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Obesity Surgery
Published in: Obesity Surgery 5/2011

01-05-2011 | Case Report

Reduced Phenytoin Levels in an Epileptic Patient following Roux-En-Y Gastric Bypass for Obesity

Authors: Dimitrios J. Pournaras, David Footitt, David Mahon, Richard Welbourn

Published in: Obesity Surgery | Issue 5/2011

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Abstract

Despite widespread uptake of bariatric procedures for severe obesity, changes in pharmacodynamics after surgery are poorly understood. We report an epileptic patient who had a seizure following gastric bypass, although he had been asymptomatic for 30 years and without any change in his treatment. Phenytoin levels were undetectable despite a high dose. Drugs with a narrow therapeutic range such as phenytoin should be prescribed with caution after bariatric surgery.
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Metadata
Title
Reduced Phenytoin Levels in an Epileptic Patient following Roux-En-Y Gastric Bypass for Obesity
Authors
Dimitrios J. Pournaras
David Footitt
David Mahon
Richard Welbourn
Publication date
01-05-2011
Publisher
Springer-Verlag
Published in
Obesity Surgery / Issue 5/2011
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-010-0107-1

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