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Published in: World Journal of Surgical Oncology 1/2013

Open Access 01-12-2013 | Case report

Cerebral iodized lipid embolization via a pulmonary arteriovenous shunt: rare complication of transcatheter arterial embolization for hepatocellular carcinoma

Authors: Zoltán Bánsághi, Pál Novák Kaposi, Gábor Lovas, Gyöngyvér Szentmártoni, György Várallyay, Pál Bata, Ildikó Kalina, Balázs Futácsi, Viktor Bérczi

Published in: World Journal of Surgical Oncology | Issue 1/2013

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Abstract

We report the first European case of cerebral iodized lipid embolism post transcatheter arterial embolization for hepatocellular carcinoma. Lipiodol emboli and corresponding multifocal brain ischemia were documented with computed tomography (CT) and magnetic resonance (MR) in the acutely symptomatic patient. Transcranial Doppler sonography with contrast indicated a right-to-left shunt, while on a follow-up CT scan lipiodol embolization was detected in both lungs. Dilated pulmonary vessels and thick vascular channels were seen in the vicinity of the right diaphragm suggestive of pulmonary arteriovenous shunt. The patient symptoms regressed with supportive care alone, but he died 5 months later due to hepatic failure unrelated to the procedure.
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Literature
1.
go back to reference Thorgeirsson SS, Grisham JW: Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet. 2002, 31: 339-346.CrossRefPubMed Thorgeirsson SS, Grisham JW: Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet. 2002, 31: 339-346.CrossRefPubMed
2.
4.
go back to reference Matsumoto K, Nojiri J, Takase Y, Egashira Y, Azama S, Kato A, Kitahara K, Miyazaki K, Kudo S: Cerebral lipiodol embolism: a complication of transcatheter arterial chemoembolization for hepatocellular carcinoma. Cardiovasc Intervent Radiol. 2007, 30: 512-514.CrossRefPubMed Matsumoto K, Nojiri J, Takase Y, Egashira Y, Azama S, Kato A, Kitahara K, Miyazaki K, Kudo S: Cerebral lipiodol embolism: a complication of transcatheter arterial chemoembolization for hepatocellular carcinoma. Cardiovasc Intervent Radiol. 2007, 30: 512-514.CrossRefPubMed
5.
go back to reference Gossage JR, Kanj G: Pulmonary arteriovenous malformations. A state of the art review. Am J Respir Crit Care Med. 1998, 158: 643-661.CrossRefPubMed Gossage JR, Kanj G: Pulmonary arteriovenous malformations. A state of the art review. Am J Respir Crit Care Med. 1998, 158: 643-661.CrossRefPubMed
6.
go back to reference McAdams HP, Erasmus J, Crockett R, Mitchell J, Godwin JD, McDermott VG: The hepatopulmonary syndrome: radiologic findings in 10 patients. AJR Am J Roentgenol. 1996, 166: 1379-1385.CrossRefPubMed McAdams HP, Erasmus J, Crockett R, Mitchell J, Godwin JD, McDermott VG: The hepatopulmonary syndrome: radiologic findings in 10 patients. AJR Am J Roentgenol. 1996, 166: 1379-1385.CrossRefPubMed
7.
go back to reference Wu L, Yang YF, Liang J, Shen SQ, Ge NJ, Wu MC: Cerebral lipiodol embolism following transcatheter arterial chemoembolization for hepatocellular carcinoma. World J Gastroenterol. 2010, 16: 398-402.PubMedCentralCrossRefPubMed Wu L, Yang YF, Liang J, Shen SQ, Ge NJ, Wu MC: Cerebral lipiodol embolism following transcatheter arterial chemoembolization for hepatocellular carcinoma. World J Gastroenterol. 2010, 16: 398-402.PubMedCentralCrossRefPubMed
8.
go back to reference Zach V, Rapaport B, Yoo JY, Goldfeder L, Weinberger J: Multiple ischemic strokes after transcatheter arterial chemoembolization for hepatocellular carcinoma with a radiographic and pathological correlate. J Stroke Cerebrovasc Dis. 2012, 21: 217-224.CrossRefPubMed Zach V, Rapaport B, Yoo JY, Goldfeder L, Weinberger J: Multiple ischemic strokes after transcatheter arterial chemoembolization for hepatocellular carcinoma with a radiographic and pathological correlate. J Stroke Cerebrovasc Dis. 2012, 21: 217-224.CrossRefPubMed
9.
go back to reference Yoo KM, Yoo BG, Kim KS, Lee SU, Han BH: Cerebral lipiodol embolism during transcatheter arterial chemoembolization. Neurology. 2004, 63: 181-183.CrossRefPubMed Yoo KM, Yoo BG, Kim KS, Lee SU, Han BH: Cerebral lipiodol embolism during transcatheter arterial chemoembolization. Neurology. 2004, 63: 181-183.CrossRefPubMed
10.
Metadata
Title
Cerebral iodized lipid embolization via a pulmonary arteriovenous shunt: rare complication of transcatheter arterial embolization for hepatocellular carcinoma
Authors
Zoltán Bánsághi
Pál Novák Kaposi
Gábor Lovas
Gyöngyvér Szentmártoni
György Várallyay
Pál Bata
Ildikó Kalina
Balázs Futácsi
Viktor Bérczi
Publication date
01-12-2013
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2013
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-11-122

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