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Published in: Current Cardiology Reports 4/2017

01-04-2017 | Cardio-Oncology (SA Francis, Section Editor)

Cardio-oncology: the Nuclear Option

Authors: Jorge A. Alvarez, Raymond R. Russell

Published in: Current Cardiology Reports | Issue 4/2017

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Abstract

Purpose of Review

Cardio-oncology focuses increased effort to decrease cancer treatment-related cardiotoxicity while continuing to improve outcomes. We sought to synthesize the latest in nuclear cardiology as it pertains to the assessment of left ventricular function in preventative guidelines and comparison to other modalities, novel molecular markers of pre-clinical cardiotoxicity, and its role in cardiac amyloid diagnosis.

Recent Findings

Planar ERNA (equilibrium radionuclide angiocardiography) provides a reliable and proven means of monitoring and preventing anthracycline cardiotoxicity, and SPECT ERNA using solid-state gamma cameras may provide reproducible assessments of left ventricular function with reduced radiation exposure. While certain chemotherapeutics have vascular side effects, the use of stress perfusion imaging has still not been adequately studied for routine use. Similarly, markers of apoptosis, inflammation, and sympathetic nerve dysfunction are promising, but are still not ready for uniform usage. SPECT tracers can assist in nonbiopsy diagnosis of cardiac amyloid.

Summary

Nuclear cardiology is a significant contributor to the multimodality approach to cardio-oncology.
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Metadata
Title
Cardio-oncology: the Nuclear Option
Authors
Jorge A. Alvarez
Raymond R. Russell
Publication date
01-04-2017
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 4/2017
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-017-0844-z

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