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01-05-2011 | Clinical Research

Change in Predicted 10-Year Cardiovascular Risk Following Roux-en-Y Gastric Bypass Surgery: Who Benefits?

Authors: Simara P. Donadelli, Wilson Salgado Jr., Julio S. Marchini, Andre Schmidt, Cristiana A. F. Amato, Reginaldo Ceneviva, Jose Ernesto Dos Santos, Carla Barbosa Nonino

Published in: Obesity Surgery | Issue 5/2011

Abstract

Background

The risk of developing cardiovascular disease is higher in obese than in non-obese individuals. Surgery for obesity is effective in reducing weight and resolution of diabetes, hypertension, and dyslipidemia. Our aim was to assess the estimated 10-year cardiovascular risk of obese patients before and after treatment of obesity with a gastric bypass.

Methods

Weight, body mass index systolic and diastolic blood pressure, lipid profile, glycemia, and history of cardiovascular disease were obtained for obese patients before and 2 years after Roux-en-Y gastric bypass surgery. Ten-year cardiovascular risk was calculated using the Framingham score.

Results

Forty-two patients were included in the study. We observed a significant reduction (p < 0.05) of 10-year cardiovascular risk mainly associated with weight reduction and improvement of comorbidities associated with obesity. The benefits were greater among patients who already presented known risk factors such as diabetes and hypertension. Superobese patients benefited as early as 2 years after surgery, when weight loss was greater.

Conclusions

Weight loss secondary to surgery was sustained after 2 years and promoted improvement of comorbidities, with an important reduction of 10-year cardiovascular risk especially among patients with previous risk factors.

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Title: Change in Predicted 10-Year Cardiovascular Risk Following Roux-en-Y Gastric Bypass Surgery: Who Benefits?
Authors: Simara P. Donadelli
Wilson Salgado Jr.
Julio S. Marchini
Andre Schmidt
Cristiana A. F. Amato
Reginaldo Ceneviva
Jose Ernesto Dos Santos
Carla Barbosa Nonino
Publication date: 01-05-2011
Publisher: Springer-Verlag
Published in: Obesity Surgery / Issue 5/2011
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-010-0348-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Change in Predicted 10-Year Cardiovascular Risk Following Roux-en-Y Gastric Bypass Surgery: Who Benefits?

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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