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Published in: Clinical Rheumatology 9/2019

01-09-2019 | Care | Original Article

Prevalence of chondrocalcinosis in a Mexican tertiary care institution of musculoskeletal disorders

Authors: Paloma De la Garza-Montaño, Carlos Pineda, Carlos Alberto Lozada-Pérez, Katia Camargo-Ibarias, María Fernanda González-Hernández, Alberto Avila-Luna, Gerardo A. Ruiz-De la Garza, Chiara Bertolazzi, Denise Clavijo-Cornejo, Marwin Gutierrez

Published in: Clinical Rheumatology | Issue 9/2019

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Abstract

Introduction/objectives

The prevalence of chondrocalcinosis (CC) was reported as variable according to the geographic populations. However, there are no data regarding its prevalence in Mexico. Thus, we decided to investigate the Mexican prevalence of CC in a cohort of patients from a tertiary health care institution.

Methods

A retrospective analysis of radiographs of knees and wrists from our institution was performed. Inclusion criteria included patients > 50 years old having radiographs of knees and wrists. Radiographic presence of CC was classified according to a dichotomous evaluation assayed by two rheumatologists experts on the area.

Results

A total of 3.350 radiographs from 1.602 patients were evaluated. Forty-seven patients showed calcifications in at least one knee or wrist for an overall prevalence of 3%, of which 23.4% were men and 76.6% women. The knee was more commonly affected than the wrist (85.1% and 14.9% respectively). The prevalence according to gender was 2.9% in women, whereas, it was 3.2% in men. Only two patients (4.3%) showed a contemporaneous presence of CC in both hands and both knees. At knee level, the prevalence was 2.7%, whereas at the wrist, we reported a prevalence of 4.9%.

Conclusions

The prevalence of CC for Mexican population had not been reported so far. This a starting point to break the silence and encourage the knowledge of how this disease is associated with possible risk factors in Mexican population.
Key Points
The prevalence of chondrocalcinosis in Mexico was 3%.
The prevalence of knee chondrocalcinosis increases according to the age in women’s.
The nixtamalized meals could be a protective factor for CC in Mexican population.
Literature
1.
go back to reference Zhang W, Doherty M, Bardin T, Barskova V, Guerne PA, Jansen TL, Leeb BF, Perez-Ruiz F, Pimentao J, Punzi L (2011) European league against rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 70:563–7501CrossRefPubMed Zhang W, Doherty M, Bardin T, Barskova V, Guerne PA, Jansen TL, Leeb BF, Perez-Ruiz F, Pimentao J, Punzi L (2011) European league against rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 70:563–7501CrossRefPubMed
2.
go back to reference Gutierrez M, Di Geso L, Salaffi F, Carotti M, Girolimetti R, De Angelis R, Filippucci E, Grassi W (2014) Ultrasound detection of cartilage calcification at knee level in calcium pyrophosphate deposition disease. Arthritis Care Res 66:69–73CrossRef Gutierrez M, Di Geso L, Salaffi F, Carotti M, Girolimetti R, De Angelis R, Filippucci E, Grassi W (2014) Ultrasound detection of cartilage calcification at knee level in calcium pyrophosphate deposition disease. Arthritis Care Res 66:69–73CrossRef
3.
go back to reference Richette P, Bardin T, Doherty M (2009) An update on the epidemiology of calcium pyrophosphate dihydrate crystal deposition disease. Rheumatology (Oxford) 48:711–715CrossRef Richette P, Bardin T, Doherty M (2009) An update on the epidemiology of calcium pyrophosphate dihydrate crystal deposition disease. Rheumatology (Oxford) 48:711–715CrossRef
4.
go back to reference Neame RL, Carr AJ, Muir K, Doherty M (2003) UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte. Ann Rheum Dis 62:513–518CrossRefPubMedPubMedCentral Neame RL, Carr AJ, Muir K, Doherty M (2003) UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte. Ann Rheum Dis 62:513–518CrossRefPubMedPubMedCentral
5.
go back to reference Resnick D, Niwayama G, Goergen TG, Utsinger PD, Shapiro RF, Haselwood DH, Wiesner KB (1977) Clinical, radiographic and pathologic abnormalities in calcium pyrophosphate dihydrate deposition disease (CPPD): pseudogout. Radiology 122:1–15CrossRefPubMed Resnick D, Niwayama G, Goergen TG, Utsinger PD, Shapiro RF, Haselwood DH, Wiesner KB (1977) Clinical, radiographic and pathologic abnormalities in calcium pyrophosphate dihydrate deposition disease (CPPD): pseudogout. Radiology 122:1–15CrossRefPubMed
6.
go back to reference Doherty M, Dieppe P (1988) Clinical aspects of calcium pyrophosphate dihydrate crystal deposition. Rheum Dis Clin N Am 14:395–414 Doherty M, Dieppe P (1988) Clinical aspects of calcium pyrophosphate dihydrate crystal deposition. Rheum Dis Clin N Am 14:395–414
7.
go back to reference McCarty DJ (1993) Calcium pyrophosphate dihydrate crystal deposition disease. In: Schumacher HR Jr (ed) Primer on the rheumatic diseases, 10th edn. Arthritis Foundation, Atlanta, pp 219–222 McCarty DJ (1993) Calcium pyrophosphate dihydrate crystal deposition disease. In: Schumacher HR Jr (ed) Primer on the rheumatic diseases, 10th edn. Arthritis Foundation, Atlanta, pp 219–222
8.
go back to reference McCarty DJ Jr, Haskin ME (1963) The roentgenographic aspects of pseudogout (articular chondrocalcinosis): an analysis of 20 cases. Am J Roentgenol Radium Therapy, Nucl Med 90:1248–1257 McCarty DJ Jr, Haskin ME (1963) The roentgenographic aspects of pseudogout (articular chondrocalcinosis): an analysis of 20 cases. Am J Roentgenol Radium Therapy, Nucl Med 90:1248–1257
9.
go back to reference Phelps P, Steele AD, McCarty DJ Jr (1968) Compensated polarized light microscopy. Identification of crystals in synovial fluids from gout and pseudogout. JAMA 203:508–512CrossRefPubMed Phelps P, Steele AD, McCarty DJ Jr (1968) Compensated polarized light microscopy. Identification of crystals in synovial fluids from gout and pseudogout. JAMA 203:508–512CrossRefPubMed
10.
go back to reference Felson DT, Anderson JJ, Naimark A, Kannel W, Meenan RF (1989) The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham study. J Rheumatol 16:1241–1245PubMed Felson DT, Anderson JJ, Naimark A, Kannel W, Meenan RF (1989) The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham study. J Rheumatol 16:1241–1245PubMed
11.
go back to reference Sanmartí R, Pañella D, Brancós MA, Canela J, Collado A, Brugués J (1993) Prevalence of articular chondrocalcinosis in elderly subjects in a rural area of Catalonia. Ann Rheum Dis 52:418–422CrossRefPubMedPubMedCentral Sanmartí R, Pañella D, Brancós MA, Canela J, Collado A, Brugués J (1993) Prevalence of articular chondrocalcinosis in elderly subjects in a rural area of Catalonia. Ann Rheum Dis 52:418–422CrossRefPubMedPubMedCentral
12.
go back to reference Harris ED Jr (2001) Clinical features of rheumatoid arthritis. In: Ruddy S, Harris ED Jr, Sledge CB (eds) Kelley’s textbook of rheumatology, 6th edn. Saunders, Philadelphia, pp 967–1000 Harris ED Jr (2001) Clinical features of rheumatoid arthritis. In: Ruddy S, Harris ED Jr, Sledge CB (eds) Kelley’s textbook of rheumatology, 6th edn. Saunders, Philadelphia, pp 967–1000
13.
go back to reference Zhang Y, Terkeltaub R, Nevitt M, Xu L, Neogi T, Aliabadi P, Niu J, Felson DT (2006) Lower prevalence of chondrocalcinosis in Chinese subjects in Beijing than in white subjects in the United States: the Beijing osteoarthritis study. Arthritis Rheum 54:3508–3512CrossRefPubMed Zhang Y, Terkeltaub R, Nevitt M, Xu L, Neogi T, Aliabadi P, Niu J, Felson DT (2006) Lower prevalence of chondrocalcinosis in Chinese subjects in Beijing than in white subjects in the United States: the Beijing osteoarthritis study. Arthritis Rheum 54:3508–3512CrossRefPubMed
14.
go back to reference Ramonda R, Musacchio E, Perissinotto E, Sartori L, Punzi L, Corti MC, Hirsch R, Manzato E, Zambon S, Baggio G, Crepaldi G (2009) Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. (PROgetto Veneto Anziani) study. Clin Exp Rheumatol 27:981–984PubMed Ramonda R, Musacchio E, Perissinotto E, Sartori L, Punzi L, Corti MC, Hirsch R, Manzato E, Zambon S, Baggio G, Crepaldi G (2009) Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. (PROgetto Veneto Anziani) study. Clin Exp Rheumatol 27:981–984PubMed
15.
go back to reference Dodds WJ, Steinbach HL (1968) Primary hyperparathyroidism and articular cartilage calcification. Am J Roentgenol Radium Therapy, Nucl Med 104:884–892CrossRef Dodds WJ, Steinbach HL (1968) Primary hyperparathyroidism and articular cartilage calcification. Am J Roentgenol Radium Therapy, Nucl Med 104:884–892CrossRef
17.
go back to reference Tfelt-Hansen J, Brown EM (2005) The calcium-sensing receptor in normal physiology and pathophysiology: a review. Crit Rev Clin Lab Sci 42:35–70CrossRefPubMed Tfelt-Hansen J, Brown EM (2005) The calcium-sensing receptor in normal physiology and pathophysiology: a review. Crit Rev Clin Lab Sci 42:35–70CrossRefPubMed
18.
19.
go back to reference Bressani R, Turcios JC, Colmenares de Ruiz AS, de Palomo PP (2004) Effect of processing conditions on phytic acid, calcium, iron, and zinc contents of lime- cooked maize. J Agric Food Chem 52:1157–1162CrossRefPubMed Bressani R, Turcios JC, Colmenares de Ruiz AS, de Palomo PP (2004) Effect of processing conditions on phytic acid, calcium, iron, and zinc contents of lime- cooked maize. J Agric Food Chem 52:1157–1162CrossRefPubMed
20.
go back to reference Toesca A, Pagnotta A, Zumbo A, Sadun R (2008) Estrogen and progesterone receptors in carpal tunnel syndrome. Cell Biol Int 32(1):75–79CrossRefPubMed Toesca A, Pagnotta A, Zumbo A, Sadun R (2008) Estrogen and progesterone receptors in carpal tunnel syndrome. Cell Biol Int 32(1):75–79CrossRefPubMed
21.
go back to reference Martín-Millán M, Castañeda S (2013) Estrogens, osteoarthritis and inflammation. Joint Bone Spine 80:368–373CrossRefPubMed Martín-Millán M, Castañeda S (2013) Estrogens, osteoarthritis and inflammation. Joint Bone Spine 80:368–373CrossRefPubMed
22.
go back to reference Ushiyama T, Inoue K, Nishioka J (1995) Expression of estrogen receptor related protein (p29) and estradiol binding in human arthritic synovium. J Rheumatol 22:421–426PubMed Ushiyama T, Inoue K, Nishioka J (1995) Expression of estrogen receptor related protein (p29) and estradiol binding in human arthritic synovium. J Rheumatol 22:421–426PubMed
23.
go back to reference Tsai CL, Liu TK (1993) Estradiol-induced knee osteoarthrosis in ovariectomized rabbits. Clin Orthop (291):295–302 Tsai CL, Liu TK (1993) Estradiol-induced knee osteoarthrosis in ovariectomized rabbits. Clin Orthop (291):295–302
24.
go back to reference Abhishek A, Doherty S, Maciewicz R, Muir K, Zhang W, Doherty M (2012) Chondrocalcinosis is common in the absence of knee involvement. Arthritis Res Ther 14:R205CrossRefPubMedPubMedCentral Abhishek A, Doherty S, Maciewicz R, Muir K, Zhang W, Doherty M (2012) Chondrocalcinosis is common in the absence of knee involvement. Arthritis Res Ther 14:R205CrossRefPubMedPubMedCentral
25.
go back to reference Canhão H, Fonseca JE, Leandro MJ, Romeu JC, Pimentão JB, Costa JT, Queiroz MV (2001) Cross-sectional study of 50 patients with calcium pyrophosphate dihydrate crystal arthropathy. Clin Rheumatol 20:119–122CrossRefPubMed Canhão H, Fonseca JE, Leandro MJ, Romeu JC, Pimentão JB, Costa JT, Queiroz MV (2001) Cross-sectional study of 50 patients with calcium pyrophosphate dihydrate crystal arthropathy. Clin Rheumatol 20:119–122CrossRefPubMed
26.
go back to reference Engdahl C, Börjesson AE, Forsman HF, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H, Lagerquist MK (2014) The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis. Arthritis Res Ther 16:R150CrossRefPubMedPubMedCentral Engdahl C, Börjesson AE, Forsman HF, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H, Lagerquist MK (2014) The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis. Arthritis Res Ther 16:R150CrossRefPubMedPubMedCentral
27.
go back to reference Wang W, Hayami T, Kapila S (2009) Female hormone receptors are differentially expressed in mouse fibrocartilages. Osteoarthr Cartil 17:646–654CrossRefPubMed Wang W, Hayami T, Kapila S (2009) Female hormone receptors are differentially expressed in mouse fibrocartilages. Osteoarthr Cartil 17:646–654CrossRefPubMed
Metadata
Title
Prevalence of chondrocalcinosis in a Mexican tertiary care institution of musculoskeletal disorders
Authors
Paloma De la Garza-Montaño
Carlos Pineda
Carlos Alberto Lozada-Pérez
Katia Camargo-Ibarias
María Fernanda González-Hernández
Alberto Avila-Luna
Gerardo A. Ruiz-De la Garza
Chiara Bertolazzi
Denise Clavijo-Cornejo
Marwin Gutierrez
Publication date
01-09-2019
Publisher
Springer London
Keyword
Care
Published in
Clinical Rheumatology / Issue 9/2019
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-019-04614-1

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