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Published in: BMC Infectious Diseases 1/2005

Open Access 01-12-2005 | Case report

Cardiac involvement in a patient with clinical and serological evidence of African tick-bite fever

Authors: Cristina Bellini, Matteo Monti, Mathieu Potin, Anne Dalle Ave, Jacques Bille, Gilbert Greub

Published in: BMC Infectious Diseases | Issue 1/2005

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Abstract

Background

Myocarditis and pericarditis are rare complications of rickettsiosis, usually associated with Rickettsia rickettsii and R. conorii. African tick-bite fever (ATBF) is generally considered as a benign disease and no cases of myocardial involvement due to Rickettsia africae, the agent of ATBF, have yet been described.

Case presentation

The patient, that travelled in an endemic area, presented typical inoculation eschars, and a seroconversion against R. africae, was admitted for chest pains and increased cardiac enzymes in the context of an acute myocarditis.

Conclusion

Our findings suggest that ATBF, that usually presents a benign course, may be complicated by an acute myocarditis.
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Literature
1.
go back to reference Shah SS, McGowan JP: Rickettsial, ehrlichial and Bartonella infections of the myocardium and pericardium. Front Biosci. 2003, 1 (8): 197-201.CrossRef Shah SS, McGowan JP: Rickettsial, ehrlichial and Bartonella infections of the myocardium and pericardium. Front Biosci. 2003, 1 (8): 197-201.CrossRef
2.
go back to reference Marin-Garcia J, Gooch WM, Coury DL: Cardiac manifestations of Rocky Mountain spotted fever. Pediatrics. 1981, 67: 358-61.PubMed Marin-Garcia J, Gooch WM, Coury DL: Cardiac manifestations of Rocky Mountain spotted fever. Pediatrics. 1981, 67: 358-61.PubMed
3.
go back to reference Drancourt M, Brouqui P, Chiche G, Raoult D: Acute pericarditis in Mediterranean Spotted Fever. Trans R Soc Trop Med Hyg. 1991, 85: 799-10.1016/0035-9203(91)90461-7.CrossRefPubMed Drancourt M, Brouqui P, Chiche G, Raoult D: Acute pericarditis in Mediterranean Spotted Fever. Trans R Soc Trop Med Hyg. 1991, 85: 799-10.1016/0035-9203(91)90461-7.CrossRefPubMed
4.
go back to reference Kelly PJ, Beati L, Mason PR, Matthewman LA, Roux V, Raoult D: Rickettsia africae sp nov, the etiological agent of African tick bite fever. Int J Syst Bact. 1996, 46: 611-4.CrossRef Kelly PJ, Beati L, Mason PR, Matthewman LA, Roux V, Raoult D: Rickettsia africae sp nov, the etiological agent of African tick bite fever. Int J Syst Bact. 1996, 46: 611-4.CrossRef
5.
go back to reference Jensenius M, Fournier PE, Vene S, Hoel T, Hasle G, Henriksen AZ, Hellum KB, Raoult D, Myrvang B: African tick bite fever in travelers to rural sub-Equatorial Africa. Clin Infect Dis. 2003, 36: 1411-7. 10.1086/375083.CrossRefPubMed Jensenius M, Fournier PE, Vene S, Hoel T, Hasle G, Henriksen AZ, Hellum KB, Raoult D, Myrvang B: African tick bite fever in travelers to rural sub-Equatorial Africa. Clin Infect Dis. 2003, 36: 1411-7. 10.1086/375083.CrossRefPubMed
6.
go back to reference Ndip LM, Fokam EB, Bouyer DH, Ndip RN, Titanji VP, Walker DH, McBride JW: Detection of Rickettsia africae in patients and ticks along the coastal region of Cameroon. Am J Trop Med Hyg. 2004, 71: 363-6.PubMed Ndip LM, Fokam EB, Bouyer DH, Ndip RN, Titanji VP, Walker DH, McBride JW: Detection of Rickettsia africae in patients and ticks along the coastal region of Cameroon. Am J Trop Med Hyg. 2004, 71: 363-6.PubMed
7.
go back to reference Fournier PE, Roux V, Caumes E, Donzel M, Raoult D: Outbreak of Rickettsia africae infections in participants of an adventure race in South Africa. Clin Infect Dis. 1998, 27: 316-23.CrossRefPubMed Fournier PE, Roux V, Caumes E, Donzel M, Raoult D: Outbreak of Rickettsia africae infections in participants of an adventure race in South Africa. Clin Infect Dis. 1998, 27: 316-23.CrossRefPubMed
8.
go back to reference Raoult D, Fournier PE, Fenollar F, Jensenius M, Prioe T, de Pina JJ, Caruso G, Jones N, Laferl H, Rosenblatt JE, Marrie TJ: Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa. N Engl J Med. 2001, 344: 1504-10. 10.1056/NEJM200105173442003.CrossRefPubMed Raoult D, Fournier PE, Fenollar F, Jensenius M, Prioe T, de Pina JJ, Caruso G, Jones N, Laferl H, Rosenblatt JE, Marrie TJ: Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa. N Engl J Med. 2001, 344: 1504-10. 10.1056/NEJM200105173442003.CrossRefPubMed
9.
go back to reference Jackson Y, Chappuis F, Loutan L: African tick-bite fever: four cases among Swiss travelers returning from South Africa. J Travel Med. 2004, 11: 225-8.CrossRefPubMed Jackson Y, Chappuis F, Loutan L: African tick-bite fever: four cases among Swiss travelers returning from South Africa. J Travel Med. 2004, 11: 225-8.CrossRefPubMed
10.
go back to reference Jensenius M, Fournier PE, Raoult D: Tick-borne rickettsioses in international travellers. Int J Infect Dis. 2004, 8: 139-46. 10.1016/j.ijid.2003.06.004.CrossRefPubMed Jensenius M, Fournier PE, Raoult D: Tick-borne rickettsioses in international travellers. Int J Infect Dis. 2004, 8: 139-46. 10.1016/j.ijid.2003.06.004.CrossRefPubMed
11.
go back to reference Fournier PE, Jensenius M, Laferl H, Vene S, Raoult D: Kinetics of antibody responses in Rickettsia africae and Rickettsia conorii infections. Clin Diagn Lab Immunol. 2002, 9: 324-8. 10.1128/CDLI.9.2.324-328.2002.PubMedPubMedCentral Fournier PE, Jensenius M, Laferl H, Vene S, Raoult D: Kinetics of antibody responses in Rickettsia africae and Rickettsia conorii infections. Clin Diagn Lab Immunol. 2002, 9: 324-8. 10.1128/CDLI.9.2.324-328.2002.PubMedPubMedCentral
12.
go back to reference Walker DH, Valbuena GA, Olano JP: Pathogenic mechanisms of diseases caused by Rickettsia. Ann N Y Acad Sci. 2003, 990: 1-11.CrossRefPubMed Walker DH, Valbuena GA, Olano JP: Pathogenic mechanisms of diseases caused by Rickettsia. Ann N Y Acad Sci. 2003, 990: 1-11.CrossRefPubMed
13.
go back to reference Feldman AM and McNamara D: Myocarditis. N Engl J Med. 2000, 343: 1388-1398. 10.1056/NEJM200011093431908.CrossRefPubMed Feldman AM and McNamara D: Myocarditis. N Engl J Med. 2000, 343: 1388-1398. 10.1056/NEJM200011093431908.CrossRefPubMed
14.
go back to reference Smith SC, Ladenson JH, Mason JW, Jaffe AS: Elevations of cardiac troponin I associated with myocarditis. Experimental and clinical correlates. Circulation. 1997, 95: 163-8.CrossRefPubMed Smith SC, Ladenson JH, Mason JW, Jaffe AS: Elevations of cardiac troponin I associated with myocarditis. Experimental and clinical correlates. Circulation. 1997, 95: 163-8.CrossRefPubMed
15.
go back to reference Hamm CW, Giannitsis E, Katus HA: Cardiac troponin elevations in patients without acute coronary syndrome. Circulation. 2002, 106: 2871-2. 10.1161/01.CIR.0000044342.50593.63.CrossRefPubMed Hamm CW, Giannitsis E, Katus HA: Cardiac troponin elevations in patients without acute coronary syndrome. Circulation. 2002, 106: 2871-2. 10.1161/01.CIR.0000044342.50593.63.CrossRefPubMed
Metadata
Title
Cardiac involvement in a patient with clinical and serological evidence of African tick-bite fever
Authors
Cristina Bellini
Matteo Monti
Mathieu Potin
Anne Dalle Ave
Jacques Bille
Gilbert Greub
Publication date
01-12-2005
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2005
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/1471-2334-5-90

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