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Published in: Acta Neurochirurgica 3/2022

01-03-2022 | Central Nervous System Trauma | Review Article - Brain trauma

Long-term outcome after severe traumatic brain injury: a systematic literature review

Authors: Cassidy Q. B. Mostert, Ranjit D. Singh, Maxime Gerritsen, Erwin J. O. Kompanje, Gerard M. Ribbers, Wilco C. Peul, Jeroen T. J. M. van Dijck

Published in: Acta Neurochirurgica | Issue 3/2022

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Abstract

Background

Expectation of long-term outcome is an important factor in treatment decision-making after severe traumatic brain injury (sTBI). Conclusive long-term outcome data substantiating these decisions is nowadays lacking. This systematic review aimed to provide an overview of the scientific literature on long-term outcome after sTBI.

Methods

A systematic search was conducted using PubMed from 2008 to 2020. Studies were included when reporting long-term outcome ≥ 2 years after sTBI (GCS 3–8 or AIS head score ≥ 4), using standardized outcome measures. Study quality and risk of bias were assessed using the QUIPS tool.

Results

Twenty observational studies were included. Studies showed substantial variation in study objectives and study methodology. GOS-E (n = 12) and GOS (n = 8) were the most frequently used outcome measures. Mortality was reported in 46% of patients (range 18–75%). Unfavourable outcome rates ranged from 29 to 100% and full recovery was seen in 21–27% of patients. Most surviving patients reported SF-36 scores lower than the general population.

Conclusion

Literature on long-term outcome after sTBI was limited and heterogeneous. Mortality and unfavourable outcome rates were high and persisting sequelae on multiple domains common. Nonetheless, a considerable proportion of survivors achieved favourable outcome. Future studies should incorporate standardized multidimensional and temporal long-term outcome measures to strengthen the evidence-base for acute and subacute decision-making.

Highlights

1. Expectation of long-term outcome is an important factor in treatment decision-making for patients with severe traumatic brain injury (sTBI).
2. Favourable outcome and full recovery after sTBI are possible, but mortality and unfavourable outcome rates are high.
3. sTBI survivors are likely to suffer from a wide range of long-term consequences, underscoring the need for long-term and multi-modality outcome assessment in future studies.
4. The quality of the scientific literature on long-term outcome after sTBI can and should be improved to advance treatment decision-making.
Appendix
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Literature
1.
go back to reference Ahmadi SA, Meier U, Lemcke J (2010) Detailed long-term outcome analysis after decompressive craniectomy for severe traumatic brain injury. Brain Inj 24(13–14):1539–1549PubMedCrossRef Ahmadi SA, Meier U, Lemcke J (2010) Detailed long-term outcome analysis after decompressive craniectomy for severe traumatic brain injury. Brain Inj 24(13–14):1539–1549PubMedCrossRef
2.
go back to reference Andersson E, Rackauskaite D, Svanborg E, Csajbok L, Ost M, Nellgard B (2017) A prospective outcome study observing patients with severe traumatic brain injury over 10–15 years. Acta Anaesthesiol Scand 61(5):502–512PubMedCrossRef Andersson E, Rackauskaite D, Svanborg E, Csajbok L, Ost M, Nellgard B (2017) A prospective outcome study observing patients with severe traumatic brain injury over 10–15 years. Acta Anaesthesiol Scand 61(5):502–512PubMedCrossRef
3.
go back to reference Andruszkow H, Urner J, Deniz E, Probst C, Grun O, Lohse R et al (2013) Subjective impact of traumatic brain injury on long-term outcome at a minimum of 10 years after trauma-first results of a survey on 368 patients from a single academic trauma center in Germany. Patient Saf Surg 7(1):32PubMedPubMedCentralCrossRef Andruszkow H, Urner J, Deniz E, Probst C, Grun O, Lohse R et al (2013) Subjective impact of traumatic brain injury on long-term outcome at a minimum of 10 years after trauma-first results of a survey on 368 patients from a single academic trauma center in Germany. Patient Saf Surg 7(1):32PubMedPubMedCentralCrossRef
4.
go back to reference Azouvi P, Ghout I, Bayen E, Darnoux E, Azerad S, Ruet A et al (2016) Disability and health-related quality-of-life 4 years after a severe traumatic brain injury: a structural equation modelling analysis. Brain Inj 30(13–14):1665–1671PubMedCrossRef Azouvi P, Ghout I, Bayen E, Darnoux E, Azerad S, Ruet A et al (2016) Disability and health-related quality-of-life 4 years after a severe traumatic brain injury: a structural equation modelling analysis. Brain Inj 30(13–14):1665–1671PubMedCrossRef
5.
go back to reference Badjatia N, Carney N, Crocco TJ, Fallat ME, Hennes HM, Jagoda AS et al (2008) Guidelines for prehospital management of traumatic brain injury 2nd edition. Prehosp Emerg Care 12(Suppl 1):S1-52PubMedCrossRef Badjatia N, Carney N, Crocco TJ, Fallat ME, Hennes HM, Jagoda AS et al (2008) Guidelines for prehospital management of traumatic brain injury 2nd edition. Prehosp Emerg Care 12(Suppl 1):S1-52PubMedCrossRef
6.
go back to reference Baguley IJ, Nott MT, Howle AA, Simpson GK, Browne S, King AC et al (2012) Late mortality after severe traumatic brain injury in New South Wales: a multicentre study. Med J Aust 196(1):40–45PubMedCrossRef Baguley IJ, Nott MT, Howle AA, Simpson GK, Browne S, King AC et al (2012) Late mortality after severe traumatic brain injury in New South Wales: a multicentre study. Med J Aust 196(1):40–45PubMedCrossRef
7.
go back to reference Bayen E, Jourdan C, Ghout I, Pradat-Diehl P, Darnoux E, Nelson G et al (2018) Negative impact of litigation procedures on patient outcomes four years after severe traumatic brain injury: results from the PariS-traumatic brain injury study. Disabil Rehabil 40(17):2040–2047PubMedCrossRef Bayen E, Jourdan C, Ghout I, Pradat-Diehl P, Darnoux E, Nelson G et al (2018) Negative impact of litigation procedures on patient outcomes four years after severe traumatic brain injury: results from the PariS-traumatic brain injury study. Disabil Rehabil 40(17):2040–2047PubMedCrossRef
8.
go back to reference Bivona U, Riccio A, Ciurli P, Carlesimo GA, Delle Donne V, Pizzonia E et al (2014) Low self-awareness of individuals with severe traumatic brain injury can lead to reduced ability to take another person’s perspective. J Head Trauma Rehabil 29(2):157–171PubMedCrossRef Bivona U, Riccio A, Ciurli P, Carlesimo GA, Delle Donne V, Pizzonia E et al (2014) Low self-awareness of individuals with severe traumatic brain injury can lead to reduced ability to take another person’s perspective. J Head Trauma Rehabil 29(2):157–171PubMedCrossRef
9.
go back to reference Bjelland I, Dahl AA, Haug TT, Neckelmann D (2002) The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res 52(2):69–77PubMedCrossRef Bjelland I, Dahl AA, Haug TT, Neckelmann D (2002) The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res 52(2):69–77PubMedCrossRef
10.
go back to reference Bramlett HM, Dietrich WD (2015) Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes. J Neurotrauma 32(23):1834–1848PubMedPubMedCentralCrossRef Bramlett HM, Dietrich WD (2015) Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes. J Neurotrauma 32(23):1834–1848PubMedPubMedCentralCrossRef
11.
go back to reference Bullock R, Chesnut RM, Clifton G, Ghajar J, Marion DW, Narayan RK et al (1996) Guidelines for the management of severe head injury. Brain Trauma Foundation. Eur J Emerg Med 3(2):109–27PubMedCrossRef Bullock R, Chesnut RM, Clifton G, Ghajar J, Marion DW, Narayan RK et al (1996) Guidelines for the management of severe head injury. Brain Trauma Foundation. Eur J Emerg Med 3(2):109–27PubMedCrossRef
12.
go back to reference Carney N, Ghajar J (2007) Guidelines for the management of severe traumatic brain injury. Introduction. J Neurotrauma 24(Suppl 1):S1-2PubMedCrossRef Carney N, Ghajar J (2007) Guidelines for the management of severe traumatic brain injury. Introduction. J Neurotrauma 24(Suppl 1):S1-2PubMedCrossRef
13.
go back to reference Carney N, Totten AM, O’Reilly C, Ullman JS, Hawryluk GW, Bell MJ et al (2017) Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery 80(1):6–15PubMedCrossRef Carney N, Totten AM, O’Reilly C, Ullman JS, Hawryluk GW, Bell MJ et al (2017) Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery 80(1):6–15PubMedCrossRef
14.
go back to reference Cnossen MC, Scholten AC, Lingsma HF, Synnot A, Tavender E, Gantner D et al (2016) Adherence to guidelines in adult patients with traumatic brain injury: a living systematic review. J Neurotrauma Cnossen MC, Scholten AC, Lingsma HF, Synnot A, Tavender E, Gantner D et al (2016) Adherence to guidelines in adult patients with traumatic brain injury: a living systematic review. J Neurotrauma
15.
go back to reference Collin C, Wade DT, Davies S, Horne V (1988) The Barthel ADL index: a reliability study. Int Disabil Stud 10(2):61–63PubMedCrossRef Collin C, Wade DT, Davies S, Horne V (1988) The Barthel ADL index: a reliability study. Int Disabil Stud 10(2):61–63PubMedCrossRef
16.
go back to reference Corral L, Ventura JL, Herrero JI, Monfort JL, Juncadella M, Gabarros A et al (2007) Improvement in GOS and GOSE scores 6 and 12 months after severe traumatic brain injury. Brain Inj 21(12):1225–1231PubMedCrossRef Corral L, Ventura JL, Herrero JI, Monfort JL, Juncadella M, Gabarros A et al (2007) Improvement in GOS and GOSE scores 6 and 12 months after severe traumatic brain injury. Brain Inj 21(12):1225–1231PubMedCrossRef
17.
go back to reference Corrigan JD, Hammond FM (2013) Traumatic brain injury as a chronic health condition. Arch Phys Med Rehabil 94(6):1199–1201PubMedCrossRef Corrigan JD, Hammond FM (2013) Traumatic brain injury as a chronic health condition. Arch Phys Med Rehabil 94(6):1199–1201PubMedCrossRef
18.
go back to reference DʼArcy RC, Lindsay DS, Song X, Gawryluk JR, Greene D, Mayo C et al (2016) Long-term motor recovery after severe traumatic brain injury: beyond established limits. J Head Trauma Rehabil 31(5):E50-8PubMedCrossRef DʼArcy RC, Lindsay DS, Song X, Gawryluk JR, Greene D, Mayo C et al (2016) Long-term motor recovery after severe traumatic brain injury: beyond established limits. J Head Trauma Rehabil 31(5):E50-8PubMedCrossRef
19.
20.
go back to reference Elbourn E, Kenny B, Power E, Honan C, McDonald S, Tate R et al (2019) Discourse recovery after severe traumatic brain injury: exploring the first year. Brain Inj 33(2):143–159PubMedCrossRef Elbourn E, Kenny B, Power E, Honan C, McDonald S, Tate R et al (2019) Discourse recovery after severe traumatic brain injury: exploring the first year. Brain Inj 33(2):143–159PubMedCrossRef
21.
22.
go back to reference Forslund MV, Perrin PB, Roe C, Sigurdardottir S, Hellstrom T, Berntsen SA et al (2019) Global outcome trajectories up to 10 years after moderate to severe traumatic brain injury. Front Neurol 10:219PubMedPubMedCentralCrossRef Forslund MV, Perrin PB, Roe C, Sigurdardottir S, Hellstrom T, Berntsen SA et al (2019) Global outcome trajectories up to 10 years after moderate to severe traumatic brain injury. Front Neurol 10:219PubMedPubMedCentralCrossRef
23.
go back to reference Fuller GW, Ransom J, Mandrekar J, Brown AW (2016) Long-term survival following traumatic brain injury: a population-based parametric survival analysis. Neuroepidemiology 47(1):1–10PubMedCrossRef Fuller GW, Ransom J, Mandrekar J, Brown AW (2016) Long-term survival following traumatic brain injury: a population-based parametric survival analysis. Neuroepidemiology 47(1):1–10PubMedCrossRef
24.
25.
go back to reference Gomez-Hernandez R, Max JE, Kosier T, Paradiso S, Robinson RG (1997) Social impairment and depression after traumatic brain injury. Arch Phys Med Rehabil 78(12):1321–1326PubMedCrossRef Gomez-Hernandez R, Max JE, Kosier T, Paradiso S, Robinson RG (1997) Social impairment and depression after traumatic brain injury. Arch Phys Med Rehabil 78(12):1321–1326PubMedCrossRef
26.
go back to reference Gouello G, Hamel O, Asehnoune K, Bord E, Robert R, Buffenoir K (2014) Study of the long-term results of decompressive craniectomy after severe traumatic brain injury based on a series of 60 consecutive cases. Sci World J 2014:207585CrossRef Gouello G, Hamel O, Asehnoune K, Bord E, Robert R, Buffenoir K (2014) Study of the long-term results of decompressive craniectomy after severe traumatic brain injury based on a series of 60 consecutive cases. Sci World J 2014:207585CrossRef
27.
go back to reference Grauwmeijer E, Heijenbrok-Kal MH, Haitsma IK, Ribbers GM (2012) A prospective study on employment outcome 3 years after moderate to severe traumatic brain injury. Arch Phys Med Rehabil 93(6):993–999PubMedCrossRef Grauwmeijer E, Heijenbrok-Kal MH, Haitsma IK, Ribbers GM (2012) A prospective study on employment outcome 3 years after moderate to severe traumatic brain injury. Arch Phys Med Rehabil 93(6):993–999PubMedCrossRef
28.
go back to reference Grauwmeijer E, Heijenbrok-Kal MH, Haitsma IK, Ribbers GM (2017) Employment outcome ten years after moderate to severe traumatic brain injury: a prospective cohort study. J Neurotrauma 34(17):2575–2581PubMedCrossRef Grauwmeijer E, Heijenbrok-Kal MH, Haitsma IK, Ribbers GM (2017) Employment outcome ten years after moderate to severe traumatic brain injury: a prospective cohort study. J Neurotrauma 34(17):2575–2581PubMedCrossRef
29.
go back to reference Gray DS (2000) Slow-to-recover severe traumatic brain injury: a review of outcomes and rehabilitation effectiveness. Brain Inj 14(11):1003–1014PubMedCrossRef Gray DS (2000) Slow-to-recover severe traumatic brain injury: a review of outcomes and rehabilitation effectiveness. Brain Inj 14(11):1003–1014PubMedCrossRef
30.
go back to reference Grille P, Tommasino N (2015) Decompressive craniectomy in severe traumatic brain injury: prognostic factors and complications. Rev Bras Ter Intensiva 27(2):113–118PubMedPubMedCentralCrossRef Grille P, Tommasino N (2015) Decompressive craniectomy in severe traumatic brain injury: prognostic factors and complications. Rev Bras Ter Intensiva 27(2):113–118PubMedPubMedCentralCrossRef
31.
go back to reference Harrison-Felix C, Kreider SE, Arango-Lasprilla JC, Brown AW, Dijkers MP, Hammond FM et al (2012) Life expectancy following rehabilitation: a NIDRR Traumatic Brain Injury Model Systems study. J Head Trauma Rehabil 27(6):E69-80PubMedCrossRef Harrison-Felix C, Kreider SE, Arango-Lasprilla JC, Brown AW, Dijkers MP, Hammond FM et al (2012) Life expectancy following rehabilitation: a NIDRR Traumatic Brain Injury Model Systems study. J Head Trauma Rehabil 27(6):E69-80PubMedCrossRef
32.
go back to reference Hayden JA, van der Windt DA, Cartwright JL, Cote P, Bombardier C (2013) Assessing bias in studies of prognostic factors. Ann Intern Med 158(4):280–286PubMedCrossRef Hayden JA, van der Windt DA, Cartwright JL, Cote P, Bombardier C (2013) Assessing bias in studies of prognostic factors. Ann Intern Med 158(4):280–286PubMedCrossRef
33.
go back to reference Hayden JA, van der Windt DA, Cartwright JL, Côté P, Bombardier C (2013) Assessing bias in studies of prognostic factors. Ann Intern Med 158:280–6PubMedCrossRef Hayden JA, van der Windt DA, Cartwright JL, Côté P, Bombardier C (2013) Assessing bias in studies of prognostic factors. Ann Intern Med 158:280–6PubMedCrossRef
34.
go back to reference Ho KM (2018) Predicting outcomes after severe traumatic brain injury: science, humanity or both? J Neurosurg Sci 62(5):593–598PubMedCrossRef Ho KM (2018) Predicting outcomes after severe traumatic brain injury: science, humanity or both? J Neurosurg Sci 62(5):593–598PubMedCrossRef
35.
go back to reference Honeybul S (2020) Balancing the short-term benefits and long-term outcomes of decompressive craniectomy for severe traumatic brain injury. Expert Rev Neurother 20(4):333–340PubMedCrossRef Honeybul S (2020) Balancing the short-term benefits and long-term outcomes of decompressive craniectomy for severe traumatic brain injury. Expert Rev Neurother 20(4):333–340PubMedCrossRef
36.
go back to reference Honeybul S, Janzen C, Kruger K, Ho KM (2013) Decompressive craniectomy for severe traumatic brain injury: is life worth living? J Neurosurg 119(6):1566–1575PubMedCrossRef Honeybul S, Janzen C, Kruger K, Ho KM (2013) Decompressive craniectomy for severe traumatic brain injury: is life worth living? J Neurosurg 119(6):1566–1575PubMedCrossRef
37.
go back to reference Hopman WM, Towheed T, Anastassiades T et al (2000) Canadian normative data for the SF-36 health survey. Canadian Multicentre Osteoporosis Study Research Group. CMAJ 163(3):265–271 Hopman WM, Towheed T, Anastassiades T et al (2000) Canadian normative data for the SF-36 health survey. Canadian Multicentre Osteoporosis Study Research Group. CMAJ 163(3):265–271
38.
go back to reference Jaeger M, Deiana G, Nash S, Bar JY, Cotton F, Dailler F et al (2014) Prognostic factors of long-term outcome in cases of severe traumatic brain injury. Ann Phys Rehabil Med 57(6–7):436–451PubMedCrossRef Jaeger M, Deiana G, Nash S, Bar JY, Cotton F, Dailler F et al (2014) Prognostic factors of long-term outcome in cases of severe traumatic brain injury. Ann Phys Rehabil Med 57(6–7):436–451PubMedCrossRef
39.
go back to reference Jennett B, Bond M (1975) Assessment of outcome after severe brain damage. Lancet (London, England) 1(7905):480–484CrossRef Jennett B, Bond M (1975) Assessment of outcome after severe brain damage. Lancet (London, England) 1(7905):480–484CrossRef
40.
go back to reference Jennett B, Snoek J, Bond MR, Brooks N (1981) Disability after severe head injury: observations on the use of the Glasgow Outcome Scale. J Neurol Neurosurg Psychiatry 44(4):285–293PubMedPubMedCentralCrossRef Jennett B, Snoek J, Bond MR, Brooks N (1981) Disability after severe head injury: observations on the use of the Glasgow Outcome Scale. J Neurol Neurosurg Psychiatry 44(4):285–293PubMedPubMedCentralCrossRef
41.
go back to reference Jourdan C, Bayen E, Darnoux E, Ghout I, Azerad S, Ruet A et al (2015) Patterns of post-acute health care utilization after a severe traumatic brain injury: results from the PariS-TBI cohort. Brain Inj 29(6):701–708PubMedCrossRef Jourdan C, Bayen E, Darnoux E, Ghout I, Azerad S, Ruet A et al (2015) Patterns of post-acute health care utilization after a severe traumatic brain injury: results from the PariS-TBI cohort. Brain Inj 29(6):701–708PubMedCrossRef
42.
go back to reference Jourdan C, Bayen E, Vallat-Azouvi C, Ghout I, Darnoux E, Azerad S et al (2017) Late functional changes post-severe traumatic brain injury are related to community reentry support: results from the PariS-TBI cohort. J Head Trauma Rehabil 32(5):E26-e34PubMedCrossRef Jourdan C, Bayen E, Vallat-Azouvi C, Ghout I, Darnoux E, Azerad S et al (2017) Late functional changes post-severe traumatic brain injury are related to community reentry support: results from the PariS-TBI cohort. J Head Trauma Rehabil 32(5):E26-e34PubMedCrossRef
43.
go back to reference Keith RA, Granger CV, Hamilton BB, Sherwin FS (1987) The functional independence measure: a new tool for rehabilitation. Adv Clin Rehabil 1:6–18PubMed Keith RA, Granger CV, Hamilton BB, Sherwin FS (1987) The functional independence measure: a new tool for rehabilitation. Adv Clin Rehabil 1:6–18PubMed
44.
go back to reference Konigs M, Beurskens EA, Snoep L, Scherder EJ, Oosterlaan J (2018) Effects of timing and intensity of neurorehabilitation on functional outcome after traumatic brain injury: a systematic review and meta-analysis. Arch Phys Med Rehabil 99(6):1149–59.e1PubMedCrossRef Konigs M, Beurskens EA, Snoep L, Scherder EJ, Oosterlaan J (2018) Effects of timing and intensity of neurorehabilitation on functional outcome after traumatic brain injury: a systematic review and meta-analysis. Arch Phys Med Rehabil 99(6):1149–59.e1PubMedCrossRef
45.
go back to reference Krishnamoorthy V, Vavilala MS, Mills B, Rowhani-Rahbar A (2015) Demographic and clinical risk factors associated with hospital mortality after isolated severe traumatic brain injury: a cohort study. J Intensive Care 3(1):46PubMedPubMedCentralCrossRef Krishnamoorthy V, Vavilala MS, Mills B, Rowhani-Rahbar A (2015) Demographic and clinical risk factors associated with hospital mortality after isolated severe traumatic brain injury: a cohort study. J Intensive Care 3(1):46PubMedPubMedCentralCrossRef
46.
go back to reference Kulesza B, Nogalski A, Kulesza T, Prystupa A (2015) Prognostic factors in traumatic brain injury and their association with outcome. J Pre-Clin Clin Res 9(2):163–166CrossRef Kulesza B, Nogalski A, Kulesza T, Prystupa A (2015) Prognostic factors in traumatic brain injury and their association with outcome. J Pre-Clin Clin Res 9(2):163–166CrossRef
47.
go back to reference Lesimple B, Caron E, Lefort M, Debarle C, Pelegrini-Issac M, Cassereau D et al (2019) Long-term cognitive disability after traumatic brain injury: contribution of the DEX relative questionnaires. Neuropsychol Rehab: 1–20 Lesimple B, Caron E, Lefort M, Debarle C, Pelegrini-Issac M, Cassereau D et al (2019) Long-term cognitive disability after traumatic brain injury: contribution of the DEX relative questionnaires. Neuropsychol Rehab: 1–20
48.
go back to reference Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. Bmj. 339:b2700PubMedPubMedCentralCrossRef Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. Bmj. 339:b2700PubMedPubMedCentralCrossRef
49.
go back to reference Maas AIR, Menon DK, Adelson PD, Andelic N, Bell MJ, Belli A, Bragge P, Brazinova A, Büki A, Chesnut RM, Citerio G, Coburn M, Cooper DJ, Crowder AT, Czeiter E, Czosnyka M, Diaz-Arrastia R, Dreier JP, Duhaime AC, Ercole A, van Essen TA, Feigin VL, Gao G, Giacino J, Gonzalez-Lara LE, Gruen RL, Gupta D, Hartings JA, Hill S, Jiang JY, Ketharanathan N, Kompanje EJO, Lanyon L, Laureys S, Lecky F, Levin H, Lingsma HF, Maegele M, Majdan M, Manley G, Marsteller J, Mascia L, McFadyen C, Mondello S, Newcombe V, Palotie A, Parizel PM, Peul W, Piercy J, Polinder S, Puybasset L, Rasmussen TE, Rossaint R, Smielewski P, Söderberg J, Stanworth SJ, Stein MB, von Steinbüchel N, Stewart W, Steyerberg EW, Stocchetti N, Synnot A, Te Ao B, Tenovuo O, Theadom A, Tibboel D, Videtta W, Wang KKW, Williams WH, Wilson L, Yaffe K (2017) InTBIR Participants and Investigators. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol 16(12):987–1048. https://doi.org/10.1016/S1474-4422(17)30371-X Maas AIR, Menon DK, Adelson PD, Andelic N, Bell MJ, Belli A, Bragge P, Brazinova A, Büki A, Chesnut RM, Citerio G, Coburn M, Cooper DJ, Crowder AT, Czeiter E, Czosnyka M, Diaz-Arrastia R, Dreier JP, Duhaime AC, Ercole A, van Essen TA, Feigin VL, Gao G, Giacino J, Gonzalez-Lara LE, Gruen RL, Gupta D, Hartings JA, Hill S, Jiang JY, Ketharanathan N, Kompanje EJO, Lanyon L, Laureys S, Lecky F, Levin H, Lingsma HF, Maegele M, Majdan M, Manley G, Marsteller J, Mascia L, McFadyen C, Mondello S, Newcombe V, Palotie A, Parizel PM, Peul W, Piercy J, Polinder S, Puybasset L, Rasmussen TE, Rossaint R, Smielewski P, Söderberg J, Stanworth SJ, Stein MB, von Steinbüchel N, Stewart W, Steyerberg EW, Stocchetti N, Synnot A, Te Ao B, Tenovuo O, Theadom A, Tibboel D, Videtta W, Wang KKW, Williams WH, Wilson L, Yaffe K (2017) InTBIR Participants and Investigators. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol 16(12):987–1048. https://​doi.​org/​10.​1016/​S1474-4422(17)30371-X
50.
go back to reference Mahoney FI, Barthel DW (1965) Functional evaluation: the Barthel index. Md State Med J 14:61–65PubMed Mahoney FI, Barthel DW (1965) Functional evaluation: the Barthel index. Md State Med J 14:61–65PubMed
51.
go back to reference Marklund N, Bellander BM, Godbolt AK, Levin H, McCrory P, Thelin EP (2019) Treatments and rehabilitation in the acute and chronic state of traumatic brain injury. J Intern Med 285(6):608–623PubMedPubMedCentralCrossRef Marklund N, Bellander BM, Godbolt AK, Levin H, McCrory P, Thelin EP (2019) Treatments and rehabilitation in the acute and chronic state of traumatic brain injury. J Intern Med 285(6):608–623PubMedPubMedCentralCrossRef
53.
go back to reference Mauritz W, Wilbacher I, Leitgeb J, Majdan M, Janciak I, Brazinova A et al (2011) One-year outcome and course of recovery after severe traumatic brain injury. Europ J Trauma Emerg Surg 37(4):387–395CrossRef Mauritz W, Wilbacher I, Leitgeb J, Majdan M, Janciak I, Brazinova A et al (2011) One-year outcome and course of recovery after severe traumatic brain injury. Europ J Trauma Emerg Surg 37(4):387–395CrossRef
54.
go back to reference McMillan TM, Teasdale GM, Stewart E (2012) Disability in young people and adults after head injury: 12–14 year follow-up of a prospective cohort. J Neurol Neurosurg Psychiatry 83(11):1086–1091PubMedCrossRef McMillan TM, Teasdale GM, Stewart E (2012) Disability in young people and adults after head injury: 12–14 year follow-up of a prospective cohort. J Neurol Neurosurg Psychiatry 83(11):1086–1091PubMedCrossRef
55.
go back to reference McMillan TM, Teasdale GM, Weir CJ, Stewart E (2011) Death after head injury: the 13 year outcome of a case control study. J Neurol Neurosurg Psychiatry 82(8):931–935PubMedCrossRef McMillan TM, Teasdale GM, Weir CJ, Stewart E (2011) Death after head injury: the 13 year outcome of a case control study. J Neurol Neurosurg Psychiatry 82(8):931–935PubMedCrossRef
56.
go back to reference Mollayeva T, Mollayeva S, Pacheco N, D’Souza A, Colantonio A (2019) The course and prognostic factors of cognitive outcomes after traumatic brain injury: a systematic review and meta-analysis. Neurosci Biobehav Rev 99:198–250PubMedCrossRef Mollayeva T, Mollayeva S, Pacheco N, D’Souza A, Colantonio A (2019) The course and prognostic factors of cognitive outcomes after traumatic brain injury: a systematic review and meta-analysis. Neurosci Biobehav Rev 99:198–250PubMedCrossRef
57.
go back to reference Morgalla MH, Will BE, Roser F, Tatagiba M (2008) Do long-term results justify decompressive craniectomy after severe traumatic brain injury? J Neurosurg 109(4):685–690PubMedCrossRef Morgalla MH, Will BE, Roser F, Tatagiba M (2008) Do long-term results justify decompressive craniectomy after severe traumatic brain injury? J Neurosurg 109(4):685–690PubMedCrossRef
58.
go back to reference Moskowitz J, Quinn T, Khan MW, Shutter L, Goldberg R, Col N et al (2018) Should we use the IMPACT-model for the outcome prognostication of TBI patients? A qualitative study assessing physicians’ perceptions. MDM Policy Pract 3(1):2381468318757987PubMedPubMedCentral Moskowitz J, Quinn T, Khan MW, Shutter L, Goldberg R, Col N et al (2018) Should we use the IMPACT-model for the outcome prognostication of TBI patients? A qualitative study assessing physicians’ perceptions. MDM Policy Pract 3(1):2381468318757987PubMedPubMedCentral
59.
go back to reference MRC CRASH Trial Collaborators, Perel P, Arango M, Clayton T, Edwards P, Komolafe E, Poccock S, Roberts I, Shakur H, Steyerberg E, Yutthakasemsunt S (2008) Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ 336(7641):425–429. https://doi.org/10.1136/bmj.39461.643438.25 MRC CRASH Trial Collaborators, Perel P, Arango M, Clayton T, Edwards P, Komolafe E, Poccock S, Roberts I, Shakur H, Steyerberg E, Yutthakasemsunt S (2008) Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ 336(7641):425–429. https://​doi.​org/​10.​1136/​bmj.​39461.​643438.​25
61.
go back to reference Perel P, Arango M, Clayton T, Edwards P, Komolafe E, Poccock S et al (2008) Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ 336(7641):425–429PubMedCrossRef Perel P, Arango M, Clayton T, Edwards P, Komolafe E, Poccock S et al (2008) Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ 336(7641):425–429PubMedCrossRef
63.
go back to reference Polinder S, Haagsma JA, van Klaveren D, Steyerberg EW, van Beeck EF (2015) Health-related quality of life after TBI: a systematic review of study design, instruments, measurement properties, and outcome. Popul Health Metrics 13:4CrossRef Polinder S, Haagsma JA, van Klaveren D, Steyerberg EW, van Beeck EF (2015) Health-related quality of life after TBI: a systematic review of study design, instruments, measurement properties, and outcome. Popul Health Metrics 13:4CrossRef
64.
go back to reference Ratan RR, Schiff ND (2018) Protecting and repairing the brain: central and peripheral strategies define the new rehabilitation following traumatic brain injury. Curr Opin Neurol 31(6):669–671PubMedCrossRef Ratan RR, Schiff ND (2018) Protecting and repairing the brain: central and peripheral strategies define the new rehabilitation following traumatic brain injury. Curr Opin Neurol 31(6):669–671PubMedCrossRef
65.
go back to reference Roozenbeek B, Chiu Y-L, Lingsma HF, Gerber LM, Steyerberg EW, Ghajar J et al (2012) Predicting 14-day mortality after severe traumatic brain injury: application of the IMPACT models in the brain trauma foundation TBI-trac® New York State database. J Neurotrauma 29(7):1306–1312PubMedPubMedCentralCrossRef Roozenbeek B, Chiu Y-L, Lingsma HF, Gerber LM, Steyerberg EW, Ghajar J et al (2012) Predicting 14-day mortality after severe traumatic brain injury: application of the IMPACT models in the brain trauma foundation TBI-trac® New York State database. J Neurotrauma 29(7):1306–1312PubMedPubMedCentralCrossRef
66.
go back to reference Rapoport M, McCauley S, Levin H, Song J, Feinstein A (2002) The role of injury severity in neurobehavioral outcome 3 months after traumatic brain injury. Neuropsychiatry Neuropsychol Behav Neurol 15(2):123–132PubMed Rapoport M, McCauley S, Levin H, Song J, Feinstein A (2002) The role of injury severity in neurobehavioral outcome 3 months after traumatic brain injury. Neuropsychiatry Neuropsychol Behav Neurol 15(2):123–132PubMed
67.
go back to reference Rosenfeld JV, Maas AI, Bragge P, Morganti-Kossmann MC, Manley GT, Gruen RL (2012) Early management of severe traumatic brain injury. Lancet (London, England) 380(9847):1088–1098CrossRef Rosenfeld JV, Maas AI, Bragge P, Morganti-Kossmann MC, Manley GT, Gruen RL (2012) Early management of severe traumatic brain injury. Lancet (London, England) 380(9847):1088–1098CrossRef
68.
go back to reference Ruet A, Bayen E, Jourdan C, Ghout I, Meaude L, Lalanne A et al (2019) A detailed overview of long-term outcomes in severe traumatic brain injury eight years post-injury. Front Neurol 10:120PubMedPubMedCentralCrossRef Ruet A, Bayen E, Jourdan C, Ghout I, Meaude L, Lalanne A et al (2019) A detailed overview of long-term outcomes in severe traumatic brain injury eight years post-injury. Front Neurol 10:120PubMedPubMedCentralCrossRef
69.
go back to reference Salas CE, Casassus M, Rowlands L, Pimm S, Flanagan DAJ (2018) “Relating through sameness”: a qualitative study of friendship and social isolation in chronic traumatic brain injury. Neuropsychol Rehabil 28(7):1161–1178PubMedCrossRef Salas CE, Casassus M, Rowlands L, Pimm S, Flanagan DAJ (2018) “Relating through sameness”: a qualitative study of friendship and social isolation in chronic traumatic brain injury. Neuropsychol Rehabil 28(7):1161–1178PubMedCrossRef
70.
go back to reference Sandhaug M, Andelic N, Langhammer B, Mygland A (2015) Functional level during the first 2 years after moderate and severe traumatic brain injury. Brain Inj 29(12):1431–1438PubMedCrossRef Sandhaug M, Andelic N, Langhammer B, Mygland A (2015) Functional level during the first 2 years after moderate and severe traumatic brain injury. Brain Inj 29(12):1431–1438PubMedCrossRef
71.
go back to reference Schwarzbold M, Diaz A, Martins ET, Rufino A, Amante LN, Thais ME et al (2008) Psychiatric disorders and traumatic brain injury. Neuropsychiatr Dis Treat 4(4):797–816PubMedPubMedCentral Schwarzbold M, Diaz A, Martins ET, Rufino A, Amante LN, Thais ME et al (2008) Psychiatric disorders and traumatic brain injury. Neuropsychiatr Dis Treat 4(4):797–816PubMedPubMedCentral
72.
go back to reference Soberg HL, Roe C, Anke A, Arango-Lasprilla JC, Skandsen T, Sveen U et al (2013) Health-related quality of life 12 months after severe traumatic brain injury: a prospective nationwide cohort study. J Rehabil Med 45(8):785–791PubMedCrossRef Soberg HL, Roe C, Anke A, Arango-Lasprilla JC, Skandsen T, Sveen U et al (2013) Health-related quality of life 12 months after severe traumatic brain injury: a prospective nationwide cohort study. J Rehabil Med 45(8):785–791PubMedCrossRef
73.
go back to reference Stålnacke B-M, Saveman B-I, Stenberg M (2019) Long-term follow-up of disability, cognitive, and emotional impairments after severe traumatic brain injury. Behav Neurol 2019:9216931PubMedPubMedCentralCrossRef Stålnacke B-M, Saveman B-I, Stenberg M (2019) Long-term follow-up of disability, cognitive, and emotional impairments after severe traumatic brain injury. Behav Neurol 2019:9216931PubMedPubMedCentralCrossRef
74.
go back to reference Steyerberg EW, Mushkudiani N, Perel P, Butcher I, Lu J, McHugh GS et al (2008) Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics. PLoS Med 5(8):e165 (discussion e)PubMedPubMedCentralCrossRef Steyerberg EW, Mushkudiani N, Perel P, Butcher I, Lu J, McHugh GS et al (2008) Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics. PLoS Med 5(8):e165 (discussion e)PubMedPubMedCentralCrossRef
75.
go back to reference Stocchetti N, Poole D, Okonkwo DO (2018) Intracranial pressure thresholds in severe traumatic brain injury: we are not sure: prudent clinical practice despite dogma or nihilism. Intensive Care Med 44(8):1321–1323PubMedCrossRef Stocchetti N, Poole D, Okonkwo DO (2018) Intracranial pressure thresholds in severe traumatic brain injury: we are not sure: prudent clinical practice despite dogma or nihilism. Intensive Care Med 44(8):1321–1323PubMedCrossRef
76.
go back to reference Stocchetti N, Zanier ER (2016) Chronic impact of traumatic brain injury on outcome and quality of life: a narrative review. Critical care (London, England) 20(1):148CrossRef Stocchetti N, Zanier ER (2016) Chronic impact of traumatic brain injury on outcome and quality of life: a narrative review. Critical care (London, England) 20(1):148CrossRef
77.
go back to reference Syddall HE, Martin HJ, Harwood RH, Cooper C, Aihie SA (2009) The SF-36: a simple, effective measure of mobility-disability for epidemiological studies. J Nutr Health Aging 13(1):57–62PubMedPubMedCentralCrossRef Syddall HE, Martin HJ, Harwood RH, Cooper C, Aihie SA (2009) The SF-36: a simple, effective measure of mobility-disability for epidemiological studies. J Nutr Health Aging 13(1):57–62PubMedPubMedCentralCrossRef
78.
go back to reference Taw BB, Lam AC, Ho FL, Hung KN, Lui WM, Leung GK (2012) Functional survival after acute care for severe head injury at a designated trauma center in Hong Kong. Asian J Surg 35(3):117–122PubMedCrossRef Taw BB, Lam AC, Ho FL, Hung KN, Lui WM, Leung GK (2012) Functional survival after acute care for severe head injury at a designated trauma center in Hong Kong. Asian J Surg 35(3):117–122PubMedCrossRef
80.
go back to reference Timmer ML, Jacobs B, Schonherr MC, Spikman JM, van der Naalt J (2020) The spectrum of long-term behavioral disturbances and provided care after traumatic brain injury 11(246) Timmer ML, Jacobs B, Schonherr MC, Spikman JM, van der Naalt J (2020) The spectrum of long-term behavioral disturbances and provided care after traumatic brain injury 11(246)
81.
go back to reference Ulfarsson T, Arnar Gudnason G, Rosen T, Blomstrand C, Sunnerhagen KS, Lundgren-Nilsson A et al (2013) Pituitary function and functional outcome in adults after severe traumatic brain injury: the long-term perspective. J Neurotrauma 30(4):271–280PubMedCrossRef Ulfarsson T, Arnar Gudnason G, Rosen T, Blomstrand C, Sunnerhagen KS, Lundgren-Nilsson A et al (2013) Pituitary function and functional outcome in adults after severe traumatic brain injury: the long-term perspective. J Neurotrauma 30(4):271–280PubMedCrossRef
82.
go back to reference Ulfarsson T, Lundgren-Nilsson Å, Blomstrand C, Jakobsson KE, Odén A, Nilsson M et al (2014) Ten-year mortality after severe traumatic brain injury in western Sweden: a case control study. Brain Inj 28(13–14):1675–1681PubMedCrossRef Ulfarsson T, Lundgren-Nilsson Å, Blomstrand C, Jakobsson KE, Odén A, Nilsson M et al (2014) Ten-year mortality after severe traumatic brain injury in western Sweden: a case control study. Brain Inj 28(13–14):1675–1681PubMedCrossRef
83.
go back to reference van Dijck J, Bartels R, Lavrijsen JCM, Ribbers GM, Kompanje EJO, Peul WC (2019) The patient with severe traumatic brain injury: clinical decision-making: the first 60 min and beyond. Curr Opin Crit Care 25(6):622–629PubMedCrossRef van Dijck J, Bartels R, Lavrijsen JCM, Ribbers GM, Kompanje EJO, Peul WC (2019) The patient with severe traumatic brain injury: clinical decision-making: the first 60 min and beyond. Curr Opin Crit Care 25(6):622–629PubMedCrossRef
84.
go back to reference van Dijck JTJM, Bartels RHMA, Lavrijsen JCM, Ribbers GM, Kompanje EJO, Peul WC et al (2019) The patient with severe traumatic brain injury: clinical decision-making: the first 60 min and beyond. Curr Opin Crit Care 25(6):622–629PubMedCrossRef van Dijck JTJM, Bartels RHMA, Lavrijsen JCM, Ribbers GM, Kompanje EJO, Peul WC et al (2019) The patient with severe traumatic brain injury: clinical decision-making: the first 60 min and beyond. Curr Opin Crit Care 25(6):622–629PubMedCrossRef
85.
go back to reference van Essen TA, den Boogert HF, Cnossen MC, de Ruiter GCW, Haitsma I, Polinder S et al (2019) Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study. Acta Neurochir 161(3):435–449PubMedCrossRef van Essen TA, den Boogert HF, Cnossen MC, de Ruiter GCW, Haitsma I, Polinder S et al (2019) Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study. Acta Neurochir 161(3):435–449PubMedCrossRef
86.
go back to reference van Essen TA, de Ruiter GC, Kho KH, Peul WC (2017) Neurosurgical treatment variation of traumatic brain injury: evaluation of acute subdural hematoma management in Belgium and The Netherlands. J Neurotrauma 34(4):881–889PubMedCrossRef van Essen TA, de Ruiter GC, Kho KH, Peul WC (2017) Neurosurgical treatment variation of traumatic brain injury: evaluation of acute subdural hematoma management in Belgium and The Netherlands. J Neurotrauma 34(4):881–889PubMedCrossRef
87.
go back to reference van Veen E, van der Jagt M, Citerio G, Stocchetti N, Epker JL, Gommers D et al (2020) End-of-life practices in traumatic brain injury patients: report of a questionnaire from the CENTER-TBI study. J Crit Care 58:78–88PubMedCrossRef van Veen E, van der Jagt M, Citerio G, Stocchetti N, Epker JL, Gommers D et al (2020) End-of-life practices in traumatic brain injury patients: report of a questionnaire from the CENTER-TBI study. J Crit Care 58:78–88PubMedCrossRef
88.
go back to reference Volovici V, Ercole A, Citerio G, Stocchetti N, Haitsma IK, Huijben JA et al (2019) Variation in guideline implementation and adherence regarding severe traumatic brain injury treatment: a CENTER-TBI survey study in Europe. World Neurosurg 125:e515–e520PubMedCrossRef Volovici V, Ercole A, Citerio G, Stocchetti N, Haitsma IK, Huijben JA et al (2019) Variation in guideline implementation and adherence regarding severe traumatic brain injury treatment: a CENTER-TBI survey study in Europe. World Neurosurg 125:e515–e520PubMedCrossRef
89.
go back to reference von Steinbuechel N, Petersen C, Bullinger M (2005) Assessment of health-related quality of life in persons after traumatic brain injury—development of the Qolibri, a specific measure. Acta Neurochir Suppl 93:43–49CrossRef von Steinbuechel N, Petersen C, Bullinger M (2005) Assessment of health-related quality of life in persons after traumatic brain injury—development of the Qolibri, a specific measure. Acta Neurochir Suppl 93:43–49CrossRef
90.
go back to reference Wabl R, Williamson CA, Pandey AS, Rajajee V (2018) Long-term and delayed functional recovery in patients with severe cerebrovascular and traumatic brain injury requiring tracheostomy. J Neurosurg: 1–8 Wabl R, Williamson CA, Pandey AS, Rajajee V (2018) Long-term and delayed functional recovery in patients with severe cerebrovascular and traumatic brain injury requiring tracheostomy. J Neurosurg: 1–8
91.
go back to reference Ware J Jr, Kosinski M, Keller SD (1996) A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care 34(3):220–233PubMedCrossRef Ware J Jr, Kosinski M, Keller SD (1996) A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care 34(3):220–233PubMedCrossRef
92.
go back to reference Wilkins TE, Beers SR, Borrasso AJ, Brooks J, Mesley M, Puffer R et al (2019) Favorable functional recovery in severe traumatic brain injury survivors beyond six months. J Neurotrauma 36(22):3158–3163PubMedPubMedCentralCrossRef Wilkins TE, Beers SR, Borrasso AJ, Brooks J, Mesley M, Puffer R et al (2019) Favorable functional recovery in severe traumatic brain injury survivors beyond six months. J Neurotrauma 36(22):3158–3163PubMedPubMedCentralCrossRef
93.
go back to reference Williams RF, Magnotti LJ, Croce MA, Hargraves BB, Fischer PE, Schroeppel TJ et al (2009) Impact of decompressive craniectomy on functional outcome after severe traumatic brain injury. J Trauma 66(6):1570–4 (discussion 4–6)PubMed Williams RF, Magnotti LJ, Croce MA, Hargraves BB, Fischer PE, Schroeppel TJ et al (2009) Impact of decompressive craniectomy on functional outcome after severe traumatic brain injury. J Trauma 66(6):1570–4 (discussion 4–6)PubMed
94.
go back to reference Wilson L, Marsden-Loftus I, Koskinen S, Bakx W, Bullinger M, Formisano R et al (2017) Interpreting quality of life after brain injury scores: cross-walk with the short form-36. J Neurotrauma 34(1):59–65PubMedCrossRef Wilson L, Marsden-Loftus I, Koskinen S, Bakx W, Bullinger M, Formisano R et al (2017) Interpreting quality of life after brain injury scores: cross-walk with the short form-36. J Neurotrauma 34(1):59–65PubMedCrossRef
95.
go back to reference Wilson L, Stewart W, Dams-O’Connor K, Diaz-Arrastia R, Horton L, Menon DK et al (2017) The chronic and evolving neurological consequences of traumatic brain injury. Lancet Neurol 16(10):813–825PubMedCrossRef Wilson L, Stewart W, Dams-O’Connor K, Diaz-Arrastia R, Horton L, Menon DK et al (2017) The chronic and evolving neurological consequences of traumatic brain injury. Lancet Neurol 16(10):813–825PubMedCrossRef
96.
go back to reference Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370PubMedCrossRef Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370PubMedCrossRef
Metadata
Title
Long-term outcome after severe traumatic brain injury: a systematic literature review
Authors
Cassidy Q. B. Mostert
Ranjit D. Singh
Maxime Gerritsen
Erwin J. O. Kompanje
Gerard M. Ribbers
Wilco C. Peul
Jeroen T. J. M. van Dijck
Publication date
01-03-2022
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 3/2022
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-021-05086-6

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