Issue 3/2019
Content (16 Articles)
Immunotherapy with checkpoint inhibitors in non-small cell lung cancer: insights from long-term survivors
Ernest Nadal, Bartomeu Massuti, Manuel Dómine, Rosario García-Campelo, Manuel Cobo, Enriqueta Felip
The correlation and prognostic value of serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death-ligand 1 (sPD-L1) in patients with hepatocellular carcinoma
Boyang Chang, Tao Huang, Huajun Wei, Lujun Shen, Duo Zhu, Wenjun He, Qifeng Chen, Huihua Zhang, Yunjian Li, Ruopan Huang, Wang Li, Peihong Wu
CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions
Wanghong Hu, Zhenguo Zi, Yanling Jin, Gaoxin Li, Kang Shao, Qiliang Cai, Xiaojing Ma, Fang Wei
Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model
Diana Llopiz, Marta Ruiz, Lorea Villanueva, Tamara Iglesias, Leyre Silva, Josune Egea, Juan J. Lasarte, Perrine Pivette, Véronique Trochon-Joseph, Bérangère Vasseur, Graham Dixon, Bruno Sangro, Pablo Sarobe
Ex vivo conditioning with IL-12 protects tumor-infiltrating CD8+ T cells from negative regulation by local IFN-γ
Lin Lin, Patricia Rayman, Paul G. Pavicic Jr., Charles Tannenbaum, Thomas Hamilton, Alberto Montero, Jennifer Ko, Brian Gastman, James Finke, Marc Ernstoff, C. Marcela Diaz-Montero
Identification and characterization of an alternative cancer-derived PD-L1 splice variant
Nadia B. Hassounah, Venkat S. Malladi, Yi Huang, Samuel S. Freeman, Ellen M. Beauchamp, Shohei Koyama, Nicholas Souders, Sunil Martin, Glenn Dranoff, Kwok-Kin Wong, Chandra S. Pedamallu, Peter S. Hammerman, Esra A. Akbay
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
Kathleen M. Mahoney, Sachet A. Shukla, Nikolaos Patsoukis, Apoorvi Chaudhri, Edward P. Browne, Arnon Arazi, Thomas M. Eisenhaure, William F. Pendergraft III, Ping Hua, Hung C. Pham, Xia Bu, Baogong Zhu, Nir Hacohen, Edward F. Fritsch, Vassiliki A. Boussiotis, Catherine J. Wu, Gordon J. Freeman
Immune cell infiltration as a biomarker for the diagnosis and prognosis of stage I–III colon cancer
Rui Zhou, Jingwen Zhang, Dongqiang Zeng, Huiying Sun, Xiaoxiang Rong, Min Shi, Jianping Bin, Yulin Liao, Wangjun Liao
Distinct immunological properties of the two histological subtypes of adenocarcinoma of the ampulla of Vater
Min Hwan Kim, Mi Jang, Hoguen Kim, Woo Jung Lee, Chang Moo Kang, Hye Jin Choi
The route of administration dictates the immunogenicity of peptide-based cancer vaccines in mice
Hussein Sultan, Takumi Kumai, Toshihiro Nagato, Juan Wu, Andres M. Salazar, Esteban Celis
CD73 expression in normal and pathological human hepatobiliopancreatic tissues
Amedeo Sciarra, Inês Monteiro, Christine Ménétrier-Caux, Christophe Caux, Benoit Gilbert, Nermin Halkic, Stefano La Rosa, Pedro Romero, Christine Sempoux, Laurence de Leval
Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance
Anna Malyshkina, Elisabeth Littwitz-Salomon, Kathrin Sutter, Jean Alexander Ross, Annette Paschen, Sonja Windmann, Simone Schimmer, Ulf Dittmer
STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes
Morten Nørgaard Andersen, Anders Etzerodt, Jonas H. Graversen, Lisa C. Holthof, Søren K. Moestrup, Marianne Hokland, Holger J. Møller
The effect of everolimus and low-dose cyclophosphamide on immune cell subsets in patients with metastatic renal cell carcinoma: results from a phase I clinical trial
Charlotte M. Huijts, Sinéad M. Lougheed, Zuhir Bodalal, Carla M. van Herpen, Paul Hamberg, Metin Tascilar, John B. Haanen, Henk M. Verheul, Tanja D. de Gruijl, Hans J. van der Vliet
Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer
Alberto A. Chiappori, Charles C. Williams, Jhanelle E. Gray, Tawee Tanvetyanon, Eric B. Haura, Ben C. Creelan, Ram Thapa, Dung-Tsa Chen, George R. Simon, Gerold Bepler, Dmitry I. Gabrilovich, Scott J. Antonia
Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues
Amedeo Sciarra, Inês Monteiro, Christine Ménétrier-Caux, Christophe Caux, Benoit Gilbert, Nermin Halkic, Stefano La Rosa, Pedro Romero, Christine Sempoux, Laurence de Leval