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01-09-2016 | Capsule Commentary

Capsule Commentary on Phibbs et. al., At-Home versus In-Clinic INR Monitoring: A Cost-Utility Analysis from The Home INR Study (THINRS)

Author: William J. Canestaro, MSc

Published in: Journal of General Internal Medicine | Issue 9/2016

Excerpt

Warfarin can substantially reduce the risk of ischemic stroke, but has significant limitations, including an increased risk of bleeding, inconvenient monitoring, and interactions with numerous foods and drugs. As a result, the quality of warfarin use has been less than optimal.1 This has led to a search for viable alternatives, including patient self-monitoring. A recent meta-analysis of 22 studies found that self-testing improved outcomes, but could not judge its cost-effectiveness.2 The current study by Phibbs et al.3 addresses this gap in evidence. …

Baker WL, Cios DA, Sander SD, Coleman CI. Meta-analysis to assess the quality of warfarin control in atrial fibrillation patients in the United States. J Manag Care Pharm. 2009;15:244–52.PubMed

Bloomfield HE, Krause A, Greer N, et al. Meta-analysis: effect of patient self-testing and self-management of long-term anticoagulation on major clinical outcomes. Ann Intern Med. 2011;154:472–82.CrossRefPubMed

Phibbs CS, Love SR, Jacobson AK, Edson R, Su P, Uyeda L, Matchar DB. At-Home versus In-Clinic INR monitoring: a cost-utility analysis from The Home INR Study (THINRS). J Gen Intern Med. 2016. doi:10.1007/s11606-016-3700-8.PubMed

Matchar DB, Jacobson A, Dolor R, Dolor R, Edson R, et al. Effect of home testing of international normalized ratio on clinical events. N Engl J Med. 2010;363:1608–20.CrossRefPubMed

Title: Capsule Commentary on Phibbs et. al., At-Home versus In-Clinic INR Monitoring: A Cost-Utility Analysis from The Home INR Study (THINRS)
Author: William J. Canestaro, MSc
Publication date: 01-09-2016
Publisher: Springer US
Published in: Journal of General Internal Medicine / Issue 9/2016
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI: https://doi.org/10.1007/s11606-016-3751-x

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