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Published in: World Journal of Surgical Oncology 1/2014

Open Access 01-12-2014 | Case report

Cavernous hemangioma of the third ventricle: a case report and review of the literature

Authors: Moon-Soo Han, Kyung-Sub Moon, Kyung-Hwa Lee, Seul-Kee Kim, Shin Jung

Published in: World Journal of Surgical Oncology | Issue 1/2014

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Abstract

Background

Although cavernous hemangiomas (CHs) can be found anywhere in the central nervous system, CHs of the third ventricle have been reported in only 29 patients (including our case). In the current case report, we discuss the clinical characteristics and surgical outcome of CHs of the third ventricle.

Case presentation

A 64-year-old female was admitted to our emergency room with a sudden decreased level of consciousness. Brain imaging studies demonstrated a multi-lobulated hemorrhagic mass in the third ventricle. The lesion was removed via the transcallosal-interforniceal approach and pathologically diagnosed as CH. Postoperatively, the patient had a transient neurological deficit due to hypothalamic injury and recovered to the normal status at 2 months after the operation. In the review of 29 cases, the mean age of the patients was 40 years with a slight female preponderance (female/male, 17/12). The majority of the patients complained of a mass effect with signs of increased intracranial pressure; only one case was asymptomatic. Gross total resection was achieved in 81% of the cases. Around 80% of the patients were asymptomatic or improved from the initial symptoms. Mortality rate was 6.9% and the most common complication was hydrocephalus.

Conclusions

As demonstrated in the review of the previous reports, the outcome is favorable after surgical excision for CH of the third ventricle. Hence, surgical excision appears to be the treatment of choice for CH located in the third ventricle, which tends to grow rapidly resulting in a mass effect.
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Literature
1.
go back to reference Simard JM, Garcia-Bengochea F, Ballinger WE, Mickle JP, Quisling RG: Cavernous angioma: a review of 126 collected and 12 new clinical cases. Neurosurgery. 1986, 18 (2): 162-172. 10.1227/00006123-198602000-00008.CrossRefPubMed Simard JM, Garcia-Bengochea F, Ballinger WE, Mickle JP, Quisling RG: Cavernous angioma: a review of 126 collected and 12 new clinical cases. Neurosurgery. 1986, 18 (2): 162-172. 10.1227/00006123-198602000-00008.CrossRefPubMed
2.
go back to reference Voigt K, Yasargil MG: Cerebral cavernous haemangiomas or cavernomas. Incidence, pathology, localization, diagnosis, clinical features and treatment. Review of the literature and report of an unusual case. Neurochirurgia. 1976, 19 (2): 59-68.PubMed Voigt K, Yasargil MG: Cerebral cavernous haemangiomas or cavernomas. Incidence, pathology, localization, diagnosis, clinical features and treatment. Review of the literature and report of an unusual case. Neurochirurgia. 1976, 19 (2): 59-68.PubMed
3.
go back to reference Vaquero J, Carrillo R, Cabezudo J, Leunda G, Villoria F, Bravo G: Cavernous angiomas of the pineal region. Report of two cases. J Neurosurg. 1980, 53 (6): 833-835. 10.3171/jns.1980.53.6.0833.CrossRefPubMed Vaquero J, Carrillo R, Cabezudo J, Leunda G, Villoria F, Bravo G: Cavernous angiomas of the pineal region. Report of two cases. J Neurosurg. 1980, 53 (6): 833-835. 10.3171/jns.1980.53.6.0833.CrossRefPubMed
4.
go back to reference Pozzati E, Padovani R, Morrone B, Finizio F, Gaist G: Cerebral cavernous angiomas in children. J Neurosurg. 1980, 53 (6): 826-832. 10.3171/jns.1980.53.6.0826.CrossRefPubMed Pozzati E, Padovani R, Morrone B, Finizio F, Gaist G: Cerebral cavernous angiomas in children. J Neurosurg. 1980, 53 (6): 826-832. 10.3171/jns.1980.53.6.0826.CrossRefPubMed
5.
go back to reference Lavyne MH, Patterson RH: Subchoroidal trans-velum interpositum approach to mid-third ventricular tumors. Neurosurgery. 1983, 12 (1): 86-94. 10.1227/00006123-198301000-00013.CrossRefPubMed Lavyne MH, Patterson RH: Subchoroidal trans-velum interpositum approach to mid-third ventricular tumors. Neurosurgery. 1983, 12 (1): 86-94. 10.1227/00006123-198301000-00013.CrossRefPubMed
6.
go back to reference Amagasa M, Ishibashi Y, Kayama T, Suzuki J: A total removal case of cavernous angioma at the lateral wall of the third ventricle with interhemispheric trans-lamina terminalis approach. No Shinkei Geka. 1984, 12 (4): 517-522.PubMed Amagasa M, Ishibashi Y, Kayama T, Suzuki J: A total removal case of cavernous angioma at the lateral wall of the third ventricle with interhemispheric trans-lamina terminalis approach. No Shinkei Geka. 1984, 12 (4): 517-522.PubMed
7.
go back to reference Harbaugh RE, Roberts DW, Fratkin JD: Hemangioma calcificans. Case report. J Neurosurg. 1984, 60 (2): 417-419.PubMed Harbaugh RE, Roberts DW, Fratkin JD: Hemangioma calcificans. Case report. J Neurosurg. 1984, 60 (2): 417-419.PubMed
8.
go back to reference Yamasaki T, Handa H, Yamashita J, Paine JT, Tashiro Y, Uno A, Ishikawa M, Asato R: Intracranial and orbital cavernous angiomas. A review of 30 cases. J Neurosurg. 1986, 64 (2): 197-208. 10.3171/jns.1986.64.2.0197.CrossRefPubMed Yamasaki T, Handa H, Yamashita J, Paine JT, Tashiro Y, Uno A, Ishikawa M, Asato R: Intracranial and orbital cavernous angiomas. A review of 30 cases. J Neurosurg. 1986, 64 (2): 197-208. 10.3171/jns.1986.64.2.0197.CrossRefPubMed
9.
go back to reference Voci A, Panzarasa G, Formaggio G, Arrigoni M, Geuna E: Rare localizations of cavernomas. 4 personal cases. Neurochirurgie. 1989, 35 (2): 99-101.PubMed Voci A, Panzarasa G, Formaggio G, Arrigoni M, Geuna E: Rare localizations of cavernomas. 4 personal cases. Neurochirurgie. 1989, 35 (2): 99-101.PubMed
10.
go back to reference Ogawa A, Katakura R, Yoshimoto T: Third ventricle cavernous angioma: report of two cases. Surg Neurol. 1990, 34 (6): 414-420. 10.1016/0090-3019(90)90246-L.CrossRefPubMed Ogawa A, Katakura R, Yoshimoto T: Third ventricle cavernous angioma: report of two cases. Surg Neurol. 1990, 34 (6): 414-420. 10.1016/0090-3019(90)90246-L.CrossRefPubMed
11.
go back to reference Katayama Y, Tsubokawa T, Maeda T, Yamamoto T: Surgical management of cavernous malformations of the third ventricle. J Neurosurg. 1994, 80 (1): 64-72. 10.3171/jns.1994.80.1.0064.CrossRefPubMed Katayama Y, Tsubokawa T, Maeda T, Yamamoto T: Surgical management of cavernous malformations of the third ventricle. J Neurosurg. 1994, 80 (1): 64-72. 10.3171/jns.1994.80.1.0064.CrossRefPubMed
12.
go back to reference Sinson G, Zager EL, Grossman RI, Gennarelli TA, Flamm ES: Cavernous malformations of the third ventricle. Neurosurgery. 1995, 37 (1): 37-42. 10.1227/00006123-199507000-00005.CrossRefPubMed Sinson G, Zager EL, Grossman RI, Gennarelli TA, Flamm ES: Cavernous malformations of the third ventricle. Neurosurgery. 1995, 37 (1): 37-42. 10.1227/00006123-199507000-00005.CrossRefPubMed
13.
go back to reference Reyns N, Assaker R, Louis E, Lejeune JP: Intraventricular cavernomas: three cases and review of the literature. Neurosurgery. 1999, 44 (3): 648-654. 10.1097/00006123-199903000-00119. Discussion 654–645CrossRefPubMed Reyns N, Assaker R, Louis E, Lejeune JP: Intraventricular cavernomas: three cases and review of the literature. Neurosurgery. 1999, 44 (3): 648-654. 10.1097/00006123-199903000-00119. Discussion 654–645CrossRefPubMed
14.
go back to reference Crivelli G, Dario A, Cerati M, Dorizzi A: Third ventricle cavernoma associated with venous angioma. Case report and review of the literature. J Neurosurg Sci. 2002, 46 (3–4): 127-130.PubMed Crivelli G, Dario A, Cerati M, Dorizzi A: Third ventricle cavernoma associated with venous angioma. Case report and review of the literature. J Neurosurg Sci. 2002, 46 (3–4): 127-130.PubMed
15.
go back to reference Wang CH, Lin SM, Chen Y, Tseng SH: Multiple deep-seated cavernomas in the third ventricle, hypothalamus and thalamus. Acta Neurochir (Wien). 2003, 145 (6): 505-508. Discussion 508 Wang CH, Lin SM, Chen Y, Tseng SH: Multiple deep-seated cavernomas in the third ventricle, hypothalamus and thalamus. Acta Neurochir (Wien). 2003, 145 (6): 505-508. Discussion 508
16.
go back to reference Milenkovic Z: Postural intermittent headaches as the initial symptom of a cavernoma in the third ventricle. Acta Neurochir (Wien). 2005, 147 (1): 105-106. 10.1007/s00701-004-0393-2.CrossRef Milenkovic Z: Postural intermittent headaches as the initial symptom of a cavernoma in the third ventricle. Acta Neurochir (Wien). 2005, 147 (1): 105-106. 10.1007/s00701-004-0393-2.CrossRef
17.
go back to reference Darwish B, Boet R, Finnis N, Smith N: Third ventricular cavernous haemangioma. J Clin Neurosci. 2005, 12 (5): 601-603. 10.1016/j.jocn.2004.08.025.CrossRefPubMed Darwish B, Boet R, Finnis N, Smith N: Third ventricular cavernous haemangioma. J Clin Neurosci. 2005, 12 (5): 601-603. 10.1016/j.jocn.2004.08.025.CrossRefPubMed
18.
go back to reference Longatti P, Fiorindi A, Perin A, Baratto V, Martinuzzi A: Cavernoma of the foramen of Monro. Case report and review of the literature. Neurosurg Focus. 2006, 21 (1): e13-PubMed Longatti P, Fiorindi A, Perin A, Baratto V, Martinuzzi A: Cavernoma of the foramen of Monro. Case report and review of the literature. Neurosurg Focus. 2006, 21 (1): e13-PubMed
19.
go back to reference Zakaria MA, Abdullah JM, George JP, Mutum SS, Lee NN: Third ventricular cavernous angioma. Med J Malaysia. 2006, 61 (2): 229-232.PubMed Zakaria MA, Abdullah JM, George JP, Mutum SS, Lee NN: Third ventricular cavernous angioma. Med J Malaysia. 2006, 61 (2): 229-232.PubMed
20.
go back to reference Kivelev J, Laakso A, Niemela M, Hernesniemi J: Advances in the biology of cerebral cavernous malformations. Surg Neurol Int. 2010, 1: 61-10.4103/2152-7806.70955.PubMedCentralCrossRefPubMed Kivelev J, Laakso A, Niemela M, Hernesniemi J: Advances in the biology of cerebral cavernous malformations. Surg Neurol Int. 2010, 1: 61-10.4103/2152-7806.70955.PubMedCentralCrossRefPubMed
21.
go back to reference Chadduck WM, Binet EF, Farrell FW, Araoz CA, Reding DL: Intraventricular cavernous hemangioma: report of three cases and review of the literature. Neurosurgery. 1985, 16 (2): 189-197. 10.1227/00006123-198502000-00011.CrossRefPubMed Chadduck WM, Binet EF, Farrell FW, Araoz CA, Reding DL: Intraventricular cavernous hemangioma: report of three cases and review of the literature. Neurosurgery. 1985, 16 (2): 189-197. 10.1227/00006123-198502000-00011.CrossRefPubMed
22.
go back to reference Ishikawa M, Handa H, Moritake K, Mori K, Nakano Y, Aii H: Computed tomography of cerebral cavernous hemangiomas. J Comput Assist Tomogr. 1980, 4 (5): 587-591. 10.1097/00004728-198010000-00002.CrossRefPubMed Ishikawa M, Handa H, Moritake K, Mori K, Nakano Y, Aii H: Computed tomography of cerebral cavernous hemangiomas. J Comput Assist Tomogr. 1980, 4 (5): 587-591. 10.1097/00004728-198010000-00002.CrossRefPubMed
23.
go back to reference Sigal R, Halimi P, Doyon D, Blas C, Chan KY: Imaging of cavernomas of the brain. Tomodensitometry and magnetic resonance imaging. Neurochirurgie. 1989, 35 (2): 89-94.PubMed Sigal R, Halimi P, Doyon D, Blas C, Chan KY: Imaging of cavernomas of the brain. Tomodensitometry and magnetic resonance imaging. Neurochirurgie. 1989, 35 (2): 89-94.PubMed
24.
go back to reference Mai JC, Ramanathan D, Kim LJ, Sekhar LN: Surgical resection of cavernous malformations of the brainstem: evolution of a minimally invasive technique. World Neurosurg. 2013, 79 (5–6): 691-703.CrossRefPubMed Mai JC, Ramanathan D, Kim LJ, Sekhar LN: Surgical resection of cavernous malformations of the brainstem: evolution of a minimally invasive technique. World Neurosurg. 2013, 79 (5–6): 691-703.CrossRefPubMed
25.
go back to reference Deshmukh VR, Albuquerque FC, Zabramski JM, Spetzler RF: Surgical management of cavernous malformations involving the cranial nerves. Neurosurgery. 2003, 53 (2): 352-357. 10.1227/01.NEU.0000073531.84342.C2. Discussion 357CrossRefPubMed Deshmukh VR, Albuquerque FC, Zabramski JM, Spetzler RF: Surgical management of cavernous malformations involving the cranial nerves. Neurosurgery. 2003, 53 (2): 352-357. 10.1227/01.NEU.0000073531.84342.C2. Discussion 357CrossRefPubMed
26.
go back to reference Ziyal IM, Sekhar LN, Salas E, Sen C: Surgical management of cavernous malformations of the brain stem. Br J Neurosurg. 1999, 13 (4): 366-375. 10.1080/02688699943466.CrossRefPubMed Ziyal IM, Sekhar LN, Salas E, Sen C: Surgical management of cavernous malformations of the brain stem. Br J Neurosurg. 1999, 13 (4): 366-375. 10.1080/02688699943466.CrossRefPubMed
Metadata
Title
Cavernous hemangioma of the third ventricle: a case report and review of the literature
Authors
Moon-Soo Han
Kyung-Sub Moon
Kyung-Hwa Lee
Seul-Kee Kim
Shin Jung
Publication date
01-12-2014
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-12-237

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