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Cancer Chemotherapy and Pharmacology

Issue 5/2012

Content (16 Articles)

Review Article

Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal?

Hannah R. Wardill, Joanne M. Bowen, Rachel J. Gibson

Original Article

PPAR signaling pathway may be an important predictor of breast cancer response to neoadjuvant chemotherapy

Y. Z. Chen, J. Y. Xue, C. M. Chen, B. L. Yang, Q. H. Xu, F. Wu, F. Liu, X. Ye, X. Meng, G. Y. Liu, Z. Z. Shen, Z. M. Shao, J. Wu

Original Article

Phase II study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small cell lung cancer

Minoru Fukuda, Yoichi Nakamura, Akitoshi Kinoshita, Yoshifumi Soejima, Hiroyuki Yamaguchi, Takaya Ikeda, Koichi Izumikawa, Hiroshi Takatani, Masaaki Fukuda, Hiroshi Soda, Nobuyuki Hayashi, Kazuhiro Tsukamoto, Mikio Oka, Shigeru Kohno

Original Article

Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors

Anne-Charlotte Dubbelman, Alana Upthagrove, Jos H. Beijnen, Serena Marchetti, Eugene Tan, Kimberly Krone, Suraj Anand, Jan H. M. Schellens

Original Article

A phase II study of docetaxel and oxaliplatin combination in recurrent gastric cancer patients after fluoropyrimidine and/or cisplatin adjuvant treatment: a Korean Cancer Study Group Protocol ST06-02

Yoon Hee Choi, Sang Cheul Oh, Jun Suk Kim, Seung-Hyun Nam, Bong-Seog Kim, Sang-Hee Cho, Ik Joo Chung, Eun-Kee Song, Chang-Yeol Yim, Jin Ho Baek, Hei-Cheul Jeung, Young Seon Hong, Sung Hyun Yang, Hye Jin Kang

Original Article

A phase I and pharmacokinetic study of elisidepsin (PM02734) in patients with advanced solid tumors

R. Salazar, R. J. Jones, A. Oaknin, D. Crawford, C. Cuadra, C. Hopkins, M. Gil, C. Coronado, A. Soto-Matos, M. Cullell-Young, J. L. Iglesias Dios, T. R. J. Evans

Original Article

A phase II study of concurrent chemoradiotherapy with weekly docetaxel and cisplatin in advanced oesophageal cancer

Hyun-Jeong Shim, Dae-Eun Kim, Jun-Eul Hwang, Woo-Kyun Bae, Taek-Keun Nam, Kook-Joo Na, Sang-Hee Cho, Ik-Joo Chung

Original Article

Phase I/II study of S-1 combined with biweekly irinotecan chemotherapy in previously treated advanced non-small cell lung cancer

Hiroki Goya, Hiroshi Kuraishi, Shigeru Koyama, Takashi Ichiyama, Fumiaki Yoshiike, Kazuya Hirai, Toshihiko Agatsuma, Kazunari Tateishi, Shintaro Kanda, Hiroshi Yamamoto, Keishi Kubo, Tomonobu Koizumi

Original Article

Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors

Jeffrey R. Infante, Vicki L. Keedy, Suzanne F. Jones, William C. Zamboni, Emily Chan, Johanna C. Bendell, Wooin Lee, Huali Wu, Satoshi Ikeda, Hiroshi Kodaira, Mace L. Rothenberg, Howard A. Burris III

Original Article

Everolimus synergizes with gefitinib in non-small-cell lung cancer cell lines resistant to epidermal growth factor receptor tyrosine kinase inhibitors

Song Dong, Xu-Chao Zhang, Hua Cheng, Jian-Quan Zhu, Zhi-Hong Chen, Yi-Fang Zhang, Zhi Xie, Yi-Long Wu

Open Access Original Article

Population pharmacokinetics of farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer

Colm Farrell, Charles Schweizer, Jason Wustner, Susan Weil, Masayuki Namiki, Tomohisa Nakano, Kenya Nakai, Martin D. Phillips

Original Article

Phosphorylated AMP-activated protein kinase expression associated with prognosis for patients with gastric cancer treated with cisplatin-based adjuvant chemotherapy

Byung Woog Kang, Ji Yun Jeong, Yee Soo Chae, Soo Jung Lee, Yoo Jin Lee, Jun Young Choi, In-Kyu Lee, Seong Woo Jeon, Han Ik Bae, Da Keun Lee, Oh-kyoung Kwon, Ho Young Chung, Wansik Yu, Jong Gwang Kim

Original Article

A biomarker profile for predicting efficacy of cisplatin–vinorelbine therapy in malignant pleural mesothelioma

Zarah Glad Zimling, Jens Benn Sørensen, Thomas Alexander Gerds, Cecilia Bech, Claus Bøgelund Andersen, Eric Santoni-Rugiu

Clinical Trial Report

Phase I trial of pomalidomide given for patients with advanced solid tumors

Matthew M. Cooney, Charles Nock, Joseph Bokar, Smitha Krishnamurthi, Joseph Gibbons, Mary Beth Rodal, Anne Ness, Scot C. Remick, Robert Dreicer, Afshin Dowlati

Erratum

Erratum to: The “survivin suppressants” NSC 80467 and YM155 induce a DNA damage response

Trevor G. Glaros, Luke H. Stockwin, Michael E. Mullendore, Brian Smith, Bethanie L. Morrison, Dianne L. Newton

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine