Published in:
01-12-2009 | Editorial Comment
Cardiopulmonary exercise testing in thalassemia
Authors:
John-Paul Carpenter, Dudley J. Pennell
Published in:
The International Journal of Cardiovascular Imaging
|
Issue 8/2009
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Excerpt
In this issue of International Journal of Cardiac Imaging, researchers from the Onassis Cardiac Surgery Centre and Agia Sophia Hospital in Athens report their findings of cardiopulmonary exercise testing (CPET) in relation to cardiovascular magnetic resonance (CMR) in patients with thalassemia major (TM) [
1]. In support of previously available evidence, they found raised cardiac iron and low left ventricular ejection fraction in patients with heart failure. In addition, CPET indices (VO
2max, anaerobic threshold (AT), metabolic equivalents (METs) and exercise duration) were not only lower in TM patients with heart failure but were closely correlated with iron loading, measured by CMR T2*. …