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Heart Failure Reviews
Published in: Heart Failure Reviews 2/2024

02-12-2023 | Cardiomyopathy

Multidisciplinary approach in cardiomyopathies: From genetics to advanced imaging

Authors: Francesco Santoro, Enrica Vitale, Ilaria Ragnatela, Rosa Cetera, Alessandra Leopzzi, Adriana Mallardi, Annalisa Matera, Marco Mele, Michele Correale, Natale Daniele Brunetti

Published in: Heart Failure Reviews | Issue 2/2024

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Abstract

Cardiomyopathies are myocardial diseases characterized by mechanical and electrical dysfunction of the heart muscle which could lead to heart failure and life-threatening arrhythmias. Certainly, an accurate anamnesis, a meticulous physical examination, and an ECG are cornerstones in raising the diagnostic suspicion. However, cardiovascular imaging techniques are indispensable to diagnose a specific cardiomyopathy, to stratify the risk related to the disease and even to track the response to the therapy. Echocardiography is often the first exam that the patient undergoes, because of its non-invasiveness, wide availability, and cost-effectiveness. Cardiac magnetic resonance imaging allows to integrate and implement the information obtained with the echography. Furthermore, cardiomyopathies’ genetic basis has been investigated over the years and the list of genetic mutations deemed potentially pathogenic is expected to grow further. The aim of this review is to show echocardiographic, cardiac magnetic resonance imaging, and genetic features of several cardiomyopathies: dilated cardiomyopathy (DMC), hypertrophic cardiomyopathy (HCM), arrhythmogenic cardiomyopathy (ACM), left ventricular noncompaction cardiomyopathy (LVNC), myocarditis, and takotsubo cardiomyopathy.
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Metadata
Title
Multidisciplinary approach in cardiomyopathies: From genetics to advanced imaging
Authors
Francesco Santoro
Enrica Vitale
Ilaria Ragnatela
Rosa Cetera
Alessandra Leopzzi
Adriana Mallardi
Annalisa Matera
Marco Mele
Michele Correale
Natale Daniele Brunetti
Publication date
02-12-2023
Publisher
Springer US
Published in
Heart Failure Reviews / Issue 2/2024
Print ISSN: 1382-4147
Electronic ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-023-10373-8

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