal vein occlusion. Retina 25:704–712PubMedCrossRef Schneider U, Inhoffen W, Grisanti S, Bartz-Schmidt KU (2005) Characteristics of visual field defects by scanning laser ophthalmoscope microperimetry after radial optic neurotomy for central retinal vein occlusion. Retina 25:704–712PubMedCrossRef
23.
go back to reference Takaya K, Suzuki Y, Nakazawa M (2006) Massive hemorrhagic retinal detachment during radial optic neurotomy. Graefes Arch Clin Exp Ophthalmol 244:265–267PubMedCrossRef Takaya K, Suzuki Y, Nakazawa M (2006) Massive hemorrhagic retinal detachment during radial optic neurotomy. Graefes Arch Clin Exp Ophthalmol 244:265–267PubMedCrossRef
Metadata
Title
Changes of electroretinogram without improvement of retinal circulation after radial optic neurotomy for central retinal vein occlusion
ERG changes after RON for CRVO
Authors
Eiju Sato
Shuichi Yamamoto
Kazuha Ogata
Mariko Kubota
Takeshi Sugawara
Satoshi Mizunoya
Publication date
01-03-2008
Publisher
Springer-Verlag
Published in
Documenta Ophthalmologica / Issue 2/2008
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI
https://doi.org/10.1007/s10633-007-9103-8

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