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Journal of Gastrointestinal Surgery

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01-01-2010 | Original Article

Changes in Quality-of-Life Following Laparoscopic Cholecystectomy in Adult Patients with Cholelithiasis

Authors: Hen-Hui Lien, Chi-Cheng Huang, Pa-Chun Wang, Ching-Shui Huang, Ya-Hui Chen, Tzung-Li Lin, Meng-Chao Tsai

Published in: Journal of Gastrointestinal Surgery | Issue 1/2010

Abstract

Background

The aim of this study was to evaluate changes in quality-of-life following laparoscopic cholecystectomy (LC) in adults with cholelithiasis.

Methods

Patients were evaluated with the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the Gastrointestinal Quality of Life Index (GIQLI) preoperatively and 12 months after LC. Outcome predictors were analyzed using correlation and regression statistics.

Results

Ninety-nine patients were enrolled (male/female, 32:67, age 49.8 ± 13.7 years old). At baseline, patients performed inferiorly to general population in all SF-36 general health dimensions (p < 0.0001). Postoperatively, the “role-physical”, “role-emotional”, and “bodily pain” dimensions of health significantly improved. There were significant improvements in GIQLI “total”, “physical well-being”, “mental well-being”, “gastrointestinal digestion”, and “defecation” subscales scores. Serum direct bilirubin level and drainage tube indwelling were significant predictors for quality-of-life improvement following LC.

Conclusions

LC can greatly reduce gastrointestinal symptoms to improve quality-of-life for patients with cholelithiasis. Patients with severe baseline conditions may benefit from greater quality-of-life improvement following LC.

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Title: Changes in Quality-of-Life Following Laparoscopic Cholecystectomy in Adult Patients with Cholelithiasis
Authors: Hen-Hui Lien
Chi-Cheng Huang
Pa-Chun Wang
Ching-Shui Huang
Ya-Hui Chen
Tzung-Li Lin
Meng-Chao Tsai
Publication date: 01-01-2010
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 1/2010
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-009-1062-9

At a glance: The STEP trials

Springer Medicine

Changes in Quality-of-Life Following Laparoscopic Cholecystectomy in Adult Patients with Cholelithiasis

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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