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Inflammation
Published in: Inflammation 3/2011

01-06-2011

Central Adiposity Rather Than Total Adiposity Measurements Are Specifically Involved in the Inflammatory Status from Healthy Young Adults

Authors: Helen Hermana M. Hermsdorff, M. Ángeles Zulet, Blanca Puchau, J. Alfredo Martínez

Published in: Inflammation | Issue 3/2011

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Abstract

This study assessed the potential association of some proinflammatory markers with adiposity (total vs. central) and metabolic features in young adults. Measurements included body composition, lifestyle features, blood biochemical, and selected inflammatory indicators on 154 healthy subjects (53 M/101 F; 21.5 ± 3 years; 22.1 ± 2.6 kg/m2). Those subjects with higher waist circumference (WC) and waist–hip ratio (WHR) showed higher (P < 0.05) C-reactive protein (CRP), complement C3, interleukin-6 (IL6), and retinol binding protein-4 (RBP4) concentrations, while only IL6 was positively associated with total body fat (%). Furthermore, CRP and RBP4 were higher in former/current smokers, as compared to never smokers (P < 0.05). Some indicators of glucose (homeostasis model assessment—insulin resistance) and lipid metabolism (total cholesterol/high density lipoprotein—cholesterol and triglycerides) were positively associated with the assayed inflammatory markers (P < 0.05). The findings of this cross-sectional study indicate that central adiposity-related indicators (WC/WHR) correlated better than those assessing total adiposity with plasma proinflammatory markers, which additionally were associated with lifestyle and metabolic features in healthy young adults.
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Metadata
Title
Central Adiposity Rather Than Total Adiposity Measurements Are Specifically Involved in the Inflammatory Status from Healthy Young Adults
Authors
Helen Hermana M. Hermsdorff
M. Ángeles Zulet
Blanca Puchau
J. Alfredo Martínez
Publication date
01-06-2011
Publisher
Springer US
Published in
Inflammation / Issue 3/2011
Print ISSN: 0360-3997
Electronic ISSN: 1573-2576
DOI
https://doi.org/10.1007/s10753-010-9219-y

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