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Critical Care
Published in: Critical Care 1/2019

Open Access 01-12-2019 | Central Nervous System Trauma | Editorial

How I monitor cerebral autoregulation

Authors: Samuel P. Klein, Bart Depreitere, Geert Meyfroidt

Published in: Critical Care | Issue 1/2019

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Excerpt

Cerebrovascular pressure autoregulation (CAR) protects the brain against changes in cerebral perfusion pressure (CPP) by adjusting the vascular resistance, to ensure a steady cerebral blood flow (CBF). The role of impaired CAR is well-described in the pathophysiology of traumatic brain injury (TBI), stroke, subarachnoid hemorrhage (SAH), and prematurity-related intracranial hemorrhage [1], but also in sepsis-associated brain dysfunction [2]. A clinical tool to assess CAR in real time may improve our understanding of the role of disturbed CBF in brain injury and systemic insults and open the door for personalized arterial blood pressure (ABP) manipulation to remain within the limits of active CAR [3]. …
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Metadata
Title
How I monitor cerebral autoregulation
Authors
Samuel P. Klein
Bart Depreitere
Geert Meyfroidt
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2019
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-019-2454-1

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