Issue 1/2018
Content (15 Articles)
Quantification of altered tissue turnover in a liquid biopsy: a proposed precision medicine tool to assess chronic inflammation and desmoplasia associated with a pro-cancerous niche and response to immuno-therapeutic anti-tumor modalities
Nicholas Willumsen, Louise B. Thomsen, Cecilie L. Bager, Christina Jensen, Morten A. Karsdal
The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer
Mohammad W. Khan, Abdulrahman Saadalla, Ahmed H. Ewida, Khalid Al-Katranji, Ghadier Al-Saoudi, Zachary T. Giaccone, Fotini Gounari, Ming Zhang, David A. Frank, Khashayarsha Khazaie
Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies
Paulina Nowakowska, Annette Romanski, Nicole Miller, Marcus Odendahl, Halvard Bonig, Congcong Zhang, Erhard Seifried, Winfried S. Wels, Torsten Tonn
Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease
Stefan Diem, Omar Hasan Ali, Christoph J. Ackermann, David Bomze, Viktor H. Koelzer, Wolfram Jochum, Daniel E. Speiser, Kirsten D. Mertz, Lukas Flatz
Administration of low-dose combination anti-CTLA4, anti-CD137, and anti-OX40 into murine tumor or proximal to the tumor draining lymph node induces systemic tumor regression
Jonathan P. O. Hebb, Adriane R. Mosley, Felipe Vences-Catalán, Narendiran Rajasekaran, Anna Rosén, Peter Ellmark, Dean W. Felsher
Bile duct obstruction in a patient treated with nivolumab as second-line chemotherapy for advanced non-small-cell lung cancer: a case report
Jumpei Kashima, Yusuke Okuma, Ryoko Shimizuguchi, Kazuro Chiba
Monitoring the response of urothelial precancerous lesions to Bacillus Calmette-Guerin at the proteome level in an in vivo rat model
Kerem Teke, Nil Guzel, Ali Kemal Uslubas, Murat Kasap, Hasan Yilmaz, Gurler Akpinar, Demir Kursat Yildiz, Ozdal Dillioglugil
HLA class I expression predicts prognosis and therapeutic benefits from tyrosine kinase inhibitors in metastatic renal-cell carcinoma patients
Jiajun Wang, Li Liu, Yang Qu, Wei Xi, Yu Xia, Qi Bai, Ying Xiong, Qilai Long, Jiejie Xu, Jianming Guo
Phase I/II trial of dendritic cell-based active cellular immunotherapy with DCVAC/PCa in patients with rising PSA after primary prostatectomy or salvage radiotherapy for the treatment of prostate cancer
Jitka Fucikova, Michal Podrazil, Ladislav Jarolim, Pavla Bilkova, Michal Hensler, Etienne Becht, Zdenka Gasova, Jana Klouckova, Jana Kayserova, Rudolf Horvath, Anna Fialova, Katerina Vavrova, Klara Sochorova, Daniela Rozkova, Radek Spisek, Jirina Bartunkova
Daunorubicin conjugated with alpha-fetoprotein selectively eliminates myeloid-derived suppressor cells (MDSCs) and inhibits experimental tumor growth
Nikolai N. Belyaev, Nurshat Abdolla, Yuliya V. Perfilyeva, Yekaterina O. Ostapchuk, Vladimir K. Krasnoshtanov, Aikyn Kali, Raikhan Tleulieva
Immunological classification of renal cell carcinoma patients based on phenotypic analysis of immune check-point molecules
Atsunari Kawashima, Takayuki Kanazawa, Kumiko Goto, Mitsunobu Matsumoto, Akiko Morimoto-Okazawa, Kota Iwahori, Takeshi Ujike, Akira Nagahara, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura, Hisashi Wada
Ipilimumab and early signs of pulmonary toxicity in patients with metastastic melanoma: a prospective observational study
Daniel Franzen, Karin Schad, Benedikt Kowalski, Christian F. Clarenbach, Roger Stupp, Reinhard Dummer, Malcolm Kohler
Safety of shortened infusion times for combined ipilimumab and nivolumab
Maximilian Gassenmaier, Hans-Peter Lipp, Alexander Scheu, Nikolaus Benjamin Wagner, Lukas Kofler, Alisa Mueller, Dennis Doecker, Thomas Kurt Eigentler, Claus Garbe, Andrea Forschner
Tumor-infiltrating immune cells as potential biomarkers predicting response to treatment and survival in patients with metastatic melanoma receiving ipilimumab therapy
Tímea Balatoni, Anita Mohos, Eszter Papp, Tímea Sebestyén, Gabriella Liszkay, Judit Oláh, Anita Varga, Zsuzsanna Lengyel, Gabriella Emri, István Gaudi, Andrea Ladányi
2nd Symposium on Advances in Cancer Immunology and Immunotherapy, December 15–17, 2016, Athens, Greece
Pinelopi Samara, Athanasios Kotsakis, Ourania Tsitsilonis, Vassilis Georgoulias, Graham Pawelec, Constantin N. Baxevanis