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Published in: BMC Public Health 1/2022

Open Access 01-12-2022 | Care | Research

Implementing a multisector public-private partnership to improve urban hypertension management in low-and middle- income countries

Authors: Johannes Boch, Lakshmi Venkitachalam, Adela Santana, Olivia Jones, Theresa Reiker, Sarah Des Rosiers, Jason T. Shellaby, Jasmina Saric, Peter Steinmann, Jose M. E. Ferrer, Louise Morgan, Asha Barshilia, Edmir Peralta Rollemberg Albuquerque, Alvaro Avezum, Joseph Barboza, Yara C. Baxter, Luiz Bortolotto, Enkhtuya Byambasuren, Márcia Cerqueira, Naranjargal Dashdorj, Karina Mauro Dib, Babacar Guèye, Karim Seck, Mariana Silveira, Suely Miya Shiraishi Rollemberg, Renato W. de Oliveira, Tumurbaatar Luvsansambuu, Ann Aerts

Published in: BMC Public Health | Issue 1/2022

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Abstract

Background

Cardiovascular disease presents an increasing health burden to low- and middle-income countries. Although ample therapeutic options and care improvement frameworks exist to address its prime risk factor, hypertension, blood pressure control rates remain poor. We describe the results of an effectiveness study of a multisector urban population health initiative that targets hypertension in a real-world implementation setting in cities across three continents. The initiative followed the “CARDIO4Cities” approach (quality of Care, early Access, policy Reform, Data and digital technology, Intersectoral collaboration, and local Ownership).

Method

The approach was applied in Ulaanbaatar in Mongolia, Dakar in Senegal, and São Paulo in Brazil. In each city, a portfolio of evidence-based practices was implemented, tailored to local priorities and available data. Outcomes were measured by extracting hypertension diagnosis, treatment and control rates from primary health records. Data from 18,997 patients with hypertension in primary health facilities were analyzed.

Results

Over one to two years of implementation, blood pressure control rates among enrolled patients receiving medication tripled in São Paulo (from 12·3% to 31·2%) and Dakar (from 6·7% to 19·4%) and increased six-fold in Ulaanbaatar (from 3·1% to 19·7%).

Conclusions

This study provides first evidence that a multisectoral population health approach to implement known best-practices, supported by data and digital technologies, and relying on local buy-in and ownership, can improve hypertension control in high-burden urban primary care settings in low-and middle-income countries.
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Literature
1.
go back to reference Stanaway JD, Afshin A, Gakidou E, Lim SS, Abate D, Abate KH, et al. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2018;392(10159):1923–94.CrossRef Stanaway JD, Afshin A, Gakidou E, Lim SS, Abate D, Abate KH, et al. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2018;392(10159):1923–94.CrossRef
2.
go back to reference Mills K, Bundy J, Kelly T, Reed J, Kearney P, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016;134(6):441–50.CrossRef Mills K, Bundy J, Kelly T, Reed J, Kearney P, Reynolds K, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016;134(6):441–50.CrossRef
3.
go back to reference Whelton PK, Carey RM, Aronow WS, Casey DE, Collins KJ, Dennison Himmelfarb C, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. J Am Coll Cardiol. 2018;71(19):e127–248.CrossRef Whelton PK, Carey RM, Aronow WS, Casey DE, Collins KJ, Dennison Himmelfarb C, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. J Am Coll Cardiol. 2018;71(19):e127–248.CrossRef
4.
go back to reference Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). Eur Heart J. 2018;39(33):3021–104.CrossRef Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). Eur Heart J. 2018;39(33):3021–104.CrossRef
5.
go back to reference Adler AJ, Prabhakaran D, Bovet P, Kazi DS, Mancia G, Mungal-Singh V, et al. Reducing cardiovascular mortality through prevention and management of raised blood pressure. Glob Heart. 2015;10(2):111–22.CrossRef Adler AJ, Prabhakaran D, Bovet P, Kazi DS, Mancia G, Mungal-Singh V, et al. Reducing cardiovascular mortality through prevention and management of raised blood pressure. Glob Heart. 2015;10(2):111–22.CrossRef
6.
go back to reference Egan BM, Sutherland SE, Rakotz M, Yang J, Hanlin RB, Davis RA, et al. Improving hypertension control in primary care with the measure accurately, act rapidly, and partner with patients protocol: results at 6 and 12 months. Hypertension. 2018;72(6):1320–7.CrossRef Egan BM, Sutherland SE, Rakotz M, Yang J, Hanlin RB, Davis RA, et al. Improving hypertension control in primary care with the measure accurately, act rapidly, and partner with patients protocol: results at 6 and 12 months. Hypertension. 2018;72(6):1320–7.CrossRef
7.
go back to reference Yusuf S, Wood D, Ralston J, Reddy KS. The world heart Federation's vision for worldwide cardiovascular disease prevention. Lancet. 2015;386(9991):399–402.CrossRef Yusuf S, Wood D, Ralston J, Reddy KS. The world heart Federation's vision for worldwide cardiovascular disease prevention. Lancet. 2015;386(9991):399–402.CrossRef
8.
go back to reference Chow CK, Teo KK, Rangarajan S, Islam S, Gupta R, Avezum A, et al. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries. JAMA. 2013;310(9):959–68.CrossRef Chow CK, Teo KK, Rangarajan S, Islam S, Gupta R, Avezum A, et al. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries. JAMA. 2013;310(9):959–68.CrossRef
9.
go back to reference Yusuf S, Rangarajan S, Teo K, Islam S, Li W, Liu L, et al. Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med. 2014;371(9):818–27.CrossRef Yusuf S, Rangarajan S, Teo K, Islam S, Li W, Liu L, et al. Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med. 2014;371(9):818–27.CrossRef
10.
go back to reference Geldsetzer P, Manne-Goehler J, Marcus M-E, Ebert C, Zhumadilov Z, Wesseh CS, et al. The state of hypertension care in 44 low-income and middle-income countries: a cross-sectional study of nationally representative individual-level data from 1· 1 million adults. Lancet. 2019;394(10199):652–62.CrossRef Geldsetzer P, Manne-Goehler J, Marcus M-E, Ebert C, Zhumadilov Z, Wesseh CS, et al. The state of hypertension care in 44 low-income and middle-income countries: a cross-sectional study of nationally representative individual-level data from 1· 1 million adults. Lancet. 2019;394(10199):652–62.CrossRef
11.
go back to reference Zhou B, Carrillo-Larco RM, Danaei G, Riley LM, Paciorek CJ, Stevens GA, et al. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021;398(10304):957–80.CrossRef Zhou B, Carrillo-Larco RM, Danaei G, Riley LM, Paciorek CJ, Stevens GA, et al. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021;398(10304):957–80.CrossRef
12.
go back to reference Gupta R, Yusuf S. Challenges in management and prevention of ischemic heart disease in low socioeconomic status people in LLMICs. BMC Med. 2019;17(1):1–11.CrossRef Gupta R, Yusuf S. Challenges in management and prevention of ischemic heart disease in low socioeconomic status people in LLMICs. BMC Med. 2019;17(1):1–11.CrossRef
13.
go back to reference Kushitor MK, Boatemaa S. The double burden of disease and the challenge of health access: evidence from access, bottlenecks, cost and equity facility survey in Ghana. Plos one. 2018;13(3):e0194677.CrossRef Kushitor MK, Boatemaa S. The double burden of disease and the challenge of health access: evidence from access, bottlenecks, cost and equity facility survey in Ghana. Plos one. 2018;13(3):e0194677.CrossRef
14.
go back to reference Elsey H, Agyepong I, Huque R, Quayyem Z, Baral S, Ebenso B, et al. Rethinking health systems in the context of urbanisation: challenges from four rapidly urbanising low-income and middle-income countries. BMJ Glob Health. 2019;4(3):e001501.CrossRef Elsey H, Agyepong I, Huque R, Quayyem Z, Baral S, Ebenso B, et al. Rethinking health systems in the context of urbanisation: challenges from four rapidly urbanising low-income and middle-income countries. BMJ Glob Health. 2019;4(3):e001501.CrossRef
15.
go back to reference Mozheyko M, Eregin S, Danilenko N, Vigdorchik A, Tobe SW, Campbell N, et al. Hypertension in Russia: changes observed after 4 years of a comprehensive health system improvement program in the Yaroslavl region. J Clin Hypertens. 2017;19(2):198–204.CrossRef Mozheyko M, Eregin S, Danilenko N, Vigdorchik A, Tobe SW, Campbell N, et al. Hypertension in Russia: changes observed after 4 years of a comprehensive health system improvement program in the Yaroslavl region. J Clin Hypertens. 2017;19(2):198–204.CrossRef
16.
go back to reference Piot P, Aerts A, Wood DA, Lamptey P, Oti S, Connell K, et al. Innovating healthcare delivery to address noncommunicable diseases in low-income settings: the example of hypertension. Futur Cardiol. 2016;12:401–3.CrossRef Piot P, Aerts A, Wood DA, Lamptey P, Oti S, Connell K, et al. Innovating healthcare delivery to address noncommunicable diseases in low-income settings: the example of hypertension. Futur Cardiol. 2016;12:401–3.CrossRef
18.
go back to reference Myanganbayar M, Baatarsuren U, Chen G, Campbell NR, Bosurgi R, So G, et al. Hypertension knowledge, attitudes, and practices of nurses and physicians in primary care in Ulaanbaatar Mongolia. J Clin Hypertens (Greenwich). 2019;21(8):1202–9.CrossRef Myanganbayar M, Baatarsuren U, Chen G, Campbell NR, Bosurgi R, So G, et al. Hypertension knowledge, attitudes, and practices of nurses and physicians in primary care in Ulaanbaatar Mongolia. J Clin Hypertens (Greenwich). 2019;21(8):1202–9.CrossRef
19.
go back to reference Potts H, Baatarsuren U, Myanganbayar M, Purevdorj B, Lkhagvadorj BU, Ganbat N, et al. Hypertension prevalence and control in Ulaanbaatar, Mongolia. J Clin Hypertens (Greenwich). 2020;22(1):103–10.CrossRef Potts H, Baatarsuren U, Myanganbayar M, Purevdorj B, Lkhagvadorj BU, Ganbat N, et al. Hypertension prevalence and control in Ulaanbaatar, Mongolia. J Clin Hypertens (Greenwich). 2020;22(1):103–10.CrossRef
20.
go back to reference Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, et al. Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. J Am Coll Cardiol. 2017;71(19):e127–248.CrossRef Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, et al. Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. J Am Coll Cardiol. 2017;71(19):e127–248.CrossRef
21.
go back to reference World Health Organization: HEARTS: technical package for cardiovascular disease management in primary health care. Geneva: World Health Organization; 2020. World Health Organization: HEARTS: technical package for cardiovascular disease management in primary health care. Geneva: World Health Organization; 2020.
22.
go back to reference Jeemon P, Séverin T, Amodeo C, Balabanova D, Campbell NRC, Gaita D, et al. World heart federation roadmap for hypertension – a 2021 update. Global Heart. 2021;16(1):63. Jeemon P, Séverin T, Amodeo C, Balabanova D, Campbell NRC, Gaita D, et al. World heart federation roadmap for hypertension – a 2021 update. Global Heart. 2021;16(1):63.
23.
go back to reference Malachias M, Gomes M, Nobre F, Alessi A, Feitosa A, Coelho E. 7th Brazilian guideline of arterial hypertension: chapter 2-diagnosis and classification. Arq Bras Cardiol. 2016;107:1–83. Malachias M, Gomes M, Nobre F, Alessi A, Feitosa A, Coelho E. 7th Brazilian guideline of arterial hypertension: chapter 2-diagnosis and classification. Arq Bras Cardiol. 2016;107:1–83.
24.
go back to reference Ndione I, Aerts A, Barshilia A, Boch J, Des Rosiers S, Ferrer JM, et al. Fostering cardiovascular health at work–case study from Senegal. BMC Public Health. 2021;21(1):1–11.CrossRef Ndione I, Aerts A, Barshilia A, Boch J, Des Rosiers S, Ferrer JM, et al. Fostering cardiovascular health at work–case study from Senegal. BMC Public Health. 2021;21(1):1–11.CrossRef
25.
go back to reference Harrell FE. Regression modeling strategies: with applications to linear models, logistic and ordinal regression, and survival analysis, vol. 3. Cham: Springer International Publishing; 2015. Harrell FE. Regression modeling strategies: with applications to linear models, logistic and ordinal regression, and survival analysis, vol. 3. Cham: Springer International Publishing; 2015.
27.
go back to reference Paim J, Travassos C, Almeida C, Bahia L, Macinko J. The Brazilian health system: history, advances, and challenges. Lancet. 2011;377(9779):1778–97.CrossRef Paim J, Travassos C, Almeida C, Bahia L, Macinko J. The Brazilian health system: history, advances, and challenges. Lancet. 2011;377(9779):1778–97.CrossRef
28.
go back to reference Secretaria Municipal da Saúde – Prefeitura de São Paulo: Cuidando de Todos: DCNT - Doenças Crônicas Não Transmissíveis na Atenção Primária à Saúde no MSP: Protocolo de Linha de Cuidados das Doenças Crônicas Não Transmissíveis (DCNT) na Atenção Primária à Saúde (APS) do Município de São Paulo. 1 edn. Instituto Tellus: São Paulo; 2020. Secretaria Municipal da Saúde – Prefeitura de São Paulo: Cuidando de Todos: DCNT - Doenças Crônicas Não Transmissíveis na Atenção Primária à Saúde no MSP: Protocolo de Linha de Cuidados das Doenças Crônicas Não Transmissíveis (DCNT) na Atenção Primária à Saúde (APS) do Município de São Paulo. 1 edn. Instituto Tellus: São Paulo; 2020.
29.
go back to reference Secretaria Municipal da Saúde – Prefeitura de São Paulo: Cuidando de Todos : DCNT Doenças Crônicas Não Transmissíveis na Atenção Primária à Saúde (APS) - Protocolo Clínico Prático para o Tratamento de Doenças Crônicas Não Transmissíveis (DCNT) na Atenção Primária à Saúde (APS): Hipertensão Arterial e Diabetes Mellitus. 1 edn. Instituto Tellus: São Paulo; 2020. Secretaria Municipal da Saúde – Prefeitura de São Paulo: Cuidando de Todos : DCNT Doenças Crônicas Não Transmissíveis na Atenção Primária à Saúde (APS) - Protocolo Clínico Prático para o Tratamento de Doenças Crônicas Não Transmissíveis (DCNT) na Atenção Primária à Saúde (APS): Hipertensão Arterial e Diabetes Mellitus. 1 edn. Instituto Tellus: São Paulo; 2020.
30.
go back to reference Secretaria Municipal da Saúde – Prefeitura de São Paulo: Cuidando de Todos: DCNT Doenças Crônicas não transmissíveis na atenção primária à saúde: Protocolo Clínico Prático para o Tratamento de Hipertensão Arterial e Diabetes Mellitus. Instituto Tellus: São Paulo; 2020. Secretaria Municipal da Saúde – Prefeitura de São Paulo: Cuidando de Todos: DCNT Doenças Crônicas não transmissíveis na atenção primária à saúde: Protocolo Clínico Prático para o Tratamento de Hipertensão Arterial e Diabetes Mellitus. Instituto Tellus: São Paulo; 2020.
31.
go back to reference Tellus I. Manual Catinho Cuidando de Todos. In.; 2021. Tellus I. Manual Catinho Cuidando de Todos. In.; 2021.
33.
go back to reference Ministério da Saúde: Vigitel Brazil 2018: surveillance of risk and protective factors for chronic diseases by telephone survey: estimates of frequency and sociodemographic distribution of risk and protective factors for chronic diseases in the capitals of the 26 Brazilian states and the Federal District in 2018. Ministério da Saúde: Brasília; 2019. Ministério da Saúde: Vigitel Brazil 2018: surveillance of risk and protective factors for chronic diseases by telephone survey: estimates of frequency and sociodemographic distribution of risk and protective factors for chronic diseases in the capitals of the 26 Brazilian states and the Federal District in 2018. Ministério da Saúde: Brasília; 2019.
34.
go back to reference World Health Organization, Ministère de la santé et de l'Action Sociale: 2015 STEPS Country Report Senegal. Ministère de la santé et de l'Action Sociale; Dakar; 2016. World Health Organization, Ministère de la santé et de l'Action Sociale: 2015 STEPS Country Report Senegal. Ministère de la santé et de l'Action Sociale; Dakar; 2016.
35.
go back to reference World Health Organization: Third national STEPS survey on the prevalence of noncommunicable disease and injury risk Factors-2013. World Health Organization: Geneva; 2018. World Health Organization: Third national STEPS survey on the prevalence of noncommunicable disease and injury risk Factors-2013. World Health Organization: Geneva; 2018.
36.
go back to reference Rahimi K, Bidel Z, Nazarzadeh M, Copland E, Canoy D, Ramakrishnan R, et al. Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis. Lancet. 2021;397(10285):1625–36.CrossRef Rahimi K, Bidel Z, Nazarzadeh M, Copland E, Canoy D, Ramakrishnan R, et al. Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis. Lancet. 2021;397(10285):1625–36.CrossRef
37.
go back to reference Luepker RV, Steffen LM, Jacobs DR Jr, Zhou X, Blackburn H. Trends in blood pressure and hypertension detection, treatment, and control 1980 to 2009: the Minnesota heart survey. Circulation. 2012;126(15):1852–7.CrossRef Luepker RV, Steffen LM, Jacobs DR Jr, Zhou X, Blackburn H. Trends in blood pressure and hypertension detection, treatment, and control 1980 to 2009: the Minnesota heart survey. Circulation. 2012;126(15):1852–7.CrossRef
38.
go back to reference Padwal RS, Bienek A, McAlister FA, Campbell NR. Outcomes research task force of the Canadian hypertension education P: epidemiology of hypertension in Canada: an update. Can J Cardiol. 2016;32(5):687–94.CrossRef Padwal RS, Bienek A, McAlister FA, Campbell NR. Outcomes research task force of the Canadian hypertension education P: epidemiology of hypertension in Canada: an update. Can J Cardiol. 2016;32(5):687–94.CrossRef
Metadata
Title
Implementing a multisector public-private partnership to improve urban hypertension management in low-and middle- income countries
Authors
Johannes Boch
Lakshmi Venkitachalam
Adela Santana
Olivia Jones
Theresa Reiker
Sarah Des Rosiers
Jason T. Shellaby
Jasmina Saric
Peter Steinmann
Jose M. E. Ferrer
Louise Morgan
Asha Barshilia
Edmir Peralta Rollemberg Albuquerque
Alvaro Avezum
Joseph Barboza
Yara C. Baxter
Luiz Bortolotto
Enkhtuya Byambasuren
Márcia Cerqueira
Naranjargal Dashdorj
Karina Mauro Dib
Babacar Guèye
Karim Seck
Mariana Silveira
Suely Miya Shiraishi Rollemberg
Renato W. de Oliveira
Tumurbaatar Luvsansambuu
Ann Aerts
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2022
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-022-14833-y

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