Skip to main content
Top
Published in: Documenta Ophthalmologica 2/2008

01-03-2008 | Editorial

Imaging and the perspective of clinical electrophysiology

Author: Ulrich Kellner

Published in: Documenta Ophthalmologica | Issue 2/2008

Login to get access

Excerpt

Clinical electrophysiology allows a detailed analysis of retinal function in various disorders. When for decades the morphological examination of the retina was limited to ophthalmoscopy and fluorescein angiography, electrophysiological techniques allowed detection of retinal abnormalities in morphologically “normal” retina: e.g. cone dystrophies with the full-field ERG, early stages of macular dystrophies with the pattern ERG (PERG) or multifocal ERG (mfERG), early stages of chloroquine retinopathy with the mfERG, non-manifesting carriers of Best disease with the EOG or retinal ganglion cell damage in autosomal dominant optic atrophy with the VEP. …
Literature
2.
go back to reference Catier A, Tadayoni R, Paques M, Erginay A, Haouchine B, Gaudric A, Massin P (2005) Characterization of macular edema from various etiologies by optical coherence tomography. Am J Ophthalmol 140:200–206PubMed Catier A, Tadayoni R, Paques M, Erginay A, Haouchine B, Gaudric A, Massin P (2005) Characterization of macular edema from various etiologies by optical coherence tomography. Am J Ophthalmol 140:200–206PubMed
3.
go back to reference Delori FC, Dorey CK, Staurenghi G, Arend O, Goger DG, Weiter JJ (1995) In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 36:718–729PubMed Delori FC, Dorey CK, Staurenghi G, Arend O, Goger DG, Weiter JJ (1995) In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 36:718–729PubMed
4.
go back to reference Keilhauer CN, Delori FC (2006) Near-infrared autofluorescence imaging of the fundus: visualization of ocular melanin. Invest Ophthalmol Vis Sci 47:3556–3564PubMedCrossRef Keilhauer CN, Delori FC (2006) Near-infrared autofluorescence imaging of the fundus: visualization of ocular melanin. Invest Ophthalmol Vis Sci 47:3556–3564PubMedCrossRef
5.
go back to reference Wabbels B, Demmler A, Paunescu K, Wegscheider E, Preising MN, Lorenz B (2006) Fundus autofluorescence in children and teenagers with hereditary retinal diseases. Graefes Arch Clin Exp Ophthalmol 244:36–45PubMedCrossRef Wabbels B, Demmler A, Paunescu K, Wegscheider E, Preising MN, Lorenz B (2006) Fundus autofluorescence in children and teenagers with hereditary retinal diseases. Graefes Arch Clin Exp Ophthalmol 244:36–45PubMedCrossRef
6.
go back to reference Weinberger AW, Lappas A, Kirschkamp T, Mazinani BA, Huth JK, Mohammadi B, Walter P (2006) Fundus near infrared fluorescence correlates with fundus near infrared reflectance. Invest Ophthalmol Vis Sci 47:3098–3108PubMedCrossRef Weinberger AW, Lappas A, Kirschkamp T, Mazinani BA, Huth JK, Mohammadi B, Walter P (2006) Fundus near infrared fluorescence correlates with fundus near infrared reflectance. Invest Ophthalmol Vis Sci 47:3098–3108PubMedCrossRef
7.
go back to reference Lubinski W, Goslawski W, Penkala K, Drobek-Slowik M, Karczewicz D (2007) A 43-year-old man with reduced visual acuity and normal fundus: occult macular dystrophy-case report. Doc Ophthalmol. doi:10.1007/s10633-007-9086-5 PubMed Lubinski W, Goslawski W, Penkala K, Drobek-Slowik M, Karczewicz D (2007) A 43-year-old man with reduced visual acuity and normal fundus: occult macular dystrophy-case report. Doc Ophthalmol. doi:10.​1007/​s10633-007-9086-5 PubMed
9.
go back to reference Renner AB, Kellner U, Fiebig B, Cropp E, Foerster MH, Weber BH (2007) ERG variability in X-linked congenital retinoschisis patients with mutations in the RS1 gene and the diagnostic importance of fundus autofluorescence and OCT. Doc Ophthalmol. doi:10.1007/s10633-007-9094-5 PubMed Renner AB, Kellner U, Fiebig B, Cropp E, Foerster MH, Weber BH (2007) ERG variability in X-linked congenital retinoschisis patients with mutations in the RS1 gene and the diagnostic importance of fundus autofluorescence and OCT. Doc Ophthalmol. doi:10.​1007/​s10633-007-9094-5 PubMed
10.
go back to reference Wabbels B, Preising MN, Kretschmann U, Demmler A, Lorenz B (2006) Genotype-phenotype correlation and longitudinal course in ten families with Best vitelliform macular dystrophy. Graefes Arch Clin Exp Ophthalmol 244:1453–1466CrossRef Wabbels B, Preising MN, Kretschmann U, Demmler A, Lorenz B (2006) Genotype-phenotype correlation and longitudinal course in ten families with Best vitelliform macular dystrophy. Graefes Arch Clin Exp Ophthalmol 244:1453–1466CrossRef
11.
go back to reference Altintas O, Iseri P, Ozkan B, Caglar Y (2007) Correlation between retinal morphological and functional findings and clinical severity in Parkinson’s disease. Doc Ophthalmol. doi:10.1007/s10633-007-9091-8 PubMed Altintas O, Iseri P, Ozkan B, Caglar Y (2007) Correlation between retinal morphological and functional findings and clinical severity in Parkinson’s disease. Doc Ophthalmol. doi:10.​1007/​s10633-007-9091-8 PubMed
12.
go back to reference Jacobson SG, Cideciyan AV, Aleman TS, Pianta MJ, Sumaroka A, Schwartz SB, Smilko EE, Milam AH, Sheffield VC, Stone EM (2003) Crumbs homolog 1 (CRB1) mutations result in a thick human retina with abnormal lamination. Hum Mol Genet 12:1073–1078PubMedCrossRef Jacobson SG, Cideciyan AV, Aleman TS, Pianta MJ, Sumaroka A, Schwartz SB, Smilko EE, Milam AH, Sheffield VC, Stone EM (2003) Crumbs homolog 1 (CRB1) mutations result in a thick human retina with abnormal lamination. Hum Mol Genet 12:1073–1078PubMedCrossRef
13.
go back to reference Lorenz B, Wabbels B, Wegscheider E, Hamel CP, Drexler W, Preising MN (2004) Lack of fundus autofluorescence to 488 nanometers from childhood on in patients with early-onset severe retinal dystrophy associated with mutations in RPE65. Ophthalmology 111:1585–1594PubMedCrossRef Lorenz B, Wabbels B, Wegscheider E, Hamel CP, Drexler W, Preising MN (2004) Lack of fundus autofluorescence to 488 nanometers from childhood on in patients with early-onset severe retinal dystrophy associated with mutations in RPE65. Ophthalmology 111:1585–1594PubMedCrossRef
14.
go back to reference Robson AG, Michaelides M, Saihan Z, Bird AC, Webster AR, Moore AT, Fitzke FW, Holder GE (2007) Functional characteristics of patients with retinal dystrophy that manifest abnormal parafoveal annuli of high density fundus autofluorescence; a review and update. Doc Ophthalmol. doi:10.1007/s10633-007-9087-4 PubMed Robson AG, Michaelides M, Saihan Z, Bird AC, Webster AR, Moore AT, Fitzke FW, Holder GE (2007) Functional characteristics of patients with retinal dystrophy that manifest abnormal parafoveal annuli of high density fundus autofluorescence; a review and update. Doc Ophthalmol. doi:10.​1007/​s10633-007-9087-4 PubMed
15.
go back to reference Kellner U, Kellner S, Weinitz S (2008) Chloroquine retinopathy: lipofuscin- and melanin-related fundus autofluorescence, optical coherence tomography and multifocal electroretinography. Doc Ophthalmol. doi:10.1007/s10633-007-9105-6 Kellner U, Kellner S, Weinitz S (2008) Chloroquine retinopathy: lipofuscin- and melanin-related fundus autofluorescence, optical coherence tomography and multifocal electroretinography. Doc Ophthalmol. doi:10.​1007/​s10633-007-9105-6
16.
go back to reference Shetty R, Pai SA, Vincent A, Shetty N, Narayana KM, Sinha B, Shetty BK (2007) Electrophysiological and structural assessment of the central retina following intravitreal injection of bevacizumab for treatment of macular edema. Doc Ophthalmol. doi:10.1007/s10633-007-9090-9 PubMed Shetty R, Pai SA, Vincent A, Shetty N, Narayana KM, Sinha B, Shetty BK (2007) Electrophysiological and structural assessment of the central retina following intravitreal injection of bevacizumab for treatment of macular edema. Doc Ophthalmol. doi:10.​1007/​s10633-007-9090-9 PubMed
Metadata
Title
Imaging and the perspective of clinical electrophysiology
Author
Ulrich Kellner
Publication date
01-03-2008
Publisher
Springer-Verlag
Published in
Documenta Ophthalmologica / Issue 2/2008
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI
https://doi.org/10.1007/s10633-007-9106-5

Other articles of this Issue 2/2008

Documenta Ophthalmologica 2/2008 Go to the issue