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Journal of Cardiothoracic Surgery

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Open Access 01-12-2021 | Acute Kidney Injury | Research article

Body mass index is an independent predictor of acute kidney injury after urgent aortic arch surgery for acute DeBakey Type I aortic dissection

Authors: Taoshuai Liu, Yuwei Fu, Jie Liu, Yongmin Liu, Junming Zhu, Lizhong Sun, Ming Gong, Ran Dong, Hongjia Zhang

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

Abstract

Background

Aortic arch surgery and obesity are both related to the risk of acute kidney injury. Our hypothesis was that the risk of postoperative acute kidney injury increases as body mass index increases in patients undergoing urgent aortic total arch replacement surgery for acute DeBakey Type I aortic dissection.

Methods

We conducted a retrospective cohort study in Beijing Anzhen Hospital from December 2015 to April 2017. All patients receiving urgent aortic total arch replacement surgery with a frozen elephant trunk implant for acute DeBakey Type I aortic dissection were included. Body mass index was calculated based on height and weight. Acute kidney injury was diagnosed based on the Kidney Disease Improving Global Outcomes standards.

Results

We included 115 consecutive patients in this study. A total of 53.0% (n = 61) of patients had acute kidney injury. The mean age was 47.8 ± 10.7 years, and 25.2% were women. Mean body mass index was 26.2 ± 3.9 kg/m². The results of a univariate analysis showed that BMI, eGFR, CPB time, operative time, intraoperative blood loss, intraoperative amount of PRBCs, and respiratory failure were significantly correlated with AKI. In-hospital mortality was obviously increased in the acute kidney injury group (13.1% vs 1.9%; P = 0.025). Multivariate logistic regression showed that body mass index was associated with postoperative acute kidney injury after adjusting for other confounding factors (odds ratio = 1.16; 95% confidence interval: 1.02–1.33; P = 0.0288). The risk of postoperative AKI in the BMI ≥ 24 kg/m² group was increased by 2.35 times (OR = 3.35, 95% CI: 1.15–9.74; p = 0.0263).

Conclusions

Body mass index was an independent predictor of acute kidney injury after urgent aortic total arch replacement surgery with a frozen elephant trunk implant.

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Title: Body mass index is an independent predictor of acute kidney injury after urgent aortic arch surgery for acute DeBakey Type I aortic dissection
Authors: Taoshuai Liu
Yuwei Fu
Jie Liu
Yongmin Liu
Junming Zhu
Lizhong Sun
Ming Gong
Ran Dong
Hongjia Zhang
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Acute Kidney Injury
Circulatory Arrest
Acute Kidney Injury
Aortic Dissection
Published in: Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-021-01533-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Body mass index is an independent predictor of acute kidney injury after urgent aortic arch surgery for acute DeBakey Type I aortic dissection

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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