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Open Access 01-12-2021 | Cardiomyopathy | Research article

Impact of tricuspid regurgitation on late right ventricular failure in left ventricular assist device patients ~can prophylactic tricuspid annuloplasty prevent late right ventricular failure? ~

Authors: Taro Nakazato, Daisuke Yoshioka, Koichi Toda, Shigeru Miyagawa, Satoshi Kainuma, Takuji Kawamura, Ai Kawamura, Noriyuki Kashiyama, Takayoshi Ueno, Toru Kuratani, Yasushi Sakata, Yoshiki Sawa

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

Abstract

Background

In this study, we evaluated the prevalence of tricuspid regurgitation (TR) worsening in patients with left ventricular assist devices (LVADs) and its impact on late right ventricular (RV) failure.

Methods

We enrolled 147 patients of the 184 patients who underwent continuous-flow LVAD implantations from 2005 to March 2018. The prevalence of postoperative TR worsening and late RV failure were retrospectively evaluated.

Results

Concomitant tricuspid annuloplasty (TAP) was performed in 28 of 41 patients (68%) with preoperative TR greater than or equal to moderate (TR group) and in 23 of 106 patients (22%) with preoperative TR less than or equal to mild (non-TR group). Regarding the TR-free rates, despite receiving or not receiving concomitant TAP, there was no significant difference between the 2 groups (TR group: p = 0.37; non-TR group: p = 0.42). Of the 9 patients with postoperative TR greater than or equal to moderate, late RV failure developed in 3 patients, with TR worsening after RV failure in each case. During follow-up, 16 patients (11%) had late RV failure. As for the late RV failure-free rates, despite receiving or not receiving concomitant TAP, there was no significant difference between the 2 groups (TR group: p = 0.37; non-TR group: p = 0.96).

Conclusions

TR prognosis was preferable regardless of a patient receiving concomitant TAP; however, the presence of postoperative TR seemed to unrelated to late RV failure. Prophylactic TAP might not be necessary to prevent late RV failure.

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Title: Impact of tricuspid regurgitation on late right ventricular failure in left ventricular assist device patients ~can prophylactic tricuspid annuloplasty prevent late right ventricular failure? ~
Authors: Taro Nakazato
Daisuke Yoshioka
Koichi Toda
Shigeru Miyagawa
Satoshi Kainuma
Takuji Kawamura
Ai Kawamura
Noriyuki Kashiyama
Takayoshi Ueno
Toru Kuratani
Yasushi Sakata
Yoshiki Sawa
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Cardiomyopathy
Implantable Cardioverter Defibrillator
Heart Failure
Published in: Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-021-01492-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impact of tricuspid regurgitation on late right ventricular failure in left ventricular assist device patients ~can prophylactic tricuspid annuloplasty prevent late right ventricular failure? ~

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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