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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Digestive Diseases and Sciences
Literature
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Coutts AA, Izzo AA (2004) The gastrointestinal pharmacology of cannabinoids: an update. Curr Opin Pharmacol 4:572–579PubMedCrossRef
2.
Coruzzi G, Adami M, Guaita E, Menozzi A, Bertini S, Giovannini E, Soldani G (2006) Effects of cannabinoid receptor agonists on rat gastric acid secretion: discrepancy between in vitro and in vivo data. Dig Dis Sci 51:310–317PubMedCrossRef
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Horie S, Maruyama T, Yano S, Watanabe K (1996) Neurogenic stimulation of gastric acid secretion by the Na+, K(+)-ATPase inhibitor ouabain in mouse isolated stomach. Gen Pharmacol 27:905–909PubMed
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Izzo AA, Mascolo N, Capasso F (2001) The gastrointestinal pharmacology of cannabinoids. Curr Opin Pharmacol 1:597–603PubMedCrossRef
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Halford JC (2006) Obesity drugs in clinical development. Curr Opin Investig Drugs 7:312–318PubMed
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Metadata
Title
Cannabinoid CB1 Receptor and Gastric Acid Secretion
Author
Francesca Borrelli
Publication date
01-11-2007
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 11/2007
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-006-9507-4

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At a glance: The STEP trials

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

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