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Antimicrobial Resistance & Infection Control
Published in: Antimicrobial Resistance & Infection Control 1/2020

01-12-2020 | Care | Research

Prevalence and molecular characterizations of Staphylococcus aureus nasal colonization among patients in pediatric intensive care units in Taiwan

Authors: Yu-Hsin Chen, Kuan-Ying A. Huang, Yi-Chuan Huang, Hsin Chi, Chun-Yi Lu, Luan-Yin Chang, Yu-Huai Ho, Chia-Yu Chi, Ching-Chuan Liu, Li-Min Huang, Tien Yu Owen Yang, Yhu-Chering Huang

Published in: Antimicrobial Resistance & Infection Control | Issue 1/2020

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Abstract

Background

Nasal colonization of Staphylococcus aureus is a risk factor for the pathogen transmission and the development of infections. Limited information is available on the prevalence and molecular characteristics of S. aureus colonization in pediatric intensive care unit (ICU) patients.

Methods

A cross-sectional, island-wide study was conducted in 2011. Nasal swabs were collected from pediatric ICU patients at six tertiary hospitals in Taiwan.

Results

Of 114 patients enrolled in total, nasal colonization of S. arueus was detected in 30 (26.3%) of them, among whom 20 (17.5%) with methicillin-resistant S. arueus (MRSA). The ST59/SCCmec IV and V clones were most common and accounted for 45% of MRSA isolates, followed by ST239/SCCmec III (25%) and ST45/SCCmec IV (20%) clones. Three ST59 MRSA isolates carried the Panton-Valentine Leukocidin genes.

Conclusions

The results indicated a high prevalence of S. arueus and MRSA nasal colonization among pediatric ICU patients in Taiwan. Identification of epidemic clones warrants the implement of infection control measures to reduce colonization and prevent the dissemination of MRSA in hospitals.
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Metadata
Title
Prevalence and molecular characterizations of Staphylococcus aureus nasal colonization among patients in pediatric intensive care units in Taiwan
Authors
Yu-Hsin Chen
Kuan-Ying A. Huang
Yi-Chuan Huang
Hsin Chi
Chun-Yi Lu
Luan-Yin Chang
Yu-Huai Ho
Chia-Yu Chi
Ching-Chuan Liu
Li-Min Huang
Tien Yu Owen Yang
Yhu-Chering Huang
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Antimicrobial Resistance & Infection Control / Issue 1/2020
Electronic ISSN: 2047-2994
DOI
https://doi.org/10.1186/s13756-020-0700-6

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