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01-12-2021 | Cardiomyopathy | EDITORIAL

Left ventricular mechanical dyssynchrony in patient with CAD: The Saga continues

Author: Wael AlJaroudi, MD, FASNC

Published in: Journal of Nuclear Cardiology | Issue 6/2021

Excerpt

Left ventricular mechanical dyssynchrony (LVMD) by phase analysis of gated single-photon emission computed tomography (SPECT) was initially introduced by Chen et al in 2005 as a simple reliable tool that is reproducible and repeatable, performed retrospectively on previously acquired gated images, and without the need for additional imaging.1,2 …

Chen J, Garcia EV, Folks RD, Cooke CD, Faber TL, Tauxe EL, et al. Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion spect imaging: Development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. J Nucl Cardiol 2005;12:687-95.CrossRef

Lin X, Xu H, Zhao X, Folks RD, Garcia EV, Soman P, et al. Repeatability of left ventricular dyssynchrony and function parameters in serial gated myocardial perfusion spect studies. J Nucl Cardiol 2010;17:811-6.CrossRef

Henneman MM, Chen J, Dibbets-Schneider P, Stokkel MP, Bleeker GB, Ypenburg C, et al. Can lv dyssynchrony as assessed with phase analysis on gated myocardial perfusion spect predict response to crt? J Nucl Med 2007;48:1104-11.CrossRef

Boogers MM, Van Kriekinge SD, Henneman MM, Ypenburg C, Van Bommel RJ, Boersma E, et al. Quantitative gated spect-derived phase analysis on gated myocardial perfusion spect detects left ventricular dyssynchrony and predicts response to cardiac resynchronization therapy. J Nucl Med 2009;50:718-25.CrossRef

Tao N, Qiu Y, Tang H, Qian Z, Wu H, Zhu R, et al. Assessment of left ventricular contraction patterns using gated spect mpi to predict cardiac resynchronization therapy response. J Nucl Cardiol 2018;25:2029-38.CrossRef

AlJaroudi W. Mechanical dyssynchrony with phase analysis of gated spect: Nap time is over. J Nucl Cardiol 2018;25:2039-43.CrossRef

Boogers MJ, Chen J, van Bommel RJ, Borleffs CJ, Dibbets-Schneider P, van der Hiel B, et al. Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion spect. Eur J Nucl Med Mol Imaging 2011;38:230-8.CrossRef

Igarashi Y, Chikamori T, Hida S, Tanaka H, Shiba C, Usui Y, et al. Usefulness of phase analysis to differentiate ischemic and non-ischemic etiologies of left ventricular systolic dysfunction in patients with heart failure. Circ J 2014;78:141-50.CrossRef

AlJaroudi W. Mechanical dyssynchrony & crt: Is it time for guideline updates? J Nucl Cardiol 2019

10.

Aljaroudi WA, Hage FG, Hermann D, Doppalapudi H, Venkataraman R, Heo J, et al. Relation of left-ventricular dyssynchrony by phase analysis of gated spect images and cardiovascular events in patients with implantable cardiac defibrillators. J Nucl Cardiol 2010;17:398-404.CrossRef

11.

Uebleis C, Hellweger S, Laubender RP, Becker A, Sohn HY, Lehner S, et al. Left ventricular dyssynchrony assessed by gated spect phase analysis is an independent predictor of death in patients with advanced coronary artery disease and reduced left ventricular function not undergoing cardiac resynchronization therapy. Eur J Nucl Med Mol Imaging 2012;39:1561-9.CrossRef

12.

Hess PL, Shaw LK, Fudim M, Iskandrian AE, Borges-Neto S. The prognostic value of mechanical left ventricular dyssynchrony defined by phase analysis from gated single-photon emission computed tomography myocardial perfusion imaging among patients with coronary heart disease. J Nucl Cardiol 2017;24:482-90.CrossRef

13.

Cho SG, Jabin Z, Park KS, Kim J, Kang SR, Kwon SY, et al. Clinical values of left ventricular mechanical dyssynchrony assessment by gated myocardial perfusion spect in patients with acute myocardial infarction and multivessel disease. Eur J Nucl Med Mol Imaging 2017;44:259-66.CrossRef

14.

Goldberg AS, Alraies MC, Cerqueira MD, Jaber WA, Aljaroudi WA. Prognostic value of left ventricular mechanical dyssynchrony by phase analysis in patients with non-ischemic cardiomyopathy with ejection fraction 35-50% and qrs < 150 ms. J Nucl Cardiol 2014;21:57-66.CrossRef

15.

Caobelli F, Popescu CE, Laudicella R, Comis A, Pignata SA, Sara R, et al. Predictive and prognostic value of left ventricular mechanical dyssynchrony assessed by myocardial perfusion single photon emission computed tomography in asymptomatic patients under hemodialysis. Nucl Med Commun 2018;39:423-9.CrossRef

16.

Gimelli A, Liga R, Giorgetti A, Favilli B, Pasanisi EM, Marzullo P. Determinants of left ventricular mechanical dyssynchrony in patients submitted to myocardial perfusion imaging: A cardiac czt study. J Nucl Cardiol 2016;23:728-36.CrossRef

17.

Hämäläinen H, Corovai A, Laitinen J, Laitinen T, Hedman M, Hedman A, et al. Myocardial ischemia and previous infarction contribute to left ventricular dyssynchrony in patients with coronary artery disease J Nucl Cardiol (ahead of print) 2020

18.

Hida S, Chikamori T, Tanaka H, Igarashi Y, Shiba C, Usui Y, et al. Diagnostic value of left ventricular dyssynchrony after exercise and at rest in the detection of multivessel coronary artery disease on single-photon emission computed tomography. Circ J 2012;76:1942-52.CrossRef

19.

Singh H, Patel CD, Sharma P, Naik N, Singh S, Narang R. Does perfusion pattern influence stress-induced changes in left ventricular mechanical dyssynchrony on thallium-201-gated spect myocardial perfusion imaging? J Nucl Cardiol 2015;22:36-43.CrossRef

20.

AlJaroudi W, Alraies MC, DiFilippo F, Brunken RC, Cerqueira MD, Jaber WA. Effect of stress testing on left ventricular mechanical synchrony by phase analysis of gated positron emission tomography in patients with normal myocardial perfusion. Eur J Nucl Med Mol Imaging 2012;39:665-72.CrossRef

21.

Fudim M, Fathallah M, Shaw LK, Liu PR, James O, Samad Z, et al. The prognostic value of diastolic and systolic mechanical left ventricular dyssynchrony among patients with coronary heart disease. JACC Cardiovasc Imaging 2019;12:1215-26.CrossRef

22.

Murrow J, Esteves F, Galt J, Chen J, Garcia E, Lin J, et al. Characterization of mechanical dyssynchrony measured by gated single photon emission computed tomography phase analysis after acute st-elevation myocardial infarction. J Nucl Cardiol 2011;18:912-9.CrossRef

23.

Schepis T, Gaemperli O, Koepfli P, Namdar M, Valenta I, Scheffel H, et al. Added value of coronary artery calcium score as an adjunct to gated spect for the evaluation of coronary artery disease in an intermediate-risk population. J Nucl Med 2007;48:1424-30.CrossRef

24.

Edalat-Javid M, Shiri I, Hajianfar G, Abdollahi H, Arabi H, Oveisi N, et al. Cardiac spect radiomic features repeatability and reproducibility: A multi-scanner phantom study. J Nucl Cardiol 2020

25.

Currie G, Iqbal B, Kiat H. Intelligent imaging: Radiomics and artificial neural networks in heart failure. J Med Imaging Radiat Sci 2019;50:571-4.CrossRef

Title: Left ventricular mechanical dyssynchrony in patient with CAD: The Saga continues
Author: Wael AlJaroudi, MD, FASNC
Publication date: 01-12-2021
Publisher: Springer International Publishing
Keywords: Cardiomyopathy
Arterial Diseases
Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy
Published in: Journal of Nuclear Cardiology / Issue 6/2021
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-020-02318-7

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