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Published in: Dysphagia 1/2023

21-06-2022 | Care | Original Article

RETRACTED ARTICLE: The Characteristics and Predicators of Post-extubation Dysphagia in ICU Patients with Endotracheal Intubation

Authors: Chenyun Xia, Jianhong Ji

Published in: Dysphagia | Issue 1/2023

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Abstract

The current status and characteristics of post-extubation dysphagia in intensive care unit (ICU) patients with endotracheal intubation remain unclear, we aimed to evaluate the characteristics and identify the predicators for post-extubation dysphagia, to provide reliable reference to the clinical management and nursing care of dysphagia. Patients who underwent tracheal intubation for mechanical ventilation in the ICU of our hospital from January 1, 2020–May 31, 2021 were selected. The characteristics of patients with and without post-extubation dysphagia were analyzed. Univarinate and binary logistic regression analysis were used to screen the risk factors of dysphagia after extubation, and we established the risk prediction model according to the regression coefficients of each risk factor. 316 ICU patients with endotracheal intubation were included, the incidence of post-extubation dysphagia was 27.85%. Logistic regression analysis showed that age ≥ 65 years (OR 2.368, 95%CI 1.633 ~ 3.946), APACHE II score ≥ 15 (OR 3.727, 95%CI 3.312 ~ 4.202), length of tracheal intubation indwelling ≥ 72 h (OR 2.495, 95%CI 1.824 ~ 3.715), length of gastric tube stay ≥ 72 h (OR 1.923, 95%CI 1.452 ~ 2.882) were the risk factors of post-extubation dysphagia in ICU patients with endotracheal intubation(all p < 0.05). Six score was used as the cuff value of the model with good sensitivity and specificity. The area under the ROC curve and 95% confidence interval was 0.822 (0.746, 0.872). There are many risks of post-extubation dysphagia in ICU patients with endotracheal intubation. For high-risk patients with a score ≥ 6, early nursing care and interventions should be given as soon as possible to reduce the post-extubation dysphagia.
Literature
1.
go back to reference Fritz MA, Howell RJ, Brodsky MB, Suiter DM, Dhar SI, Rameau A, Richard T, Skelley M, Ashford JR, O’Rourke AK, et al. Moving forward with dysphagia care: implementing strategies during the COVID-19 pandemic and beyond. Dysphagia. 2021;36(2):161–9.CrossRefPubMed Fritz MA, Howell RJ, Brodsky MB, Suiter DM, Dhar SI, Rameau A, Richard T, Skelley M, Ashford JR, O’Rourke AK, et al. Moving forward with dysphagia care: implementing strategies during the COVID-19 pandemic and beyond. Dysphagia. 2021;36(2):161–9.CrossRefPubMed
2.
go back to reference Matsuo H, Yoshimura Y, Fujita S, Maeno Y. Incidence of dysphagia and its association with functional recovery and 1-year mortality in hospitalized older patients with heart failure: a prospective cohort study. J Parenter Enteral Nutr. 2021;45(2):372–80.CrossRef Matsuo H, Yoshimura Y, Fujita S, Maeno Y. Incidence of dysphagia and its association with functional recovery and 1-year mortality in hospitalized older patients with heart failure: a prospective cohort study. J Parenter Enteral Nutr. 2021;45(2):372–80.CrossRef
3.
go back to reference Miles A, Connor NP, Desai RV, Jadcherla S, Allen J, Brodsky M, Garand KL, Malandraki GA, McCulloch TM, Moss M, et al. Dysphagia care across the continuum: a multidisciplinary dysphagia research society taskforce report of service-delivery during the COVID-19 global pandemic. Dysphagia. 2021;36(2):170–82.CrossRefPubMed Miles A, Connor NP, Desai RV, Jadcherla S, Allen J, Brodsky M, Garand KL, Malandraki GA, McCulloch TM, Moss M, et al. Dysphagia care across the continuum: a multidisciplinary dysphagia research society taskforce report of service-delivery during the COVID-19 global pandemic. Dysphagia. 2021;36(2):170–82.CrossRefPubMed
4.
go back to reference McIntyre M, Doeltgen S, Dalton N, Koppa M, Chimunda T. Post-extubation dysphagia incidence in critically ill patients: a systematic review and meta-analysis. Aust Crit Care. 2021;34(1):67–75.CrossRefPubMed McIntyre M, Doeltgen S, Dalton N, Koppa M, Chimunda T. Post-extubation dysphagia incidence in critically ill patients: a systematic review and meta-analysis. Aust Crit Care. 2021;34(1):67–75.CrossRefPubMed
5.
go back to reference Zhang M, Li C, Zhang F, Han X, Yang Q, Lin T, Zhou H, Tang M, Zhou J, Shi H, et al. Prevalence of dysphagia in china: an epidemiological survey of 5943 participants. Dysphagia. 2021;36(3):339–50.CrossRefPubMed Zhang M, Li C, Zhang F, Han X, Yang Q, Lin T, Zhou H, Tang M, Zhou J, Shi H, et al. Prevalence of dysphagia in china: an epidemiological survey of 5943 participants. Dysphagia. 2021;36(3):339–50.CrossRefPubMed
6.
go back to reference Beduneau G, Souday V, Richard JC, Hamel JF, Carpentier D, Chretien JM, Bouchetemble P, Laccoureye L, Astier A, Tanguy V, et al. Persistent swallowing disorders after extubation in mechanically ventilated patients in ICU: a two-center prospective study. Ann Intensive Care. 2020;10(1):138.CrossRefPubMedPubMedCentral Beduneau G, Souday V, Richard JC, Hamel JF, Carpentier D, Chretien JM, Bouchetemble P, Laccoureye L, Astier A, Tanguy V, et al. Persistent swallowing disorders after extubation in mechanically ventilated patients in ICU: a two-center prospective study. Ann Intensive Care. 2020;10(1):138.CrossRefPubMedPubMedCentral
7.
go back to reference Dobak S, Kelly D. Tough pill to swallow: postextubation dysphagia and nutrition impact in the intensive care unit. Nutr Clin Pract. 2021;36(1):80–7.CrossRefPubMed Dobak S, Kelly D. Tough pill to swallow: postextubation dysphagia and nutrition impact in the intensive care unit. Nutr Clin Pract. 2021;36(1):80–7.CrossRefPubMed
9.
go back to reference Frajkova Z, Tedla M, Tedlova E, Suchankova M, Geneid A. Postintubation dysphagia during COVID-19 outbreak-contemporary review. Dysphagia. 2020;35(4):549–57.CrossRefPubMedPubMedCentral Frajkova Z, Tedla M, Tedlova E, Suchankova M, Geneid A. Postintubation dysphagia during COVID-19 outbreak-contemporary review. Dysphagia. 2020;35(4):549–57.CrossRefPubMedPubMedCentral
10.
go back to reference Skoretz SA, Flowers HL, Martino R. The incidence of dysphagia following endotracheal intubation: a systematic review. Chest. 2010;137(3):665–73.CrossRefPubMed Skoretz SA, Flowers HL, Martino R. The incidence of dysphagia following endotracheal intubation: a systematic review. Chest. 2010;137(3):665–73.CrossRefPubMed
12.
go back to reference Zeng L, Song Y, Dong Y, Wu Q, Zhang L, Yu L, Gao L, Shi Y. Risk score for predicting dysphagia in patients after neurosurgery: a prospective observational trial. Front Neurol. 2021;12:605687.CrossRefPubMedPubMedCentral Zeng L, Song Y, Dong Y, Wu Q, Zhang L, Yu L, Gao L, Shi Y. Risk score for predicting dysphagia in patients after neurosurgery: a prospective observational trial. Front Neurol. 2021;12:605687.CrossRefPubMedPubMedCentral
13.
go back to reference Bath PM, Lee HS, Everton LF. Swallowing therapy for dysphagia in acute and subacute stroke. Cochrane Database Syst Rev. 2018;10:CD000323.PubMed Bath PM, Lee HS, Everton LF. Swallowing therapy for dysphagia in acute and subacute stroke. Cochrane Database Syst Rev. 2018;10:CD000323.PubMed
14.
go back to reference Kim MJ, Park YH, Park YS, Song YH. Associations between prolonged intubation and developing post-extubation dysphagia and aspiration pneumonia in non-neurologic critically Ill patients. Ann Rehabil Med. 2015;39(5):763–71.CrossRefPubMedPubMedCentral Kim MJ, Park YH, Park YS, Song YH. Associations between prolonged intubation and developing post-extubation dysphagia and aspiration pneumonia in non-neurologic critically Ill patients. Ann Rehabil Med. 2015;39(5):763–71.CrossRefPubMedPubMedCentral
15.
go back to reference Xiao LJ, Guo Q, Huang FY, Liao MX, Zhang LL, Yan TB. Correlation between swallowing function and pulmonary ventilation function and respiratory muscles strength in patients with dysphagia after stroke. Zhonghua Yi Xue Za Zhi. 2020;100(7):504–8.PubMed Xiao LJ, Guo Q, Huang FY, Liao MX, Zhang LL, Yan TB. Correlation between swallowing function and pulmonary ventilation function and respiratory muscles strength in patients with dysphagia after stroke. Zhonghua Yi Xue Za Zhi. 2020;100(7):504–8.PubMed
16.
go back to reference Marvin S, Thibeault S, Ehlenbach WJ. Post-extubation dysphagia: does timing of evaluation matter? Dysphagia. 2019;34(2):210–9.CrossRefPubMed Marvin S, Thibeault S, Ehlenbach WJ. Post-extubation dysphagia: does timing of evaluation matter? Dysphagia. 2019;34(2):210–9.CrossRefPubMed
17.
go back to reference Disorders CECGoREaToS. Chinese expert consensus on evaluation and treatment of swallowing disorders. Chin J Phys Med Health. 2017;39(12):881–92. Disorders CECGoREaToS. Chinese expert consensus on evaluation and treatment of swallowing disorders. Chin J Phys Med Health. 2017;39(12):881–92.
18.
go back to reference Perry L. Screening swallowing function of patients with acute stroke. Part one: identification, implementation and initial evaluation of a screening tool for use by nurses. J Clin Nurs. 2001;10(4):463–73.CrossRefPubMed Perry L. Screening swallowing function of patients with acute stroke. Part one: identification, implementation and initial evaluation of a screening tool for use by nurses. J Clin Nurs. 2001;10(4):463–73.CrossRefPubMed
19.
go back to reference Cui F, Yin Q, Wu C, Shen M, Zhang Y, Ma C, Zhang H, Shen F. Capsaicin combined with ice stimulation improves swallowing function in patients with dysphagia after stroke: a randomised controlled trial. J Oral Rehabil. 2020;47(10):1297–303.CrossRefPubMed Cui F, Yin Q, Wu C, Shen M, Zhang Y, Ma C, Zhang H, Shen F. Capsaicin combined with ice stimulation improves swallowing function in patients with dysphagia after stroke: a randomised controlled trial. J Oral Rehabil. 2020;47(10):1297–303.CrossRefPubMed
20.
go back to reference Brodsky MB, Pandian V, Needham DM. Post-extubation dysphagia: a problem needing multidisciplinary efforts. Intensive Care Med. 2020;46(1):93–6.CrossRefPubMed Brodsky MB, Pandian V, Needham DM. Post-extubation dysphagia: a problem needing multidisciplinary efforts. Intensive Care Med. 2020;46(1):93–6.CrossRefPubMed
21.
go back to reference Fernando SM, Seely AJE. Post-extubation dysphagia: the truth is hard to swallow. Chest. 2020;158(5):1806–7.CrossRefPubMed Fernando SM, Seely AJE. Post-extubation dysphagia: the truth is hard to swallow. Chest. 2020;158(5):1806–7.CrossRefPubMed
22.
go back to reference El Gharib AZG, Berretin-Felix G, Rossoni DF, Seiji Yamada S. Effectiveness of therapy on post-extubation dysphagia: clinical and electromyographic findings. Clin Med Insights Ear Nose Throat. 2019;12:1179550619873364.CrossRefPubMedPubMedCentral El Gharib AZG, Berretin-Felix G, Rossoni DF, Seiji Yamada S. Effectiveness of therapy on post-extubation dysphagia: clinical and electromyographic findings. Clin Med Insights Ear Nose Throat. 2019;12:1179550619873364.CrossRefPubMedPubMedCentral
23.
go back to reference Park HS, Koo JH, Song SH. Association of post-extubation dysphagia with tongue weakness and somatosensory disturbance in non-neurologic critically Ill patients. Ann Rehabil Med. 2017;41(6):961–8.CrossRefPubMedPubMedCentral Park HS, Koo JH, Song SH. Association of post-extubation dysphagia with tongue weakness and somatosensory disturbance in non-neurologic critically Ill patients. Ann Rehabil Med. 2017;41(6):961–8.CrossRefPubMedPubMedCentral
24.
go back to reference Macht M, King CJ, Wimbish T, Clark BJ, Benson AB, Burnham EL, Williams A, Moss M. Post-extubation dysphagia is associated with longer hospitalization in survivors of critical illness with neurologic impairment. Crit Care. 2013;17(3):R119.CrossRefPubMedPubMedCentral Macht M, King CJ, Wimbish T, Clark BJ, Benson AB, Burnham EL, Williams A, Moss M. Post-extubation dysphagia is associated with longer hospitalization in survivors of critical illness with neurologic impairment. Crit Care. 2013;17(3):R119.CrossRefPubMedPubMedCentral
26.
go back to reference Macht M, Wimbish T, Clark BJ, Benson AB, Burnham EL, Williams A, Moss M. Diagnosis and treatment of post-extubation dysphagia: results from a national survey. J Crit Care. 2012;27(6):578–86.CrossRefPubMedPubMedCentral Macht M, Wimbish T, Clark BJ, Benson AB, Burnham EL, Williams A, Moss M. Diagnosis and treatment of post-extubation dysphagia: results from a national survey. J Crit Care. 2012;27(6):578–86.CrossRefPubMedPubMedCentral
27.
go back to reference Skoretz SA, Yau TM, Ivanov J, Granton JT, Martino R. Dysphagia and associated risk factors following extubation in cardiovascular surgical patients. Dysphagia. 2014;29(6):647–54.CrossRefPubMed Skoretz SA, Yau TM, Ivanov J, Granton JT, Martino R. Dysphagia and associated risk factors following extubation in cardiovascular surgical patients. Dysphagia. 2014;29(6):647–54.CrossRefPubMed
28.
go back to reference Hara K, Tohara H, Minakuchi S. Treatment and evaluation of dysphagia rehabilitation especially on suprahyoid muscles as jaw-opening muscles. Jpn Dent Sci Rev. 2018;54(4):151–9.CrossRefPubMedPubMedCentral Hara K, Tohara H, Minakuchi S. Treatment and evaluation of dysphagia rehabilitation especially on suprahyoid muscles as jaw-opening muscles. Jpn Dent Sci Rev. 2018;54(4):151–9.CrossRefPubMedPubMedCentral
29.
go back to reference Jintian Y, Junshan C, Aiqin Z. Meta-analysis of risk factors for acquired dysphagia after cardiac surgery. Chin J Nurs. 2020;18(16):9–13. Jintian Y, Junshan C, Aiqin Z. Meta-analysis of risk factors for acquired dysphagia after cardiac surgery. Chin J Nurs. 2020;18(16):9–13.
30.
go back to reference Yang WJ, Park E, Min YS, Huh JW, Kim AR, Oh HM, Nam TW, Jung TD. Association between clinical risk factors and severity of dysphagia after extubation based on a videofluoroscopic swallowing study. Korean J Intern Med. 2020;35(1):79–87.CrossRefPubMedPubMedCentral Yang WJ, Park E, Min YS, Huh JW, Kim AR, Oh HM, Nam TW, Jung TD. Association between clinical risk factors and severity of dysphagia after extubation based on a videofluoroscopic swallowing study. Korean J Intern Med. 2020;35(1):79–87.CrossRefPubMedPubMedCentral
31.
go back to reference Traugott M, Hoepler W, Kitzberger R, Pavlata S, Seitz T, Baumgartner S, Placher-Sorko G, Pirker-Krassnig D, Ehehalt U, Grasnek A, et al. Successful treatment of intubation-induced severe neurogenic post-extubation dysphagia using pharyngeal electrical stimulation in a COVID-19 survivor: a case report. J Med Case Rep. 2021;15(1):148.CrossRefPubMedPubMedCentral Traugott M, Hoepler W, Kitzberger R, Pavlata S, Seitz T, Baumgartner S, Placher-Sorko G, Pirker-Krassnig D, Ehehalt U, Grasnek A, et al. Successful treatment of intubation-induced severe neurogenic post-extubation dysphagia using pharyngeal electrical stimulation in a COVID-19 survivor: a case report. J Med Case Rep. 2021;15(1):148.CrossRefPubMedPubMedCentral
32.
go back to reference Medeiros GC, Sassi FC, Mangilli LD, Zilberstein B, Andrade CR. Clinical dysphagia risk predictors after prolonged orotracheal intubation. Clinics (Sao Paulo). 2014;69(1):8–14.CrossRefPubMed Medeiros GC, Sassi FC, Mangilli LD, Zilberstein B, Andrade CR. Clinical dysphagia risk predictors after prolonged orotracheal intubation. Clinics (Sao Paulo). 2014;69(1):8–14.CrossRefPubMed
33.
go back to reference Su H, Hsiao TY, Ku SC, Wang TG, Lee JJ, Tzeng WC, Huang GH, Chen CC. Tongue weakness and somatosensory disturbance following oral endotracheal extubation. Dysphagia. 2015;30(2):188–95.CrossRefPubMed Su H, Hsiao TY, Ku SC, Wang TG, Lee JJ, Tzeng WC, Huang GH, Chen CC. Tongue weakness and somatosensory disturbance following oral endotracheal extubation. Dysphagia. 2015;30(2):188–95.CrossRefPubMed
34.
go back to reference Kim G, Baek S, Park HW, Kang EK, Lee G. Effect of nasogastric tube on aspiration risk: results from 147 patients with dysphagia and literature review. Dysphagia. 2018;33(6):731–8.CrossRefPubMed Kim G, Baek S, Park HW, Kang EK, Lee G. Effect of nasogastric tube on aspiration risk: results from 147 patients with dysphagia and literature review. Dysphagia. 2018;33(6):731–8.CrossRefPubMed
35.
go back to reference Lynch YT, Clark BJ, Macht M, White SD, Taylor H, Wimbish T, Moss M. The accuracy of the bedside swallowing evaluation for detecting aspiration in survivors of acute respiratory failure. J Crit Care. 2017;39:143–8.CrossRefPubMedPubMedCentral Lynch YT, Clark BJ, Macht M, White SD, Taylor H, Wimbish T, Moss M. The accuracy of the bedside swallowing evaluation for detecting aspiration in survivors of acute respiratory failure. J Crit Care. 2017;39:143–8.CrossRefPubMedPubMedCentral
36.
go back to reference Na W, Yanling W, Chunyan Z. Analysis of the current status and risk factors of acquired dysphagia in ICU patients. Chin Nurs Manag. 2018;18(11):1467–71. Na W, Yanling W, Chunyan Z. Analysis of the current status and risk factors of acquired dysphagia in ICU patients. Chin Nurs Manag. 2018;18(11):1467–71.
37.
go back to reference Fan G, Mingming W, Shengqiang Z. Risk factors analysis and prediction model establishment of dysphagia after extubation in ICU patients with tracheal intubation. Nurs Res. 2020;19(12):12–6. Fan G, Mingming W, Shengqiang Z. Risk factors analysis and prediction model establishment of dysphagia after extubation in ICU patients with tracheal intubation. Nurs Res. 2020;19(12):12–6.
38.
go back to reference Oliveira ACM, Friche AAL, Salomao MS, Bougo GC, Vicente LCC. Predictive factors for oropharyngeal dysphagia after prolonged orotracheal intubation. Braz J Otorhinolaryngol. 2018;84(6):722–8.CrossRefPubMed Oliveira ACM, Friche AAL, Salomao MS, Bougo GC, Vicente LCC. Predictive factors for oropharyngeal dysphagia after prolonged orotracheal intubation. Braz J Otorhinolaryngol. 2018;84(6):722–8.CrossRefPubMed
39.
go back to reference Zhang Z, Perera S, Donohue C, Kurosu A, Mahoney AS, Coyle JL, Sejdic E. The prediction of risk of penetration-aspiration via hyoid bone displacement features. Dysphagia. 2020;35(1):66–72.CrossRefPubMed Zhang Z, Perera S, Donohue C, Kurosu A, Mahoney AS, Coyle JL, Sejdic E. The prediction of risk of penetration-aspiration via hyoid bone displacement features. Dysphagia. 2020;35(1):66–72.CrossRefPubMed
40.
go back to reference Schefold JC, Berger D, Zurcher P, Lensch M, Perren A, Jakob SM, Parviainen I, Takala J. Dysphagia in mechanically ventilated ICU patients (DYnAMICS): a prospective observational trial. Crit Care Med. 2017;45(12):2061–9.CrossRefPubMed Schefold JC, Berger D, Zurcher P, Lensch M, Perren A, Jakob SM, Parviainen I, Takala J. Dysphagia in mechanically ventilated ICU patients (DYnAMICS): a prospective observational trial. Crit Care Med. 2017;45(12):2061–9.CrossRefPubMed
41.
go back to reference Laham JL, Breheny PJ, Rush A. Do clinical parameters predict first planned extubation outcome in the pediatric intensive care unit? J Intensive Care Med. 2015;30(2):89–96.CrossRefPubMed Laham JL, Breheny PJ, Rush A. Do clinical parameters predict first planned extubation outcome in the pediatric intensive care unit? J Intensive Care Med. 2015;30(2):89–96.CrossRefPubMed
Metadata
Title
RETRACTED ARTICLE: The Characteristics and Predicators of Post-extubation Dysphagia in ICU Patients with Endotracheal Intubation
Authors
Chenyun Xia
Jianhong Ji
Publication date
21-06-2022
Publisher
Springer US
Published in
Dysphagia / Issue 1/2023
Print ISSN: 0179-051X
Electronic ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-022-10462-0

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