Skip to main content
Top
Published in: Journal of Nuclear Cardiology 4/2020

01-08-2020 | Cardiomyopathy | Images that Teach

Non-biopsy diagnosis of familial amyloid cardiomyopathy

Authors: Laroussi Mohamed-Salem, MD, PhD, Tatiana Moreno-Monsalve, MD, Mª Isabel Castellón-Sánchez, MD, Mª Antonia Claver-Valderas, MD, Domingo Pascual-Figal, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 4/2020

Login to get access

Excerpt

An 84-year-old male, former smoker yet without other cardiovascular risk factors, has a history of carpal tunnel syndrome, chronic axonal sensorimotor polyneuropathy moderate to a severe degree, more prominent in the lower extremities, colonic diverticulosis, and large internal hemorrhoids. The patient has a family history of cardiomyopathy, with both fathers and five of his seven brothers died of cardiomyopathy, an unknown etiological diagnosis. …
Literature
1.
go back to reference Falk RH, Quarta CC, Dorbala S. How to image cardiac amyloidosis: A focused practical review. Circ Cardiovasc Imaging. 2014;7:552–62.CrossRef Falk RH, Quarta CC, Dorbala S. How to image cardiac amyloidosis: A focused practical review. Circ Cardiovasc Imaging. 2014;7:552–62.CrossRef
2.
go back to reference Mohamed-Salem L, Santos-Mateo JJ, Sanchez-Serna J, Hernandez-Vicente A, Reyes-Marle R, Castellon Sanchez MI, et al. Prevalence of wild type ATTR assessed as myocardial uptake in bone scan in the elderly population. Int J Cardiol. 2018;270:192–6.CrossRef Mohamed-Salem L, Santos-Mateo JJ, Sanchez-Serna J, Hernandez-Vicente A, Reyes-Marle R, Castellon Sanchez MI, et al. Prevalence of wild type ATTR assessed as myocardial uptake in bone scan in the elderly population. Int J Cardiol. 2018;270:192–6.CrossRef
3.
go back to reference Pellikka PA, Holmes DR, Edwards WD, Nishimura RA, Tajik AJ, Kyle RA. Endomyocardial biopsy in 30 patients with primary amyloidosis and suspected cardiac involvement. Arch intern Med. 1988;148:662–6.CrossRef Pellikka PA, Holmes DR, Edwards WD, Nishimura RA, Tajik AJ, Kyle RA. Endomyocardial biopsy in 30 patients with primary amyloidosis and suspected cardiac involvement. Arch intern Med. 1988;148:662–6.CrossRef
4.
go back to reference Gertz MA, Benson MD, Dyck PJ, Grogan M, Coelho T, Cruz M, Berk JL, Plante-Bordeneuve V, Schmidt HHJ, Merlini G. Diagnosis, prognosis, and therapy of transthyretin amyloidosis. J Am Coll Cardiol. 2015;66:2451–66.CrossRef Gertz MA, Benson MD, Dyck PJ, Grogan M, Coelho T, Cruz M, Berk JL, Plante-Bordeneuve V, Schmidt HHJ, Merlini G. Diagnosis, prognosis, and therapy of transthyretin amyloidosis. J Am Coll Cardiol. 2015;66:2451–66.CrossRef
5.
go back to reference Haro-del F, Sánchez A, Gómez M, García P, Salas-Antón C, Segovia-Cubero J. Role of cardiac scintigraphy with 99mTC-DPD in the discrimination of the cardiac amyloidosis subtype. Rev Esp Cardiol. 2012;65:440–6.CrossRef Haro-del F, Sánchez A, Gómez M, García P, Salas-Antón C, Segovia-Cubero J. Role of cardiac scintigraphy with 99mTC-DPD in the discrimination of the cardiac amyloidosis subtype. Rev Esp Cardiol. 2012;65:440–6.CrossRef
6.
go back to reference Maurer SM. Non-invasive identification of ATTRwt cardiac amyloid (aka senile cardiac amyloid): The re-emergence of nuclear cardiology. Am J Med. 2015;128:1275–80.CrossRef Maurer SM. Non-invasive identification of ATTRwt cardiac amyloid (aka senile cardiac amyloid): The re-emergence of nuclear cardiology. Am J Med. 2015;128:1275–80.CrossRef
7.
go back to reference Idiazabal U, Garcia Pavia P, Azcarate P, Idoate F, Mercado M. Transthyretin amyloidosis: Scintigraphy showing the way. Rev Colomb Cardiol. 2016;23:71.e1–5. Idiazabal U, Garcia Pavia P, Azcarate P, Idoate F, Mercado M. Transthyretin amyloidosis: Scintigraphy showing the way. Rev Colomb Cardiol. 2016;23:71.e1–5.
8.
go back to reference Gillmore JD, Maurer MS, Falk RH, et al. Nonbiopsy diagnosis of cardiac transthyretin amyloidosis. Circulation. 2016;133:2404–12.CrossRef Gillmore JD, Maurer MS, Falk RH, et al. Nonbiopsy diagnosis of cardiac transthyretin amyloidosis. Circulation. 2016;133:2404–12.CrossRef
9.
go back to reference Singh V, Falk R, Di Carli MF, Kijewski M, Rapezzi C, Dorbala S. State-of-the-art radionuclide imaging in cardiac transthyretin amyloidosis. J Nucl Cardiol. 2019;26:158–73.CrossRef Singh V, Falk R, Di Carli MF, Kijewski M, Rapezzi C, Dorbala S. State-of-the-art radionuclide imaging in cardiac transthyretin amyloidosis. J Nucl Cardiol. 2019;26:158–73.CrossRef
10.
go back to reference Pilebro B, Suhr OB, Naslund U, Westermark P, Lindqvist P, Sundstrom T. (99m)Tc-DPD uptake reflects amyloid fibril composition in hereditary transthyretin amyloidosis. Ups J Med Sci. 2016;121:17–24.CrossRef Pilebro B, Suhr OB, Naslund U, Westermark P, Lindqvist P, Sundstrom T. (99m)Tc-DPD uptake reflects amyloid fibril composition in hereditary transthyretin amyloidosis. Ups J Med Sci. 2016;121:17–24.CrossRef
11.
go back to reference Pilebro B, Arvidsson S, Lindqvist P, Sundstrom T, Westermark P, Antoni G, et al. Positron emission tomography (PET) utilizing Pittsburgh compound B (PIB) for detection of amyloid heart deposits in hereditary transthyretin amyloidosis (ATTR). J Nucl Cardiol. 2018;25:240–8.CrossRef Pilebro B, Arvidsson S, Lindqvist P, Sundstrom T, Westermark P, Antoni G, et al. Positron emission tomography (PET) utilizing Pittsburgh compound B (PIB) for detection of amyloid heart deposits in hereditary transthyretin amyloidosis (ATTR). J Nucl Cardiol. 2018;25:240–8.CrossRef
Metadata
Title
Non-biopsy diagnosis of familial amyloid cardiomyopathy
Authors
Laroussi Mohamed-Salem, MD, PhD
Tatiana Moreno-Monsalve, MD
Mª Isabel Castellón-Sánchez, MD
Mª Antonia Claver-Valderas, MD
Domingo Pascual-Figal, MD, PhD
Publication date
01-08-2020
Publisher
Springer International Publishing
Published in
Journal of Nuclear Cardiology / Issue 4/2020
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-019-01700-4

Other articles of this Issue 4/2020

Journal of Nuclear Cardiology 4/2020 Go to the issue